Statistical modelling of human blood carbon dioxide partial pressure

This paper deals with statistical modelling of blood carbon dioxide partial pressure pCO 2. The clinical measurements were carried out in the Arab Centre for Heart and Special Surgery in Amman. The statistical analysis of the results obtained demonstrates that pCO 2 for arterial, venous and capillary blood have histograms approaching normal ones. Moreover, the experimental data suggest that the blood pCO 2 can be expressed by a linear regression model. Making use of this regression model, the blood pCO 2 population can indirectly be obtained with accuracy fulfilling clinical requirements. Therefore, this approach will not only lead to less invasive methods but will also result in decreasing the cost of projected analyser for blood gas analysis. The implementation of this proposed regression equation ensures the effectiveness of the model as an indirect method for pCO 2 measurements.     

Syncopal migraine

Objective  

A subgroup of syncope patients report migraine headaches immediately preceding or following syncope, and some respond to anti-migrainous prophylactic agents. This study aimed to describe the frequency of migrainous features concurrent with episodes of syncope and to propose clinical criteria for assessing whether a migrainous mechanism might underlie syncope.     

Tissue Doppler assessment of left ventricular diastolic function in rheumatic mitral stenosis

BackgroundLeft ventricular systolic and diastolic functions are reported to be altered in mitral stenosis. Although conventional Doppler ultrasound recording of transmitral flow is used in the assessment of left ventricular diastolic function, yet, in patients with mitral stenosis, it is altered by mitral stenosis itself and thus precludes the proper assessment of LV diastolic function.Aim of the workThe aim of this work is to assess LV diastolic function using pulsed tissue Doppler interrogation of mitral annulus motion in patients with rheumatic mitral stenosis.Patients and methodsTwelve patients with established diagnosis of rheumatic mitral stenosis in normal sinus rhythm were obtained from outpatient clinic of Cardiology Department in Mansura specialized hospital. Thirteen age and sex matched controls with completely normal echo-Doppler study were taken for comparison. All patients were subjected to thorough history taking including dyspnea grading according to NYHA score, clinical examination, 12 lead surface electrocardiogram and most importantly echo-Doppler study.ResultsWe found statistically significant higher peak mitral annular E_a velocity from septal, anterior, inferior and lateral portions of the mitral annulus in controls compared with mitral stenosis patients as well as their averaged values. There is no statistically significant difference regarding peak mitral annular A_a velocity from septal, anterior, inferior and lateral portions of the mitral annulus between both groups as well as their averaged values. The ratio of early to late mitral annular velocities from all recorded sites was statistically significantly higher in the controls compared with mitral stenosis patients.ConclusionsTDI of mitral annulus may provide potential diagnostic role for assessment of LV diastolic function in patients with mitral stenosis.