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排序方式: 共有6116条查询结果,搜索用时 250 毫秒
121.
Carla Palleis MD Julia Sauerbeck Leonie Beyer MD Stefanie Harris Julia Schmitt Estrella Morenas-Rodriguez PhD Anika Finze Alexander Nitschmann Francois Ruch-Rubinstein Florian Eckenweber Gloria Biechele Tanja Blume MSc Yuan Shi PhD Endy Weidinger MD Catharina Prix MD Kai Bötzel MD Adrian Danek MD Boris-Stephan Rauchmann MD Sophia Stöcklein MD Simon Lindner PhD Marcus Unterrainer MD Nathalie L. Albert MD Christian Wetzel PhD Rainer Rupprecht MD Axel Rominger MD Peter Bartenstein MD Jochen Herms MD Robert Perneczky MD Christian Haass PhD Johannes Levin MD Günter U. Höglinger MD Matthias Brendel MD 《Movement disorders》2021,36(4):883-894
122.
Stefanie J.G. Veenhuis MD Nienke J.H. van Os MD PhD Anjo J.W.M. Janssen PhD Marjo H.J.C. van Gerven MSc Karlien L.M. Coene PhD Udo. F.H. Engelke PhD Ron A. Wevers PhD Gerjen H. Tinnevelt PhD Rob ter Heine PhD Bart P.C. van de Warrenburg MD PhD Corry M.R. Weemaes MD PhD Nel Roeleveld PhD Michèl A.A.P. Willemsen MD PhD 《Movement disorders》2021,36(12):2951-2957
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124.
Koop Barbara Elisabeth Mayer Felix Gündüz Tanju Blum Jacqueline Becker Julia Schaffrath Judith Wagner Wolfgang Han Yang Boehme Petra Ritz-Timme Stefanie 《International journal of legal medicine》2021,135(1):167-173
International Journal of Legal Medicine - Age estimation based on the analysis of DNA methylation patterns has become a focus of forensic research within the past few years. However, there is... 相似文献
125.
Bohnert Simone Reinert Christoph Trella Stefanie Schmitz Werner Ondruschka Benjamin Bohnert Michael 《International journal of legal medicine》2021,135(1):183-191
International Journal of Legal Medicine - In the last few years, quantitative analysis of metabolites in body fluids using LC/MS has become an established method in laboratory medicine and... 相似文献
126.
127.
128.
Rues Stefan Schmitter Marc Kappel Stefanie Sonntag Robert Kretzer Jan Philippe Nadorf Jan 《Clinical oral investigations》2021,25(3):1265-1272
Clinical Oral Investigations - Conventional dental implants inserted in the molar region of the maxilla will reach into the sinus maxillaris when alveolar ridge height is limited. When surgery is... 相似文献
129.
Melanie Merswolken Hans-Christian Deter Sabine Siebenhuener Kristina Orth-Gomér Cora Stefanie Weber 《International journal of behavioral medicine》2013,20(3):461-467
Background
Anxiety is associated with worse outcomes in patients with coronary heart disease (CHD). A dysregulation of the HPA axis is a potential mechanism linking psychological factors and coronary disease. No study has yet investigated the relationship between anxiety and cortisol among patients with established CHD.Purpose
The aim of this study was to assess the association between anxiety and the cortisol awakening response in patients with CHD.Method
Four salivary cortisol samples were used to assess two measures of the cortisol awakening response (CAR) in 47 patients with established CHD. Anxiety was measured using the Hospital Anxiety and Depression Scale (HADS).Results
Higher anxiety values were associated with a higher total output of cortisol in the first hour after awakening (AUCg, area under the curve with respect to ground) (p?=?0.04) and a nonsignificant trend towards a more pronounced increase (AUCi, area under the curve with respect to increase) (p?=?0.08). In patients who had a history of myocardial infarction (MI), the cortisol output was lower compared to patients who had no previous MI (p?=?0.02). In linear regression analyses, anxiety emerged as significant predictor of AUCg and AUCi after controlling for MI, ejection fraction (LVEF, left ventricular ejection fraction), and depression.Conclusions
Our results provide further indications for an association between anxiety and a dysregulation of the HPA axis. History of MI emerged as second predictor of cortisol output in the morning. 相似文献130.
Yael Lupu-Haber Oded Pinkas Stefanie Boehm Thomas Scheper Cornelia Kasper Marcelle Machluf 《Biomedical microdevices》2013,15(6):1055-1066
Bone tissue engineering is an alternative approach to bone grafts. In our study we aim to develop a composite scaffold for bone regeneration made of doped zirconium oxide (ZrO2) conjugated with poly(lactic-co-glycolic acid) (PLGA) particles for the delivery of growth factors. In this composite, the PLGA microspheres are designed to release a crucial growth factor for bone formation, bone morphogenetic protein-2 (BMP2). We found that by changing the polymer’s molecular weight and composition, we could control microsphere loading, release and size. The BMP2 released from PLGA microspheres retained its biological activity and increased osteoblastic marker expression in human mesenchymal stem cells (hMSCs). Uncapped PLGA microspheres were conjugated to ZrO2 scaffolds using carbodiimide chemistry, and the composite scaffold was shown to support hMSCs growth. We also demonstrated that human umbilical vein endothelial cells (HUVECs) can be co-cultured with hMSCs on the ZrO2 scaffold for future vascularization of the scaffold. The ZrO2 composite scaffold could serve as a bone substitute for bone grafting applications with the added ability of releasing different growth factors needed for bone regeneration. 相似文献