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61.
62.
Tok A Ozturk S Tepeler A Tefekli AH Kazancioglu R Muslumanoglu AY 《International urology and nephrology》2009,41(1):219-223
Since percutaneous nephrolithotomy (PNL) is a surgical intervention, it may show deteriorative effects on renal function in
the early postoperative period. In this study, the deteriorative effects of PNL on renal function were investigated in the
geriatric population, and it was compared to the non-geriatric population.
A total of 711 patients [64 in the geriatric group (female/male ratio: 33/31, mean age: 70.4 ± 4.2 years), 647 in the non-geriatric
group (female/male ratio: 267/380, mean age: 40.9 ± 12.7 years)] were included in the study. Demographic data, biochemical
parameters, stone diameters, duration of the operation and estimated glomerular filtration rates (eGFR) were recorded both
preoperatively and postoperatively.
The eGFR ratio (post-/preoperative) was 1.13 ± 1.00 in the geriatric group, 0.98 ± 0.20 in the non-geriatric group (P < 0.001). Although the mean stone diameter was larger in the geriatric group than the non-geriatric group (10.08 ± 6.5 mm,
8.28 ± 5.54 mm, P = 0.037), the mean duration of the operation was shorter in the geriatric group than in the non-geriatric group (55.7 ± 13.6 min,
61.3 ± 20.9 min, P = 0.036). Hematocrit, hemoglobin, urea levels, and grade of hydronephrosis were not different between the groups.
Renal function impairment is expected to be common in the geriatric patient population since they already have lower basal
renal function. In the present study, the ratio of postoperative to preoperative eGFR was higher in the geriatric group. Hematocrit,
hemoglobin, and urea levels and degree of hydronephrosis of these two groups did not show a great difference. The relatively
short duration of the operation in the geriatric group and the diversity of perioperative and postoperative care of these
two groups may explain the difference. 相似文献
63.
Kahyaoğlu O Cavuşoğlu H Müslüman AM Kaya RA Yilmaz A Sahin Y Dadaş B Aydin Y 《Turkish neurosurgery》2007,17(4):264-268
Transsphenoidal encephaloceles are rare and the transsellar variety is the least common. We present a 1-year-old male patient with transsellar transsphenoidal encephalocele which herniated into the oral cavity through the congenital split palate. The patient was operated on using a combined transcranial and transpalatal approach without mortality or permanent morbidity. Clinical findings, imaging reviews, surgical repair techniques and postoperative morbidity are discussed with the relevant literature. We conclude that repair of a transsphenoidal encephalocele should be coordinated between a team of neurosurgeons and otorhinolaryngologists. Our surgical outcome supports a transcranial approach for the treatment of these difficult lesions, with transpalatal dissection and exposure. 相似文献
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Background
Nocturnal enuresis is an important problem among young children living in Turkey. The purpose of this study was to determine the possible differences in the prevalence of enuresis between children in boarding school and daytime school and the association of enuresis with sociodemographic factors. 相似文献67.
68.
Fernandez-Cabezudo MJ Ali SA Ullah A Hasan MY Kosanovic M Fahim MA Adem A al-Ramadi BK 《Toxicology and applied pharmacology》2007,218(3):215-226
Persistent exposure to inorganic lead (Pb) is known to adversely affect the immune system. In the present study, we assessed the effect of chronic Pb exposure on susceptibility to infection by the facultative intracellular pathogen Salmonella enterica serovar Typhimurium. Mice were exposed to 10 mM Pb-acetate in drinking water for approximately 16 weeks, resulting in a significant level of Pb in the blood (106.2+/-8.9 microg/dl). Pb exposure rendered mice susceptible to Salmonella infection, manifested by increased bacterial burden in target organs and heightened mortality. Flow cytometric analysis of the splenic cellular composition in normal and Pb-exposed mice revealed no gross alteration in the ratios of B and T lymphocytes or myeloid cells. Similarly, the capacity of B and T cells to upregulate the expression of activation antigens in response to mitogenic or inflammatory stimuli was not hindered by Pb exposure. Analysis of the ability of ex vivo-cultured splenocytes to secrete cytokines demonstrated a marked reduction in IFN-gamma and IL-12p40 production associated with Pb exposure. In contrast, secretion of IL-4 by splenocytes of Pb-treated mice was 3- to 3.6-fold higher than in normal mice. The increased capacity to produce IL-4 correlated with a shift in the in vivo anti-Salmonella antibody response from the protective IgG2a isotype to the Th2-induced IgG1 isotype. We conclude that chronic exposure to high levels of Pb results in a state of immunodeficiency which is not due to an overt cytotoxic or immunosuppressive mechanism, but rather is largely caused by a shift in immune responsiveness to Th2-type reactions. 相似文献
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Esteller Moré E Pons Calabuig N Romero Vilariño E Puigdollers Pérez A Segarra Isern F Matiñó Soler E Ademà Alcover JM 《Acta otorrinolaringologica espanola》2011,62(2):132-139
IntroductionThe recent interest in sleep-related breathing disorders has re-opened the old debate as to whether there is a causal relationship between upper respiratory obstruction and abnormalities in dentofacial development.ObjectiveTo establish the impact of dentofacial development on sleep-related breathing disorders in children.MethodThis is a prospective study in which the dentofacial studies of 30 children, diagnosed with a sleep-related breathing disorder using polysomnography, were compared with a control group of 30 healthy children. The ages of both groups were between 3 and 13 years.ResultsThe statistical analysis showed significant differences between the groups in the proportion of children with a narrow palate (83% of the problem group and 57% in the control; P = 0.024) and cross bite (40% and 13%; P = 0.020). On comparing the angles measured, the only statistically-significant difference was the skull base-mandibular plane angle: The problem children group had a mean of 37.59 ± 5.56 and the control group, a mean of 34.41 ± 4.62 (P = 0.023).ConclusionChildren with sleep-related breathing disorders have abnormalities in facial and dental development caused by upper respiratory obstruction. These anomalies, vertical growth of the face, narrow palate and dental occlusion changes should be taken into account when assessing the indication for a adenotonsillectomy. 相似文献