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41.
用高速离心、分段盐析、亲和层析、超滤和阴离子交换层析法,从牛胎盘中分离纯化出一种肝细胞生长因子。结果表明,此因子的最终得率为0.005mg/g牛胎盘,其分子量约为99000u,它能强烈刺激原代培养大鼠肝细胞的DNA合成。提示利用自制的亲和层析凝胶,通过此提纯流程可以得到一种肝细胞生长因子。 相似文献
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选择性髂内动脉结扎与栓塞对盆腔血供的影响 总被引:5,自引:0,他引:5
目的:旨在探讨选择性髂内动脉结扎与栓塞两种方法对盆腔血供的影响。方法:将两组犬在膀胱上动脉分支以下之髂内动脉分别行结扎与栓塞,对比观察两组膀胱创面出血、盆腔动脉造影及盆腔脏器组织学变化,以确定其盆腔脏器的血供情况。结果:①结扎组膀胱创面出血明显大于栓塞组;②结扎组髂内动脉侧支循环建立时间明显早于且数目多于栓塞组;③两组盆腔脏器均未见缺血坏死。结论:栓塞组阻断髂内动脉侧支循环的数目多于结扎组,故对盆腔血供的影响大于结扎组。避免髂内动脉阻断范围过广可减少盆腔脏器缺血坏死的机会。 相似文献
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S J Dwyer B K Stewart J W Sayre D R Aberle M I Boechat J C Honeyman J M Boehme H Roehrig T L Ji G J Blaine 《Radiographics》1992,12(4):765-772
Gray-scale monitors are an essential element of electronic radiology, and their ability to provide images that are perceived to be identical to those available on conventional or laser-printed film is crucial to success of electronic radiology. Image fidelity is measured in physical characteristics (luminance, dynamic range, distortion, resolution, and noise) and with psychophysical techniques, including receiver operator characteristics analysis with clinical images and testing with contrast-detail patterns to determine threshold contrast. Currently, laser-printed images facilitate greater information transfer than does a gray-scale monitor because of their higher absolute luminance (500 ft-L vs 60 ft-L), greater perceived dynamic range, and better spatial resolution. In the near future, the developments of gray-scale monitors with 150-200 ft-L luminance, a display standard based on just noticeable differences, and algorithms to improve similarities between gray-scale display images and laser-printed images will help increase the acceptability of monitors as a means to make primary diagnoses. 相似文献
46.
在现代化医院面临国内国际竞争时,医院双语服务摆到了医院管理者的议事日程上来。医院双语服务,特别是医院外语(英语)标识应采用国际化、标准化外语(英语)。医院使用双语标识时应注意几个问题: 相似文献
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S H Jee S Y Won J E Yun J E Lee J S Park S S Ji 《International journal of gynaecology and obstetrics》2004,85(3):301-308
OBJECTIVES: Although some studies have reported that the arginine isoform on codon 72 of p53 increases the susceptibility to invasive cervical cancer, such data remain controversial. The objective of this study was to quantitatively summarize the evidence for such a relationship. METHODS: Our data sources consisted of a MEDLINE search of the literature published before December 2002, bibliography review, and expert consultation. Thirty-seven studies met the inclusion criteria. Information on sample size, study design, Hardy-Weinberg equilibrium, and method of genotype determination was abstracted by two reviewers using a standardized protocol. The overall odds ratio (OR) of the p53 gene on invasive cervical cancer was estimated using the Mantel-Haenzel method. RESULTS: The overall OR (95% confidence interval) for cervical cancer among those with the homozygous mutant (Arg/Arg) was 1.2 (1.1-1.3, P=0.001) compared with those with the heterozygous mutant (Arg/Pro). By a cellular type of cervical cancer, the overall OR among those with Arg/Arg was statistically significant in adenocarcinomas (1.7, 1.1-2.6, P=0.024), but not in squamous cell carcinomas (1.1, 0.9-1.2, P=0.960), compared with Pro/Pro. Compared with Arg/Pro, the OR among those with Arg/Arg was statistically significant in HPV types 16 (1,5, 1.2-2.0, P=0.002). CONCLUSIONS: Overall, the p53 gene was associated with increased risk for invasive cervical cancer. However, the risk varied by country, cellular, and HPV type. 相似文献
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Yong Kim R Bruce Donoff David T W Wong Randy Todd 《Journal of oral and maxillofacial surgery》2002,60(8):924-930
Information determining cellular structure and function is contained in chromosomal DNA. Genes, regions of DNA encoding this information, are composed of specific sequences of nucleotides. DNA sequencing methods have been developed to identify these sequences. Even subtle alteration (or mutation) of these sequences can lead to many human syndromes and diseases. This article reviews 1) the structure of the nucleotide, 2) the methods of DNA sequencing, and 3) its recent clinical application in analysis of the nevoid basal cell carcinoma syndrome. 相似文献
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