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991.
992.
Human parvovirus B19 (HPV-B19), a small and non-enveloped DNA virus, causes erythema infectiosum (EI) in children. In adults, however, it is known to cause a variety of symptoms. A 39-year-old woman visited our hospital because of low-grade fever, diarrhea, bilateral leg edema, and numbness in the right arm, one and a half months after her daughter developed EI. We diagnosed her as HPV-B19 infection after her daughter's history and positive test for serum HPV-B19 IgM antibody, together with the continued observations. Two weeks later, she developed dizziness and left hearing difficulty. However, we did not give her any medication. HPV-B19 IgM antibody value (2.4) measured after one month of the onset was decreased to 1.7, 1.1, and 0.9 after two, three, and five months of the onset, respectively. Thus, it took 5 months for the IgM antibody value to become negative. Her symptoms gradually improved along with the decrease in HPV-B19 antibody without any medication. Hearing difficulty and dizziness are not categorized as manifestations of HPV-B19 infection, because these symptoms are very rare. The present report indicates that the symptoms related to inner ear dysfunctions should be added to those associated with adult HPV-B19 infection. In conclusion, we should consider HPV-B19 infection when we evaluate patients with causeless hearing difficulty and dizziness. 相似文献
993.
994.
995.
Nakamura T Hasegawa-Nakamura K Sakoda K Matsuyama T Noguchi K 《European journal of oral sciences》2011,119(5):345-351
The renin-angiotensin system is thought to be involved in inflammatory processes such as periodontitis. However, its precise role is still unclear. Therefore, in the present study the expression of the angiotensin II type 1 receptor (AT1R) was investigated in inflamed human gingival tissue, and the possible involvement of the AT1R in interleukin-1β (IL-1β)-induced interleukin-6 (IL-6) production by cultured human gingival fibroblasts (HGFs) was also studied. Immunohistochemical staining revealed that inflammatory cells and fibroblast-like cells were positive for the AT1R. However, in healthy gingival tissue, AT1R staining was very weak. The levels of AT1R mRNA and AT1R protein increased in HGFs after stimulation with IL-1β. The levels of IL-1β-induced IL6 mRNA and IL-6 protein were significantly reduced in AT1R gene-silenced HGFs compared with control HGFs. The data suggest that the AT1R may be involved in the regulation of gingival inflammation by modulating IL-1β-induced IL-6 production in HGFs. 相似文献
996.
Yohei Takahashi Morio Matsumoto Tatsuki Karasugi Kota Watanabe Kazuhiro Chiba Noriaki Kawakami Taichi Tsuji Koki Uno Teppei Suzuki Manabu Ito Hideki Sudo Shohei Minami Toshiaki Kotani Katsuki Kono Haruhisa Yanagida Hiroshi Taneichi Atsushi Takahashi Yoshiaki Toyama Shiro Ikegawa 《Journal of orthopaedic research》2011,29(7):1055-1058
Adolescent idiopathic scoliosis (AIS) is a spinal deformity most commonly arising in apparently healthy girls around puberty. AIS has a strong genetic predisposition. Several genetic associations between AIS and single nucleotide polymorphisms (SNPs) have been reported; common SNPs in the genes for matrilin 1 (MATN1), melatonin receptor 1B (MTNR1B), tryptophan hydroxylase 1 (TPH1), and insulin‐like growth factor 1 (IGF1) are reported to be associated with AIS in Chinese. However, these associations have not been replicated so far. To confirm the associations, we compared these SNPs with AIS predisposition and curve severity in a population of Japanese females consisting of 798 AIS patients and 1,239 controls. All the subjects were genotyped using the PCR‐based Invader assay. We found no association of any of the SNPs with AIS predisposition or curve severity. Considering the statistical power and sample size of the present study, we concluded that these SNPs are not associated with either AIS predisposition or curve severity in Japanese. © 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 29: 1055–1058, 2011 相似文献
997.
Kawashita Y Iwata T Kanetaka K Ono S Kawahara Y Fujisawa H Yoshida T Miyahara S Eto S Kanematsu T 《Surgical laparoscopy, endoscopy & percutaneous techniques》2011,21(1):e54-e58
Laparoscopic hepatectomy provides the usual advantages of a minimally invasive surgery. This study presents a case of Fasciola hepatica infection that was successfully treated with laparoscopic hepatectomy. The patient was referred because of persistent fever and right hypochondralgia with a huge mass occupying the right lobe of the liver, which was detected by imaging analysis. Serologic tests indicated an F. hepatica infection. The patient underwent a laparoscopic resection because the anthelmintic agent, triclabendazole was not effective. During the surgical technique, 5 trocars were inserted. After liver mobilization, the Glissonian pedicles and right hepatic veins were safely taped. A Penrose drain was placed behind the liver for a liver-hanging maneuver. A liver parenchymal transection was performed through an 8 cm handport site using a dissecting sealer (TissueLink Medical) after precoagulating its superficial layer by microtaze. Glissonian pedicles and the right hepatic vein were divided using an endolinear stapler (endcutter 45, Ethicon). Finally, the resected specimen was extracted from the handport. The surgical time was 450 minutes and the surgical blood loss was 370 mL. The patient was discharged 10 days after the surgery with an uneventful postoperative course. The laparoscopy-assisted hepatectomy in this case was beneficial for the patient's quality of life as a minimally invasive operation with a high degree of safety. 相似文献
998.
999.
Takeshi Furukawa Masahiko Kishiro Hideo Fukunaga Masahiro Ohtsuki Ken Takahashi Katsumi Akimoto Toshiaki Shimizu Shiori Kawasaki Toshio Kumasaka 《Pediatric cardiology》2010,31(6):773-779
The outcome of stent implantation for pulmonary vein stenosis (PVS) in children remains poor. Several reports describe placing
drug-eluting stents to treat PVS, but their effectiveness remains unknown. In this study, three bare-metal stents (BMSs) and
three sirolimus-eluting stents (SESs) were implanted in 1-month-old pigs. The pigs were killed 8 weeks later to compare in-stent
stenosis rates. The extent of neointimal thickness, as measured by injury score, was significantly less in the SES group than
in the BMS group (injury score 1: BMS 0.351 ± 0.033 vs SES 0.226 ± 0.031 mm; P < 0.01; injury score 2: BMS 1.232 ± 0.244 vs SES 0.609 ± 0.208 mm; P < 0.01). The pathologic findings showed confluence of inflammatory cells around the stent wires in BMS-treated areas and
granuloma formation. Granuloma formation was not seen with SES. The degree of in-stent stenosis was significantly reduced
in the SES group, suggesting that the use of drug-eluting stents is an effective treatment for PVS. Because of the small sample
size and the considerable variation in injury scores and balloon-to-vein ratios, future studies with larger samples are necessary. 相似文献
1000.
Rumi Ohata Tadaharu Okazaki Yoichi Ishizaki Junya Fujimura Toshiaki Shimizu Geoffrey J. Lane Atsuyuki Yamataka Seiji Kawasaki 《Pediatric surgery international》2010,26(4):447-450
Pancreatoblastoma (PB) is extremely rare. A 11-year-old boy, who had excision of dilated common bile duct with hepaticoduodenostomy
when 9 years old was referred to our institute for further management of abdominal pain and steatorrhea. Imaging studies showed
a solid 4 cm tumor in the head of the pancreas and two lesions in the liver. Needle biopsies diagnosed PB with liver metastases.
After five courses of chemotherapy, the primary tumor was completely resected with pancreaticoduodenectomy (PD) and Child’s
pancreaticobiliary tract reconstruction. The liver metastases were resected. Postoperative recovery was uneventful. Here,
we present this case and review the literature focusing on management of PB. 相似文献