应用核酸分子杂交技术检测心肌炎组织中的肠道病毒RNA

用生物素标记ｐＣＢＩＩＩ／３５和ｐＣＢＩＩＩ／５１肠道病毒属特异性探针，对４５心肌炎和心肮病尸检或心肌活检心脏组织进行原位杂交，结果显示：１２例（２６．６％）存在肠道病毒ＲＮＡ。柯萨基Ｂ３病毒型特异性探针ｐＣＢＩＩＩ／２９进一步杂交表明，１２例经证实存在肠道病毒ＲＮＡ的心肌组织中５例（４１．７％）出现阳性杂交信号。阳性杂信号主要位于单个或多个心肌细胞的胞浆和心肌的间质组织，偶见竽心肌小血管内皮细胞     

降纤酶治疗青年人短暂性脑缺血发作的临床研究

目的 探讨降纤酶对青年人短暂性脑缺血（ＴＩＡ）发作的治疗效果。方法 将７２例患者随机分为两组。治疗组３７例,给予降纤酶静滴至ＴＩＡ发作终止或治疗达１周;对照组３５例,给予阿司匹林、尼莫地平、低分子右旋糖酐、脉络宁治疗２周。两组于治疗前、后分别采静脉血检测血浆纤维蛋白原、红细胞压积、全血粘度和血浆粘度的变化。结果 总有效率治疗组为９１．６６％,对照组为７７．１４％,２组间有显著性差异（Ｐ〈０．０１）     

医学大学生对医德认知的调查研究

采用抽样研究方法,对４３８名不同专业、不同层次的大学生进行了医德认知调查,以了解大学生对医德基本知识掌握的情况,结果表明,大学生对开设医学伦理学课必要性认识均率为６２．９％,课外经常阅读医德书籍均率为２２．７５％,对中外基德发展史各朝代典型的人物及代表作了解的均率为３１．１％,文中对调查结果进行了分析。     

Effects of reciprocal treatment with estrogen and estrogen plus parathyroid hormone on bone structure and strength in ovariectomized rats.

Intermittent administration of PTH has been found to be an effective anabolic agent in cancellous bone. We have reported previously that combined treatment with PTH and estrogen in estrogen-deficient rats was beneficial in correcting established osteopenia. To determine if the beneficial effects of PTH therapy can be preserved by estrogen alone and whether PTH therapy can be effective in treating osteopenic subjects stabilized with estrogen, we have undertaken a "crossover" study in the rat model of estrogen-deficiency induced osteopenia. Six-month-old female rats were ovariectomized and after 5 wk treated for 8 wk with vehicle, 30 micrograms/kg per day of rPTH(1-34) plus 15 micrograms/kg per day of 17 beta-estradiol or 17 beta-estradiol alone. One group from each treatment regimen was then sacrificed and for an additional 8 weeks the remaining rats were (a) maintained on their previous treatment; (b) "crossed over" to their reciprocal treatment; or (c) administered vehicle only. At the end of this second 8-wk treatment period all rats were sacrificed. Bone mineral density of the distal femur, histomorphometric measurements of the proximal tibia and mechanical testing of the distal femur and selected vertebral bodies were performed. Our results demonstrated that (a) the gains in bone mass, trabecular connectivity and mechanical strength induced by PTH can be maintained by estrogen alone, but are reversed when both agents are withdrawn; and (b) rats with established osteopenia, maintained on estrogen treatment alone, can derive the full beneficial effects from the addition of PTH to the treatment at a later date. These data indicate that combined and/or sequential use of antiresorptive and anabolic agents may be a promising approach to the treatment of osteoporosis.     

An outline of spreading of Western mediciine into Yantai in modern age

At the turn of the last century, side by side with the infiltration of religious culture from Western countries, western medicine spread into Yantai. The religious force, headed by American Presbyterian Mission, carried out charitable activities in the process of preaching and laid down the foundation for western medicine rooted in Yantai by establishing schools, education and training followers. They cultivated local physicians by first setting up clinics which had later transformed into hospitals. These are their major measures for building bases for spreading Christianity by foreigners. The Temple Hill Hospital set up by the American physician Oscar F. Hills in Yantai was a successful example of mutual promotion of missionary and medical activities which pushed forward the spreading and development of western medicine in Yantai.     

Is episodic obsessive compulsive disorder bipolar? A report of four cases

Several reports have noted cases of OCD which were unusual in showing an abrupt remission. We report longitudinal clinical observation of four cases of acute onset OCD without major depression through a variety of treatments. These patients had prominent feelings of shamefulness; compared to patients with typical OCD they were ill for months rather than years and were older. Two had previous episodes of psychiatric illness with full recovery. Full and persistent recovery occurred in response to lithium or an acute course of ECT but not to tricyclic or SSRI antidepressants. The generalizability of these observations is limited by its uncontrolled nature and the small numbers. The courses observed were consistent with episodic OCD as a possible expression of bipolar disorder and consideration of corresponding treatments. This perspective offers a new rationale for reported observations of remissions of acute onset OCD in response to lithium without lithium effectiveness for typical OCD.     

肿瘤标志物DR-70在恶性肿瘤诊断中的应用

目的：评价肿瘤标志物ＤＲ－７０在恶性肿瘤中的诊断应用。方法：应用美国ＡＭＤＬ公司的ＤＲ－７０＾ＴＭ ＥＬＩＳＡ试剂盒,测定对２０例正常人和５９例恶性肿瘤病人血清ＤＲ－７０含量。结果：各种恶性肿瘤ＤＲ－７０的阳性率为６６．７￣１００％,均较正常对照组有非常显著性差异（Ｐ〈０．００１）。结论：血清ＤＲ－７０是诊断恶性肿瘤有价值的标志物。     

以零价铜为催化剂的“活性”可控自由基聚合反应

研究了零价铜为催化剂,以ＣＣｌ４为引发剂,在２,２’－邻二吡啶（ｂｐｙ）或１,１０－邻二氮菲（ｐｈｅｎ）存在下的苯乙烯或甲基丙烯酸甲酯的“活性”／可控自由基聚合反应。研究结果表明：聚合过程中ｌｎ（［Ｍ］ｏ／［Ｍ］）与反应时间成线性增长关系,同时生成的聚合物的数均分子量与单体转化率也成线性增长关系,聚合过程呈现“活性”特征。     

小儿急性中毒77例临床分析及预防

本文对近 10年收治 77例急性中毒的患儿进行了回顾性分析。观察到 :年幼小儿、农村小儿发病率较高 ,因误服药物、鼠药的食物致急性中毒的患儿较多 ,死亡病例均因就诊太晚。提示 :对急性中毒必须早诊断、早治疗。并提出减少小儿意外中毒的关键应从预防着手     

臂丛下干的应用解剖观察

目的了解斜角肌间隙内臂丛下干与邻近组织结构及胸１神经干与第１肋的关系,为临床诊治臂丛下干卡压症提供解剖学依据。②方法在２１具４２侧成人标本上观测臂丛下干与邻近结构的位置关系。③结果在４２侧标本的斜角肌间隙内,有３３侧在前斜角肌的后内侧存在孤立的肌束,臂丛下干分别从其前下方（２３侧）或后上方（１０侧）通过;组成臂丛下干的胸１神经干在斜越第１肋前内侧面时部分穿行于骨纤维管内。④结论该肌束的压迫或拱抬均可成为臂丛下干受压的因素之一;组成臂丛下干的胸１神经干在越过第１肋时易受压迫。