复方甘草酸苷治疗斑秃的疗效观察

我们于2005年10月~2006年12月,采用口服复方甘草酸苷(美能片)联合恩肤霜外用治疗斑秃50例取得满意疗效,现报道如下。1材料和方法1.1试剂和材料恩肤霜:规格10g,芜湖三益制药有限公司生产;美能片:规格25mg/片,日本米诺发源制药株式会社生产。1.2研究对象2005年10月~2006年12月我院门诊102例斑秃患者,符合斑秃诊断标准1。其中男54例,女48例,年龄中位数17岁。随机分为两组,实验组50例,对照组52例,两组年龄中位数经t检验,P>0.05。两组的性别,斑秃的病程分期,病情轻、中、重度分别经χ2检验,P>0.05。说明两组有可比性。1.3给药方法实验组:美能片7…     

经皮冠状动脉腔内成形术后夹层与早期狭窄加重的关系

OBJECTIVE: To investigate the early natural course of dissection after PTCA and its relation to early luminal deterioration. METHODS: One hundred and five patients who underwent relook coronary arteriography within 24 hours of PTCA were retrospectively analyzed. The patients were subdivided into no dissection and type A, B, C, D, and E dissection. Minimal luminal diameter (MLD) was measured immediately after PTCA and at relook coronary arteriography. The changes were correlated with the severity of the dissections. RESULTS: Immediately after PTCA, the MLD in all 6 groups was > 2.0 mm. Except for type A dissection, the MLD, however, was deteriorated significantly at the relook coronary arteriography next day. The factors contributing to the deterioration were analyzed by covariance analysis, which showed a significant linear relation with the MLD immediately after PTCA and the type of dissection. Multivariate stepwise regression analysis was used to investigate if the patients' demographic factors and coronary lesion characteristics were also related to the MLD deterioration. The results showed that multivessel disease and the type of dissection were two independent risk factors of the MLD deterioration. CONCLUSION: Even if the results immediately after PTCA were acceptable, MLD will deteriorate over time. The degree of the deterioration was not only related to elastic recoil, but also to the type of dissection. Type C, D and E dissections were unstable, causing much more damage to the MLD than type A and B dissections, which mandated immediate stent implantation to prevent early luminal deterioration and late restenosis. Stent implantation was usually unnecessary in type A and B dissections. Multivessel disease was also involved in the process of the MLD deterioration. The mechanism is unclear, but might be related to coronary lesion characteristics.     

小儿石灰粉吸入性异物致呼吸衰竭救治成功一例

患儿男,1岁8个月.因咳喘、气促半天于2007年11月5日入院.入院前1天患儿不慎跌入石灰池中,半天后出现咳喘,气促伴呕吐,并渐进性加重,急来我院.入院时主要临床表现:头面部见紫红色淤斑点,神志模糊,精神萎糜,呼吸困难,吸气性三凹征明显;体温39℃,呼吸40～50次/min,双肺呼吸音粗,可闻湿啰音,右肺呼吸音减低,心率150～170次/min,律齐,无杂音.     

吸烟女性异丙酚无痛人工流产麻醉效果观察

目的　探讨吸烟对无痛人流术中麻醉药物异丙酚用量及镇痛效果的影响。方法　 10 2例实施无痛人流术患者分为吸烟组及非吸烟组 ,观察两组患者异丙酚用量及麻醉效果 ,并进行分析。结果　有吸烟习惯的患者术中异丙酚用量明显增加 (P <0 .0 1) ,且麻醉效果较对照组差。结论　异丙酚的镇痛作用受吸烟因素影响 ,吸烟者较不吸烟者需用更多的镇痛药物方能达到理想效果。     

无创持续气道正压通气治疗睡眠呼吸暂停综合征的护理

无创持续气道正压通气是目前治疗睡眠呼吸暂停综合征的不开刀、最简单有效的方法。我科自2002年5月1日～2005年12月31日,采用此方法共治疗了136例患者,取得了良好的效果。现将护理体会介绍如下。1治疗前护理心理护理:由于患者此前从未见过、使用过呼吸机,一听到呼吸机以为是频死患者才用的抢救器材,普遍存在恐惧心理。首先,护士必须尊重患者,对其提出的问题要耐心细致地解释,详细介绍呼吸机治疗既不要插管也不要气管切开,是用面罩安在鼻子上进行正压通气,给于气道一定压力,无创伤、无痛苦、简单有效,并且介绍同种疾病的治疗情况,减轻其恐惧…     

放射性核素血浆标本法肾小球滤过率测定的质量控制

肾小球滤过率(GFR)是检测肾脏滤过功能的一项重要指标,但除了肾功能水平外GFR受很多因素影响.我科于1995年起采用国际上推荐的双血浆标本法测定GFR[1],本文对影响该方法的因素包括99Tcm-DTPA 注射剂量、不同条件下测定CPM、性别及体表面积等进行了质量控制方面的探讨,报告如下.