全文获取类型
收费全文 | 23608篇 |
免费 | 417篇 |
国内免费 | 43篇 |
专业分类
耳鼻咽喉 | 693篇 |
儿科学 | 494篇 |
妇产科学 | 2051篇 |
基础医学 | 3298篇 |
口腔科学 | 985篇 |
临床医学 | 801篇 |
内科学 | 4030篇 |
皮肤病学 | 778篇 |
神经病学 | 2098篇 |
特种医学 | 339篇 |
外科学 | 2348篇 |
综合类 | 106篇 |
一般理论 | 1篇 |
预防医学 | 1633篇 |
眼科学 | 1057篇 |
药学 | 2754篇 |
中国医学 | 30篇 |
肿瘤学 | 572篇 |
出版年
2022年 | 262篇 |
2021年 | 466篇 |
2020年 | 134篇 |
2019年 | 221篇 |
2018年 | 398篇 |
2017年 | 265篇 |
2016年 | 287篇 |
2015年 | 328篇 |
2014年 | 509篇 |
2013年 | 678篇 |
2012年 | 866篇 |
2011年 | 992篇 |
2010年 | 505篇 |
2009年 | 287篇 |
2008年 | 602篇 |
2007年 | 802篇 |
2006年 | 909篇 |
2005年 | 821篇 |
2004年 | 920篇 |
2003年 | 901篇 |
2002年 | 763篇 |
2001年 | 689篇 |
2000年 | 676篇 |
1999年 | 568篇 |
1998年 | 176篇 |
1992年 | 372篇 |
1991年 | 328篇 |
1990年 | 359篇 |
1989年 | 414篇 |
1988年 | 468篇 |
1987年 | 452篇 |
1986年 | 459篇 |
1985年 | 436篇 |
1984年 | 350篇 |
1983年 | 257篇 |
1979年 | 528篇 |
1978年 | 316篇 |
1977年 | 257篇 |
1976年 | 246篇 |
1975年 | 343篇 |
1974年 | 512篇 |
1973年 | 515篇 |
1972年 | 431篇 |
1971年 | 409篇 |
1970年 | 388篇 |
1969年 | 409篇 |
1968年 | 355篇 |
1967年 | 274篇 |
1966年 | 291篇 |
1965年 | 176篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
D Karczewicz T Baranowska-George O Palacz E Tokarz-Sawińska W Stankiewicz Z Krzystolik W Lubiński K Ko?mider 《Klinika oczna》1989,91(1):9-11
Presented are the results of examination of 75 men, workers of the Chemical Works in Police, in whom in the scheme of complex clinical examinations detailed ophthalmological examinations have been carried out. The period of a professional contact with fluor amounted 6-15 years. The examined persons showed a variety of changes; the most important were opacities of the lens capsule, attenuation of the retinal arteries and a pathological record of the ERG. 相似文献
42.
Micha? Ciurzyński Piotr Bienias Agnieszka Szewczyk Barbara Lichodziejewska Maria B?aszczyk Danuta Liszewska-Pfejfer Piotr Pruszczyk 《Medical science monitor》2007,13(10):CS124-CS127
BACKGROUND: Systemic sclerosis (SSc) is a connective tissue disorder of unknown etiology characterized by fibrosis of the skin and visceral organs, in which the heart is frequently (40-70% of patients) and severely involved. Pulmonary hypertension affects 10-15% of patients with SSc and is one of the most important complications adversely influencing their survival. CASE REPORT: The case report presents a 59-year-old male patient with advanced systemic sclerosis whose initial examination revealed pulmonary hypertension, rhythm and atrioventricular conduction disturbances, and elevated level of NT-proBNP. After six months the patient deteriorated; an increase in NT-proBNP level and progression of pulmonary hypertension were observed. CONCLUSIONS: The described case is followed by a discussion of cardiovascular involvement in systemic sclerosis and emphasizes that heart involvement in SSc may have very serious clinical implications. 相似文献
43.
44.
45.
J Krupińska J Mazur J Piotrowicz B Cebo R Stephanus 《Polish journal of pharmacology and pharmacy》1986,38(2):149-156
A series of amino acid derivatives of indometacin (IND) was investigated in regard to their protein binding and prostaglandin synthetase inhibition in vitro, and to acute toxicity, anti-inflammatory, antiedemic, analgesic actions, and the influence on the central nervous system in vivo. In biochemical tests the compounds were several times less potent than IND. They differed among themselves in the respect of toxicity, which was always much lower than that of IND. Out of eight compounds investigated N-IND-glycine (K1) and N-IND-epsilon-aminocaproic acid (K5) exerted more favorable antiedemic and analgesic action than IND did. Both the derivatives only weakly inhibited the cotton-pellet granuloma formation. K1 acted similarly to IND in the arthritis test. K1, K5 and IND similarly irritated the gastric mucosa. A modification of IND structure by introduction of glycine or epsilon-aminocaproic acid resulted in two new anti-inflammatory agents of more favorable therapeutic index in the antiedemic and analgesic action and of much lower toxicity than the reference compound. 相似文献
46.
47.
M Ochocka E Zelenay J Starzyńska E Chmarzyńska J Witkowska 《Acta haematologica Polonica》1991,22(2):233-241
Cytogenetic examinations were carried out in 40 children with acute leukaemia. In 18 cases karyotype changes were demonstrated, in 8 cases the karyotype was normal, in 14 cases no cell division was obtained and these patients were excluded from further analysis. In the group with karyotype changes in most cases poor prognosis indices were found, including high number of blasts, extramedullary presence of leukaemic infiltrations and FAB L2 or L3. Chromosomal abnormalities included presence of aberrations in the form of translocation, mosaicism of karyotypes with nearly tetraploidy line, accessory marker chromosomes and other anomalies. In this group 8 children died (30% of all observed cases), while in the group without karyotype changes 2 children died (about 8%). In summary the authors stress the correlation between the presence of clinical prognostic factors (risk factors) and karyotype changes and worse prognosis in cases with chromosomal abnormalities. Attention is called to the great usefulness of cytogenetic examinations in the prognosis and treatment of leukaemias in children. 相似文献
48.
In six young and two senile MS cases perivascular astrocytes within demyelination lesions were evaluated immunocytochemically. The peroxidase-antiperoxidase method of Sternberger et al. (1970) was used for visualization of glial fibrillary acidic protein (GFAP). In all cases very weak immunoreactivity of perivascular astrocytes was noted. Accumulation of perivascular glial fibers, and infrequently their fragmentation were observed both within active and old demyelination plaques. Clasmatodendrosis, Rosenthal's fibers and prominent regressive changes of astrocyte perikarya were found only in old plaques. A lack of immunoreactivity of perivascular astrocytes was noted within old demyelination lesions. The background of the latter was often immunonegative to GFAP. It is suggested that secondary damage of perivascular astrocytes influences vascular permeability within demyelination lesions including old plaques. 相似文献
49.
50.
W Kostowski E Malatyńska A P?a?nik W Dyr W Danysz 《Polish journal of pharmacology and pharmacy》1986,38(5-6):471-481
Alprazolam, a new benzodiazepine from triazolobenzodiazepine group, produced anxiolytic action in the conflict test with potency similar to that of diazepam. The myorelaxant activity of the drug was relatively weak. Unlike desipramine, alprazolam failed to reduce the immobility of rats in the forced swim test and was unable to prevent clonidine-induced hypothermia. Alprazolam, unlike desipramine, failed also to potentiate behavioral effect of noradrenaline injected into the hippocampus. Alprazolam after acute but not chronic administration antagonized the synchronizing effect of clonidine on EEG pattern. On the other hand, alprazolam similarly to tricyclic antidepressants, prevented the suppression of dominance behavior by clonidine in rats competing for food. The results indicate that alprazolam acts only weakly upon noradrenergic mechanisms related to depression and to antidepressant action of drugs. 相似文献