全文获取类型
收费全文 | 3780篇 |
免费 | 323篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 314篇 |
妇产科学 | 45篇 |
基础医学 | 148篇 |
口腔科学 | 203篇 |
临床医学 | 597篇 |
内科学 | 927篇 |
皮肤病学 | 91篇 |
神经病学 | 155篇 |
特种医学 | 118篇 |
外科学 | 494篇 |
综合类 | 170篇 |
一般理论 | 4篇 |
预防医学 | 486篇 |
眼科学 | 38篇 |
药学 | 102篇 |
2篇 | |
中国医学 | 75篇 |
肿瘤学 | 140篇 |
出版年
2024年 | 8篇 |
2023年 | 57篇 |
2022年 | 131篇 |
2021年 | 159篇 |
2020年 | 169篇 |
2019年 | 97篇 |
2018年 | 73篇 |
2017年 | 40篇 |
2016年 | 50篇 |
2015年 | 44篇 |
2014年 | 36篇 |
2013年 | 51篇 |
2012年 | 222篇 |
2011年 | 306篇 |
2010年 | 140篇 |
2009年 | 77篇 |
2008年 | 245篇 |
2007年 | 303篇 |
2006年 | 296篇 |
2005年 | 282篇 |
2004年 | 291篇 |
2003年 | 324篇 |
2002年 | 203篇 |
2001年 | 204篇 |
2000年 | 83篇 |
1999年 | 28篇 |
1998年 | 22篇 |
1997年 | 14篇 |
1996年 | 8篇 |
1995年 | 5篇 |
1993年 | 3篇 |
1991年 | 18篇 |
1990年 | 13篇 |
1989年 | 12篇 |
1988年 | 9篇 |
1987年 | 8篇 |
1986年 | 7篇 |
1985年 | 4篇 |
1984年 | 6篇 |
1983年 | 8篇 |
1982年 | 13篇 |
1980年 | 4篇 |
1979年 | 6篇 |
1978年 | 4篇 |
1977年 | 5篇 |
1975年 | 10篇 |
1974年 | 5篇 |
1973年 | 4篇 |
1965年 | 2篇 |
1958年 | 2篇 |
排序方式: 共有4125条查询结果,搜索用时 62 毫秒
61.
目的探讨肿瘤细胞减灭术(CRS)及腹腔热灌注化疗(HIPEC)联合肝切除治疗结直肠癌腹膜转移(CRPM)合并肝转移(LM)的安全性及有效性。
方法回顾性收集中国医学科学院肿瘤医院结直肠外科自2017年6月至2019年6月采用CRS+HIPEC联合肝切除治疗的16例CRPM合并孤立LM患者的临床病理资料。
结果男性6例,女性10例,中位年龄62岁。全组患者接受CRS+HIPEC联合同步肝切除,肝脏转移瘤均获得完整切除。中位总生存期25个月,中位无病生存期9个月。1年及3年总生存率分别为75.0%及37.0%,1年及3年无病生存率分别为50.0%及9.4%。6例(37.5%)出现轻度并发症(Clavien-Dindo Ⅰ~Ⅱ),4例(25.0%)出现严重并发症(Ⅲ~Ⅳ)。
结论CRPM合并孤立的、能完整切除的LM的患者接受CRS+HIPEC联合同期肝切除是安全可行的,同时可为患者带来一定生存获益。 相似文献
62.
Rodgers H Dennis M Cohen D Rudd A;British Association of Stroke Physicians 《Age and ageing》2003,32(2):211-217
BACKGROUND: the National Service Framework for Older People requires every general hospital which cares for stroke patients to introduce a specialist stroke service by 2004. OBJECTIVE: to describe the organisation and staffing of specialist hospital-based stroke services in the UK. DESIGN: a national postal survey of consultant members of the British Association of Stroke Physicians (BASP) seeking details of the provision of neurovascular clinics, acute stroke units (ASUs), stroke rehabilitation units (SRUs), and the organisation and staffing of these services. RESULTS: the response rate was 91/126 (72%). Fifty-four neurovascular clinics, 40 ASUs and 68 SRUs were identified. Neurovascular clinics used a number of strategies to maintain rapid access and 30 (56%) were run by a single consultant. Only 50% ASUs usually admitted patients within 24 h of stroke. As the number of beds available on ASUs and SRUs did not reflect the total number of stroke in-patients, 21 (53%) ASUs and 45 (79%) SRUs had admission criteria. Training opportunities were limited: 37% ASUs and 82% SRUs had no specialist registrar. The therapy sessions (1 session=half a day) available per bed per week on a SRU were: physiotherapy 0.8; occupational therapy 0.6; speech and language therapy 0.25. CONCLUSIONS: significant development is needed to achieve the NSF target for hospital-based stroke services as few Trusts currently have all components in place and even when available not all stroke patients have access to specialist care. Stroke specialists will be required to run these services but training opportunities are currently limited. Stroke unit therapy staffing levels were lower than was available in randomised controlled trials. 相似文献
63.
64.
为实现终止结核病流行策略目标,迫切需要实施更强有力的措施来改善结核病患者的发现和治疗管理,而主动筛查作为实现目标的重要组成部分,旨在确保结核病患者的早期诊断。中国防痨协会结核病控制专业分会和老年结核病防治专业分会与《中国防痨杂志》编辑委员会共同组织专家,在解读吸收世界卫生组织2021年最新指南证据和建议的基础上,补充了后续新发表的文献和我国国内的相关文献和研究证据,结合中国结核病防治实践和研究结果制订了本指南。本指南系统总结了症状筛查、胸部影像学检查、C反应蛋白检测等筛查技术的特点,提出了在肺结核患者密切接触者、既往结核病患者、HIV/AIDS者、老年人、糖尿病患者和高疫情地区的一般人群等社区人群中开展肺结核主动筛查的方式,为国家和各地完善和优化重点人群肺结核主动筛查策略提供循证依据。 相似文献
65.
中华医学会肝病学分会 《临床肝胆病杂志》2022,38(1):50-61
2015年我国第一个原发性硬化性胆管炎(PSC)的专家共识颁布。近年来PSC的临床研究提供了PSC新的研究数据和资料。为此,中华医学会肝病学分会自身免疫性肝病学组组织专家组对近年来的文献证据进行了评估,制定了本指南。本指南共有PSC推荐意见21条。为了利于鉴别PSC和IgG4相关硬化性胆管炎(IgG4-SC),也附有IgG4-SC的10条推荐意见。本指南的目的是为临床PSC和IgG4-SC的诊治提供参考和指导。 相似文献
66.
Pietro Palmisano MD Matteo Ziacchi MD Ernesto Ammendola MD Antonio D'Onofrio MD Gabriele Dell'Era MD Mattia Laffi MD Mauro Biffi MD Gerardo Nigro MD PhD Walter Bianchi MD Eleonora Prenna MD Andrea Angeletti MD Alessandro Guido MD Giulia Stronati MD Germano Gaggioli MD Antonio Dello Russo MD Michele Accogli MD Federico Guerra MD Italian Association of Arrhythmology Cardiac Pacing 《Journal of cardiovascular electrophysiology》2021,32(6):1712-1723
67.
Broers B Helbling B François A Schmid P Chuard C Hadengue A Negro F;Swiss Association for the Study of the Liver 《Journal of hepatology》2005,42(3):323-328
BACKGROUND/AIMS: Treatment with interferon-alpha (IFN-alpha) may eradicate HCV in most acute hepatitis C patients, thus preventing chronic hepatitis and avoiding less efficacious combination therapy. METHODS: In a prospective study, we evaluated the impact of barriers to successful start and completion of treatment of acute and subacute (<12 months from infection) hepatitis C with pegylated IFN-alpha2b, 1.5 microg/kg, QW, for 24 weeks. RESULTS: Out of 27 patients (22 were active intravenous drug users [IVDU]), 5 cleared HCV spontaneously. Antiviral treatment was indicated in 22 patients: six refused therapy for fear of side effects, whereas two others were lost to observation. Eight patients completed the treatment or received >80% of the scheduled drug: seven (88%) were sustained virological responders 24 weeks after the end of treatment. Six patients (all IVDU) stopped prematurely due to side effects: only one had a sustained virological response. Based on an intent-to-treat analysis, and considering all 14 patients in whom at least one dose of drug was administered, only 8 (57%) became sustained virological responders. CONCLUSIONS: Treatment of acute hepatitis C with pegylated IFN-alpha is highly beneficial, but its effectiveness is affected by a poor rate of acceptance and/or adherence to currently available regimens, especially in IVDU and women. 相似文献
68.
【摘要】 为促进布-加综合征(BCS)介入治疗围手术期护理标准化和规范化,保障患者安全,促进患者康复,特制定本共识。本共识以我国BCS的介入治疗临床实践为基础,结合国内外相关文献,就BCS介入治疗的专科护理评估、术中护理配合、疗效评价、术后护理、常见严重并发症及其护理进行了全面阐述,旨在为BCS介入治疗围手术期护理提供指导与参考。 相似文献
69.
中华医学会儿科学分会消化学组 《中国当代儿科杂志》2022,24(10):1069-1077
小肠疾病是消化系统疾病诊治难点之一,检查技术有限,严重制约了儿童消化道疾病的诊疗水平。随着小肠镜在儿科临床应用的推广与小肠镜设备和附件的优化,小肠镜技术为儿科消化道诊疗提供了新的手段,但临床操作规范化和镜下治疗面临诸多问题和挑战。为规范儿童小肠镜诊疗技术及提高小肠疾病的诊疗水平,中华医学会儿科学分会消化学组牵头,组织专家充分讨论,并参考儿童小肠镜临床应用的最新进展,制定了儿童小肠镜临床应用管理专家共识。 相似文献
70.
Retrospective investigation of hospitalised patients with atrial fibrillation in mainland China 总被引:2,自引:0,他引:2
Wen-Hang QI;Society of Cardiology Chinese Medical Association 《International journal of cardiology》2005,105(3):283-287
OBJECTIVE: To evaluate the epidemiology and status of atrial fibrillation in China. METHODS: Retrospective analysis of hospital records of patients with a primary diagnosis of atrial fibrillation, discharged between January 1999 and December 2001. RESULTS: Data were analysed from 9297 patients (mean age 65.5 years) from 41 hospitals in mainland China. During the period studied, atrial fibrillation admissions (mean 7.9%) increased as a proportion of cardiovascular admissions. The distribution of atrial fibrillation increased with age. Causes and associated conditions were advanced age (58.1%), hypertension (40.3%), coronary heart disease (34.8%), heart failure (33.1%), rheumatic valvular disease (23.9%), idiopathic atrial fibrillation (7.4%), cardiomyopathy (5.4%) and diabetes (4.1%). Permanent atrial fibrillation accounted for almost half of the patients (49.5%), and paroxysmal and persistent atrial fibrillation the remainder (33.7% and 16.7%, respectively). Paroxysmal atrial fibrillation was treated mainly by rhythm control (56.4%). In 82.8% of patients with chronic atrial fibrillation, a rate-control strategy was used. The prevalence of stroke was 17.5%. In non-valvular atrial fibrillation, risk factors associated with stroke included advanced age, history of hypertension, coronary heart disease and type of atrial fibrillation. A total of 64.5% of patients received antithrombotic therapy, predominantly with antiplatelet agents. Patients managed with antiplatelet or anticoagulant drugs had a significantly lower stroke rate than those receiving neither treatment, but there was no significant difference between antiplatelet and anticoagulant agents. CONCLUSION: Most of the atrial fibrillation-related epidemiological factors in this population were similar to those reported in other countries. Antiplatelet and anticoagulant treatment both reduced stroke rate significantly. 相似文献