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排序方式: 共有439条查询结果,搜索用时 31 毫秒
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Kati Pasanen Jussi Hietamo Tommi Vasankari Pekka Kannus Ari Heinonen Urho M. Kujala Ville M. Mattila Jari Parkkari 《Journal of Science and Medicine in Sport》2018,21(3):268-273
Objectives
To investigate the incidence and characteristics of acute time-loss injuries in Finnish junior floorball league players.Design
Prospective cohort study with 3-year follow-up.Methods
One hundred and eighty-six female and male players (mean age 16.6 ± 1.4) took part in the follow-up study (2011–2014). The training hours and games were recorded on a team diary. Floorball related acute injuries were registered and verified by a research physician. The injury incidence was expressed as the number of injuries per 1000 h of exposure. Incidence rate was calculated separately for games and practices, and for males and females.Results
One hundred and forty-four acute time-loss injuries occurred. Injury incidence was 26.87 (95% CI 20.10–33.63) in junior league games, and 1.25 (95% CI 0.99–1.52) in team practices. Female players had significantly higher game injury rate (IRR 1.88, 1.12–3.19) and joint/ligament injury rate (IRR 1.70, 1.07–2.73) compared to males. Eighty-one percent of the injuries affected the lower limbs. The ankle (37%), knee (18%), and thigh (14%) were the most commonly injured body sites. More than half of injuries involved joint or ligaments (54%). Twenty-six percent of the injuries were severe causing more than 28 days absence from sports. Eight anterior cruciate ligament ruptures of the knee occurred among seven female players.Conclusion
The study revealed that risk of ankle and knee ligament injuries is high in adolescent floorball, specifically among female players. 相似文献74.
Krki Tommi Plachouras Diamantis Cassini Alessandro Suetens Carl 《Wiener Medizinische Wochenschrift》2019,169(1):3-5
Wiener Medizinische Wochenschrift - Point prevalence surveys of healthcare-associated infections (HAI) and antimicrobial use in the European Union and European Economic Area (EU/EEA) from 2016 to... 相似文献
75.
Anna Kuukasjrvi Juan C. Landoni Jyrki Kaukonen Mika Juhakoski Mari Auranen Tommi Torkkeli Vidya Velagapudi Anu Suomalainen 《European journal of human genetics : EJHG》2021,29(12):1833
The aetiology of dystonia disorders is complex, and next-generation sequencing has become a useful tool in elucidating the variable genetic background of these diseases. Here we report a deleterious heterozygous truncating variant in the inosine monophosphate dehydrogenase gene (IMPDH2) by whole-exome sequencing, co-segregating with a dominantly inherited dystonia-tremor disease in a large Finnish family. We show that the defect results in degradation of the gene product, causing IMPDH2 deficiency in patient cells. IMPDH2 is the first and rate-limiting enzyme in the de novo biosynthesis of guanine nucleotides, a dopamine synthetic pathway previously linked to childhood or adolescence-onset dystonia disorders. We report IMPDH2 as a new gene to the dystonia disease entity. The evidence underlines the important link between guanine metabolism, dopamine biosynthesis and dystonia.Subject terms: Movement disorders, Disease genetics 相似文献
76.
Episodic memory is thought to rely on interactions of the hippocampus with other regions of the distributed hippocampal‐cortical network (HCN) via interregional activity synchrony in the theta frequency band. We sought to causally test this hypothesis using network‐targeted transcranial magnetic stimulation. Healthy human participants completed four experimental sessions, each involving a different stimulation pattern delivered to the same individualized parietal cortex location of the HCN for all sessions. There were three active stimulation conditions, including continuous theta‐burst stimulation, intermittent theta‐burst stimulation, and beta‐frequency (20‐Hz) repetitive stimulation, and one sham condition. Resting‐state fMRI and episodic memory testing were used to assess the impact of stimulation on hippocampal fMRI connectivity related to retrieval success. We hypothesized that theta‐burst stimulation conditions would most strongly influence hippocampal‐HCN fMRI connectivity and retrieval, given the hypothesized relevance of theta‐band activity for HCN memory function. Continuous theta‐burst stimulation improved item retrieval success relative to sham and relative to beta‐frequency stimulation, whereas intermittent theta‐burst stimulation led to numerical but nonsignificant item retrieval improvement. Mean hippocampal fMRI connectivity did not vary for any stimulation conditions, whereas individual differences in retrieval improvements due to continuous theta‐burst stimulation were associated with corresponding increases in fMRI connectivity between the hippocampus and other HCN locations. No such memory‐related connectivity effects were identified for the other stimulation conditions, indicating that only continuous theta‐burst stimulation affected memory‐related hippocampal‐HCN connectivity. Furthermore, these effects were specific to the targeted HCN, with no significant memory‐related fMRI connectivity effects for two distinct control brain networks. These findings support a causal role for fMRI connectivity of the hippocampus with the HCN in episodic memory retrieval and indicate that contributions of this network to retrieval are particularly sensitive to continuous theta‐burst noninvasive stimulation. 相似文献
77.
78.
Ahola P Valkonen-Korhonen M Tolmunen T Joensuu M Lehto SM Saarinen PI Tiihonen J Lehtonen J 《American journal of psychotherapy》2011,65(4):355-379
The perceptions of patients (n = 25) and their therapists about psychodynamic psychotherapy for depression were assessed during the first treatment year using 23 scales. Patients and therapists independently evaluated the impact of depression on the therapeutic experience of the patients. The estimations of the impact of depression by the patients and therapists were concordant in the majority of the subjects, reflecting mutual tuning and a working alliance. The roles of affects and frustrating subjects in the treatment relationship were evaluated as significantly different by the patients and the therapists. The results highlight the importance of working on the expression of affects in the psychotherapy of depression. 相似文献
79.
Kwon MS Vorobyev V K?nn?l? S Laine M Rinne JO Toivonen T Johansson J Ter?s M Lindholm H Alanko T H?m?l?inen H 《Journal of cerebral blood flow and metabolism》2011,31(12):2293-2301
We investigated the effects of mobile phone radiation on cerebral glucose metabolism using high-resolution positron emission tomography (PET) with the (18)F-deoxyglucose (FDG) tracer. A long half-life (109 minutes) of the (18)F isotope allowed a long, natural exposure condition outside the PET scanner. Thirteen young right-handed male subjects were exposed to a pulse-modulated 902.4 MHz Global System for Mobile Communications signal for 33 minutes, while performing a simple visual vigilance task. Temperature was also measured in the head region (forehead, eyes, cheeks, ear canals) during exposure. (18)F-deoxyglucose PET images acquired after the exposure showed that relative cerebral metabolic rate of glucose was significantly reduced in the temporoparietal junction and anterior temporal lobe of the right hemisphere ipsilateral to the exposure. Temperature rise was also observed on the exposed side of the head, but the magnitude was very small. The exposure did not affect task performance (reaction time, error rate). Our results show that short-term mobile phone exposure can locally suppress brain energy metabolism in humans. 相似文献
80.
Petro Julkunen Esa P. Halmesmäki Jarkko Iivarinen Lassi Rieppo Tommi Närhi Juho Marjanen Jarno Rieppo Jari Arokoski Pieter A. Brama Jukka S. Jurvelin Heikki J. Helminen 《Journal of anatomy》2010,217(3):262-274
Articular cartilage composition and structure are maintained and remodeled by chondrocytes under the influence of loading. Exercise‐induced changes in the composition, structure, mechanical properties and tissue integrity of growing and aging hamster articular cartilage were investigated. Articular cartilage samples (n = 191) were harvested from the proximal tibiae of hamsters aged 1, 3, 6, 12 and 15 months. The hamsters were divided into runners and controls. The runners had free access to a running wheel between 1 and 3 months (runner groups 3‐, 12‐ and 15‐month‐old hamsters) or 1 and 6 months (runner group 6‐month‐old hamsters) of age. Control animals were subjected to a sedentary lifestyle. Mechanical indentation tests and depth‐wise compositional and structural analyses were performed for the cartilage samples. Furthermore, the integrity of articular cartilage was assessed using histological osteoarthritis grading. Exercise affected the collagen network organization after a 5‐month exercise period, especially in the middle and deep zones. However, no effect on the mechanical properties was detected after exercise. Before the age of 12 months, the runners showed less osteoarthritis than the controls, whereas at 15 months of age the situation was reversed. It is concluded that, in hamsters, physical exercise at a young age enhances cartilage maturation and alters the depth‐wise cartilage structure and composition. This may be considered beneficial. However, exercise at a young age demonstrated adverse effects on cartilage at a later age with a significant increase in the incidence of osteoarthritis. 相似文献