全文获取类型
收费全文 | 2158篇 |
免费 | 117篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 315篇 |
妇产科学 | 33篇 |
基础医学 | 255篇 |
口腔科学 | 56篇 |
临床医学 | 152篇 |
内科学 | 327篇 |
皮肤病学 | 44篇 |
神经病学 | 166篇 |
特种医学 | 88篇 |
外科学 | 195篇 |
综合类 | 14篇 |
预防医学 | 181篇 |
眼科学 | 188篇 |
药学 | 131篇 |
中国医学 | 1篇 |
肿瘤学 | 129篇 |
出版年
2023年 | 11篇 |
2022年 | 19篇 |
2021年 | 31篇 |
2020年 | 24篇 |
2019年 | 32篇 |
2018年 | 48篇 |
2017年 | 25篇 |
2016年 | 39篇 |
2015年 | 45篇 |
2014年 | 56篇 |
2013年 | 87篇 |
2012年 | 127篇 |
2011年 | 162篇 |
2010年 | 68篇 |
2009年 | 77篇 |
2008年 | 121篇 |
2007年 | 133篇 |
2006年 | 153篇 |
2005年 | 147篇 |
2004年 | 123篇 |
2003年 | 121篇 |
2002年 | 110篇 |
2001年 | 62篇 |
2000年 | 45篇 |
1999年 | 43篇 |
1998年 | 29篇 |
1997年 | 24篇 |
1996年 | 13篇 |
1995年 | 15篇 |
1994年 | 12篇 |
1993年 | 12篇 |
1992年 | 24篇 |
1991年 | 19篇 |
1990年 | 16篇 |
1989年 | 22篇 |
1988年 | 13篇 |
1987年 | 17篇 |
1986年 | 10篇 |
1985年 | 10篇 |
1984年 | 7篇 |
1983年 | 11篇 |
1982年 | 12篇 |
1981年 | 4篇 |
1979年 | 8篇 |
1974年 | 4篇 |
1970年 | 4篇 |
1955年 | 7篇 |
1949年 | 4篇 |
1925年 | 3篇 |
1904年 | 3篇 |
排序方式: 共有2285条查询结果,搜索用时 31 毫秒
81.
Claiton Heitz Roger Correa de Barros Berthold Heloísa Har Machado Lucas Sant’Ana Rogério Belle de Oliveira 《Oral and maxillofacial surgery》2014,18(1):81-86
Purpose
Myofibroma is a rare benign spindle cell neoplasm, and the aim of the present study was to carry out a literature review and present a clinical case of a patient with a myofibroma in the submandibular region and its management.Conclusions
Diagnosis of myofibroma can be reached by a histopathologic and immunohistochemical analysis and surgical excision is the treatment of choice. 相似文献82.
Bührer Christoph Ensenauer Regina Jochum Frank Kalhoff Hermann Körner Antje Koletzko Berthold Lawrenz Burkhard Mihatsch Walter Rudloff Silvia Zimmer Klaus-Peter 《Monatsschrift für Kinderheilkunde》2020,168(9):834-841
Monatsschrift Kinderheilkunde - Eine adäquate Energie- und Nährstoffversorgung ist Grundlage für ein gesundes Wachstum und Voraussetzung für die Erhaltung von Gesundheit und... 相似文献
83.
高血压是全球主要的公共健康问题,包括高血压在内的心血管疾病已成为我国首要的死亡原因,高血压和高血压前期是主要的危险因素,它们显著增加了心血管疾病的病死率[1-2]。体重指数(body mass index,BMI)的升高增加了高血压、脑中风和心肌梗死等心血管疾病发病的风险,BMI与血压升高所致的心血管疾病发病风险不尽相 相似文献
84.
Peak weight velocity in infancy is negatively associated with lung function in adolescence
下载免费PDF全文
![点击此处可从《Pediatric pulmonology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
85.
Garnier Y Kadyrov M Gantert M Einig A Rath W Huppertz B 《European journal of obstetrics, gynecology, and reproductive biology》2008,140(2):152-157
OBJECTIVES: Antenatal infections are associated with an increased risk of perinatal morbidity and mortality. Systemic application of endotoxins to the fetus results in an increase in placental vascular resistance and chronic reduction in umbilical blood flow. We studied morphological alterations of the placenta in response to fetal inflammation in the preterm sheep. STUDY DESIGN: Therefore, 14 fetal sheep were chronically instrumented at a mean gestational age of 107+/-1 days (term is 147 days). Four days after surgery fetuses received 100 ng lipopolysaccharide (LPS; n=8) or saline (control; n=6) intravenously. Fetal heart rate and arterial blood pressure were monitored continuously while blood gases and acid-base balance were measured at time points 0, +1, +3, +6, +12, +24, +48 and +72 h. Three days after LPS application placental cotyledons were analyzed by immunohistochemistry and morphometry. Different primary antibodies like AE 1 and AE 3 against cytokeratins were used. Secondary antibodies were visualized with 3-amino-9-ethylcarbazole (AEC) or using the Vectastain kit (Vector Laboratories, Burlingame, CA). Double staining was carried out first by utilizing Vectastain kit (black), followed by AEC staining (red). Counterstaining was performed with haematoxylin. RESULTS: Fetal tachycardia and hypertension were induced transiently during the first 12h after LPS application. Fetuses suffered from mild hypoxaemia while acidemia was absent. Morphometry revealed a non-significant shift in the relation of maternal and fetal placental compartments towards the maternal parts in response to LPS treatment. Endotoxin induced an increased proliferation in both compartments of the placenta with a 3.2-fold increase on the maternal and a 1.8-fold increase on the fetal side. CONCLUSIONS: Systemic endotoxin exposure of the preterm fetal sheep leads to a change in the gross organization of the placenta and changes in the proliferation patterns in both placental compartments. These rearrangements inside the placenta may disturb its organ function and subsequently lead to fetal morbidity associated with the fetal inflammatory response syndrome and chronic placental dysfunction, respectively. 相似文献
86.
Dr. Berthold Benecke 《Virchows Archiv : an international journal of pathology》1872,55(3-4):496-511
Ohne Zusammenfassung 相似文献
87.
Bartsch DK Sina-Frey M Lang S Wild A Gerdes B Barth P Kress R Grützmann R Colombo-Benkmann M Ziegler A Hahn SA Rothmund M Rieder H 《Annals of surgery》2002,236(6):730-737
OBJECTIVE: To evaluate the prevalence of mutations in the CDKN2A gene encoding p16 and p14 in familial pancreatic cancer (FPC). SUMMARY BACKGROUND DATA: The genetic basis of FPC is still widely unknown. Recently, it has been shown that germline mutations in the p16 tumor suppressor gene can predispose to pancreatic cancer. The presence of p14 germline mutations has yet not been determined in this setting. METHODS: Eighteen families with at least two first-degree relatives with histologically confirmed pancreatic cancer and five families with at least one patient with pancreatic cancer and another first-degree relative with malignant melanoma of the German National Case Collection for Familial Pancreatic Cancer were analyzed for CDKN2A germline mutations including p16 and p14 by direct DNA sequencing. All participating family members were genetically counseled and evaluated by a three-generation pedigree. RESULTS: None of 18 FPC families without malignant melanoma revealed p16 mutations, compared to 2 of 5 families with pancreatic cancer and melanoma. Truncating p16 germline mutations Q50X and E119X were identified in the affected patients of pancreatic cancer plus melanoma families. None of the 23 families revealed p14 germline mutations. CONCLUSIONS: CDKN2A germline mutations are rare in FPC families. However, these data provide further evidence for a pancreatic cancer-melanoma syndrome associated with CDKN2A germline mutations affecting p16. Thus, all members of families with combined occurrence of pancreatic cancer and melanoma should be counseled and offered screening for p16 mutations to identify high-risk family members who should be enrolled in a clinical screening program. 相似文献
88.
89.
90.
Torstein Vik Veit Grote Joauqín Escribano Jerzy Socha Elvira Verduci Michaela Fritsch Clotilde Carlier Rüdiger von Kries Berthold Koletzko for the European Childhood Obesity Trial Study Group 《Acta paediatrica (Oslo, Norway : 1992)》2009,98(8):1344-1348
Aim: To study if infant crying is associated with maternal postnatal depression.
Methods: Data from 1015 mothers and their children participating in a prospective European multicentre study were analysed. Infantile colic and prolonged crying were defined as excessive crying as reported by the mothers 2 and 6 months after delivery, and at the same time the mothers completed the Edinburgh Postnatal Depression Scale (EPDS).
Results: In cross-sectional analyses, infant crying was associated with high EPDS scores both 2 (OR: 4.4; 95% CI: 2.4–8.2) and 6 months postpartum (OR: 10.8; 95% CI: 4.3–26.9). More than one-third of the others of infants with prolonged crying had high EPDS scores 6 months postpartum. Longitudinal analyses showed that mothers of infants with colic had increased odds of having high EPDS scores 6 months after delivery even if crying had resolved (OR: 3.7; 95% CI: 1.4–10.1).
Conclusion: Both infantile colic and prolonged crying were associated with high maternal depression scores. Most noteworthy, infantile colic at 2 months of age was associated with high maternal depression scores
4 months later. 相似文献
Methods: Data from 1015 mothers and their children participating in a prospective European multicentre study were analysed. Infantile colic and prolonged crying were defined as excessive crying as reported by the mothers 2 and 6 months after delivery, and at the same time the mothers completed the Edinburgh Postnatal Depression Scale (EPDS).
Results: In cross-sectional analyses, infant crying was associated with high EPDS scores both 2 (OR: 4.4; 95% CI: 2.4–8.2) and 6 months postpartum (OR: 10.8; 95% CI: 4.3–26.9). More than one-third of the others of infants with prolonged crying had high EPDS scores 6 months postpartum. Longitudinal analyses showed that mothers of infants with colic had increased odds of having high EPDS scores 6 months after delivery even if crying had resolved (OR: 3.7; 95% CI: 1.4–10.1).
Conclusion: Both infantile colic and prolonged crying were associated with high maternal depression scores. Most noteworthy, infantile colic at 2 months of age was associated with high maternal depression scores
4 months later. 相似文献