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排序方式: 共有1027条查询结果,搜索用时 15 毫秒
31.
Yoshiya Yamamoto Takahiro Ohara Akira Funada Hiroyuki Takahama Makoto Amaki Takuya Hasegawa Yasuo Sugano Hideaki Kanzaki Toshihisa Anzai 《Journal of Echocardiography》2016,14(1):39-41
A 66-year-old female, under regular follow-up for 20 years after aortic valve replacement (19-mm Carbomedics), presented dyspnea on effort and hypotension during hemodialysis. A transthoracic echocardiogram showed elevation of transvalvular velocity up to 4 m/s, but the structure around the aortic prosthesis was difficult to observe due to artifacts. Fluoroscopy revealed normal motion of the leaflets of the mechanical valve. Intracardiac echocardiography (ICE) revealed a pannus-like structure in the left ventricular outflow tract. Transesophageal echocardiogram also revealed this structure. ICE can visualize structural abnormalities around a prosthetic valve after cardiac surgery even in patients in whom conventional imaging modalities failed. 相似文献
32.
Hiroyuki?Takahama Masanori?Asakura Yukio?Abe Masayoshi?Ajioka Kazutaka?Aonuma Toshihisa?Anzai Takaharu?Hayashi Shinya?Hiramitsu Hiroya?Kawai Hidetaka?Kioka Kazuo?Kimura Young-Jae?Lim Ken?Matsuoka Hirohiko?Motoki Yoji?Nagata Sunao?Nakamura Nobuyuki?Ohte Yukio?Ozaki Taishi?Sasaoka Shunsuke?Tamaki Toshimitsu?Hamasaki Masafumi?Kitakaze 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》2018,32(4):381-388
Background
Previous studies suggest that the pathophysiology of heart failure with preserved ejection fraction (HFpEF) is characterized not only by high ventricular stiffness, but also by vascular stiffness. Azilsartan has higher vascular affinity compared with other angiotensin II receptor blockers (ARBs), which were proven to have no beneficial effects on clinical outcomes in patients with HFpEF in earlier clinical trials. We aimed to test the hypothesis that azilsartan may improve left ventricular diastolic function in HFpEF patients with hypertension in this trial.Methods
The Effects of Angiotensin Receptor Blockers on Diastolic Function in Patients Suffering from Heart Failure with Preserved Ejection Fraction: J-TASTE trial is a multicenter, randomized, open-labeled, and assessor(s)-blinded, active controlled using candesartan, parallel-group clinical trial, to compare changes in left ventricular (LV) diastolic dysfunction between HFpEF patients with hypertension who have received candesartan or azilsartan for 48 weeks. The primary endpoint is the change in early diastolic wave height/early diastolic mitral annulus velocity (E/e’) assessed by echocardiography from the baseline to the end of the study (48 weeks). A total of 190 patients will be recruited into the study.Conclusions
The design of the J-TASTE trial will provide data on whether differences between the effects of the two tested drugs on LV diastolic function exist in HFpEF patients with hypertension and will improve understanding of the pathophysiological role of vascular stiffness on diastolic function.33.
Gastric cancer with metastasis to the gingiva 总被引:3,自引:0,他引:3
Shimoyama S Seto Y Aoki F Ogawa T Toma T Endo H Itouji T Kaminishi M 《Journal of gastroenterology and hepatology》2004,19(7):831-835
The present case report describes a gastric cancer which showed unusual metastasis in the oral region. A 56-year-old male patient underwent total gastrectomy and splenectomy due to advanced gastric cancer in the upper third of the stomach. Fifteen months later, he presented with anorexia and gingival swelling of durations of approximately 3 and 1 month, respectively. The gastric tumor was histologically a signet ring cell and a poorly differentiated cancer with a moderate degree of vascular invasion. Biopsy specimens from the gingival tumor revealed a signet ring cell cancer. Other metastatic sites were the brain, limb bones and abdominal lymph nodes. A bone scintigram revealed an abnormal uptake in the limb bones, while it did not exhibit any abnormality in the oral region. Correlation between the histology of the gingival tumor with that of the gastric cancer, as well as the absence of a gingival tumor at the time of prior gastrectomy, led to a diagnosis that the gingival tumor was a metastasis from gastric cancer. Gastric cancer metastasizing to the oral region, either the osseus or the oral soft tissue, is very rare. Although it cannot be proved without an autopsy, negative findings in the mandible by bone scanning in the present case suggest that direct gingival metastasis can be considered, rather than mandibular metastasis involving the gingiva. Hematogenous spread could be a mechanism of metastasis for this unusual tumor. 相似文献
34.
35.
Takashi Morihara Noriyuki Hayashi Mikiko Yokokoji Hiroyasu Akatsu Michael A. Silverman Nobuyuki Kimura Masahiro Sato Yuhki Saito Toshiharu Suzuki Kanta Yanagida Takashi S. Kodama Toshihisa Tanaka Masayasu Okochi Shinji Tagami Hiroaki Kazui Takashi Kudo Ryota Hashimoto Naohiro Itoh Kouhei Nishitomi Yumi Yamaguchi-Kabata Tatsuhiko Tsunoda Hironori Takamura Taiichi Katayama Ryo Kimura Kouzin Kamino Yoshio Hashizume Masatoshi Takeda 《Proceedings of the National Academy of Sciences of the United States of America》2014,111(7):2638-2643
36.
Asai Shuji Takahashi Nobunori Terabe Kenya Sobue Yasumori Nishiume Tsuyoshi Suzuki Mochihito Yokota Yutaka Ishiguro Naoki Kojima Toshihisa 《Clinical rheumatology》2020,39(11):3331-3339
Clinical Rheumatology - Periarticular osteophyte formation is observed during the repair of damaged joints in rheumatoid arthritis (RA); however, little is known about its clinical and functional... 相似文献
37.
Kazuhiro Ota Shimpei Kawaguchi Taro Iwatsubo Shinya Nishida Hironori Tanaka Yosuke Mori Noriyuki Nakajima Akitoshi Hakoda Noriaki Sugawara Yuichi Kojima Toshihisa Takeuchi Masahiro Sakaguchi Kazuhide Higuchi 《Internal medicine (Tokyo, Japan)》2022,61(3):335
A 77-year-old man complained of postmeal vomiting and sustained general fatigue. An abdominal computed tomography scan showed massive gastric expansion and fluid storage. Gastroscopy revealed four gastric bezoars that were considered to have caused pyloric ring obstruction. The patient was asked to drink 500 mL per day of Coca-ColaⓇ for 4 days. On the fourth day, we performed endoscopic crushing and removal by injecting Coca-ColaⓇ, cutting the softened bezoar with endoscopic snares, and collecting the pieces with endoscopic nets. We herein report (with a video presentation) a rare case of tannin-phytobezoars endoscopically removed with the administration and injection of Coca-ColaⓇ. 相似文献
38.
39.
Clinical impact of the presence of macrophages in endomyocardial biopsies of patients with dilated cardiomyopathy 下载免费PDF全文