全文获取类型
收费全文 | 6910篇 |
免费 | 584篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 64篇 |
儿科学 | 238篇 |
妇产科学 | 131篇 |
基础医学 | 1009篇 |
口腔科学 | 140篇 |
临床医学 | 880篇 |
内科学 | 1409篇 |
皮肤病学 | 63篇 |
神经病学 | 600篇 |
特种医学 | 213篇 |
外科学 | 651篇 |
综合类 | 89篇 |
一般理论 | 4篇 |
预防医学 | 760篇 |
眼科学 | 263篇 |
药学 | 453篇 |
1篇 | |
中国医学 | 2篇 |
肿瘤学 | 531篇 |
出版年
2022年 | 54篇 |
2021年 | 90篇 |
2020年 | 58篇 |
2019年 | 91篇 |
2018年 | 105篇 |
2017年 | 71篇 |
2016年 | 103篇 |
2015年 | 135篇 |
2014年 | 169篇 |
2013年 | 226篇 |
2012年 | 275篇 |
2011年 | 336篇 |
2010年 | 195篇 |
2009年 | 150篇 |
2008年 | 256篇 |
2007年 | 308篇 |
2006年 | 319篇 |
2005年 | 288篇 |
2004年 | 275篇 |
2003年 | 219篇 |
2002年 | 256篇 |
2001年 | 231篇 |
2000年 | 232篇 |
1999年 | 171篇 |
1998年 | 90篇 |
1997年 | 76篇 |
1996年 | 81篇 |
1995年 | 76篇 |
1994年 | 73篇 |
1993年 | 62篇 |
1992年 | 160篇 |
1991年 | 183篇 |
1990年 | 153篇 |
1989年 | 183篇 |
1988年 | 145篇 |
1987年 | 156篇 |
1986年 | 165篇 |
1985年 | 144篇 |
1984年 | 113篇 |
1983年 | 85篇 |
1982年 | 52篇 |
1981年 | 59篇 |
1980年 | 68篇 |
1979年 | 97篇 |
1978年 | 60篇 |
1977年 | 60篇 |
1975年 | 51篇 |
1974年 | 53篇 |
1973年 | 56篇 |
1971年 | 53篇 |
排序方式: 共有7501条查询结果,搜索用时 15 毫秒
991.
J M Hurff M K Poulsen J Van Hoven S Olson 《The American journal of occupational therapy》1985,39(4):233-239
During the past decade, there has been a thrust, both socially and legally, to integrate adults with developmental disabilities, particularly those with mental retardation, into community life. Libraries, which are resources in the community for all citizens, can play a significant role in this integration. This article describes the format and outcome of a California-based library program for mentally retarded adults. It describes the materials developed, gives the contributions made by an interdisciplinary team, and discusses occupational therapy's role in the implementation of this community program. 相似文献
992.
993.
A new catheter system was used in ten patients (16 infusions) for infusion of chemotherapeutic agents to the sites of malignant gliomas. Thirteen infusions to the supraophthalmic region were successful, as were three infusions to the posterior cerebral region. There were no complications after the infusions. A neurologic complication occurred in one patient in whom two successful supraophthalmic infusions were previously carried out. In this patient the guide wire separated during catheter placement into the posterior cerebral artery. 相似文献
994.
995.
996.
997.
O Amédée-Manesme H C Furr F Alvarez M Hadchouel D Alagille J A Olson 《Hepatology (Baltimore, Md.)》1985,5(6):1143-1148
Biochemical indicators of vitamin A status were measured in 24 children (1 month to 6 years old) with severe cholestasis starting early in life and in 21 children (3 months to 13 years old) with liver disease but without cholestasis. Liver vitamin A concentrations, expressed as micrograms of retinol per gram of liver (mean +/- S.D.), were 6.3 +/- 7.1 (range: 0.14 to 28) and 143 +/- 108 (range: 18 to 424), respectively, in cholestatic and non-cholestatic children. In infants less than 6 months of age, liver vitamin A values less than 10 micrograms per gm were found in 14 of 17 cholestatic children but in none of 3 non-cholestatic subjects. Plasma vitamin A values, expressed as micrograms of retinol per deciliter (mean +/- S.D.), were 23 +/- 18 (range: 3 to 62) and 46 +/- 33 (range: 14 to 125), respectively, for the two groups. Plasma retinol values less than 10 micrograms per dl were always associated with liver concentrations less than 10 micrograms per gm. Plasma retinol-binding protein was only reduced to 71% of control values in cholestatic children. The fatty acid composition of liver retinyl esters was unaffected by any condition studied. Infants with chronic cholestasis are in a precarious nutritional status very early in life relative to liver reserves of vitamin A. Plasma vitamin A values, unless less than 10 micrograms retinol per dl, are poor indicators of inadequate vitamin A status. 相似文献
998.
James D Guest Arundathi Rao Les Olson Mary Bartlett Bunge Richard P Bunge 《Experimental neurology》1997,148(2):502-522
Advances in the purification and expansion of Schwann cells (SCs) from adult human peripheral nerve, together with biomaterials development, have made the construction of unique grafts with defined properties possible. We have utilized PAN/PVC guidance channels to form solid human SC grafts which can be transplanted either with or without the channel. We studied the ability of grafts placed with and without channels to support regeneration and to influence functional recovery; characteristics of the graft and host/graft interface were also compared. The T9–T10 spinal cord of nude rats was resected and a graft was placed across the gap; methylprednisolone was delivered acutely to decrease secondary injury. Channels minimized the immigration of connective tissue into grafts but contributed to some necrotic tissue loss, especially in the distal spinal cord. Grafts without channels contained more myelinated axons (x= 2129 ± 785) vs (x = 1442 ± 514) and were larger in cross-sectional area (x = 1.53 ± 0.24 mm2) vs (x= 0.95 ± 0.86 mm2). The interfaces formed between the host spinal cord and the grafts placed without channels were highly interdigitated and resembled CNS–PNS transition zones; chondroitin sulfate proteoglycans was deposited there. Whereas several neuronal populations including propriospinal, sensory, motoneuronal, and brainstem neurons regenerated into human SC grafts, only propriospinal and sensory neurons were observed to reenter the host spinal cord. Using combinations of anterograde and retrograde tracers, we observed regeneration of propriospinal neurons up to 2.6 mm beyond grafts. We estimate that 1% of the fibers that enter grafts reenter the host spinal cord by 45 days after grafting. Following retrograde tracing from the distal spinal cord, more labeled neurons were unexpectedly found in the region of the dextran amine anterograde tracer injection site where a marked inflammatory reaction had occurred. Animals with bridging grafts obtained modestly higher scores during open field [(x = 8.2 ± 0.35) vs (x = 6.8 ± 0.42),P = 0.02] and inclined plane testing (x = 38.6 ± 0.542) vs (x= 36.3 ± 0.53),P = 0.006] than animals with similar grafts in distally capped channels. In summary, this study showed that in the nude rat given methylprednisolone in combination with human SC grafts, some regenerative growth occurred beyond the graft and a modest improvement in function was observed. 相似文献
999.
A 17-month-old Thai female with neuroblastoma presented with an abdominal mass and the classical findings of kwashiorkor. Concomitant with effective repair of the child's protein deficit, the mass enlarged dramatically and metastases were noted. This is the first known report of such an occurrence. 相似文献
1000.
L Fuller V Esquenazi M Carreno R Alejandro V Pardo D Roth D Schultz L Olson M Milgrom J Miller 《Transplantation》1988,45(3):591-600
Two murine anticanine lymphocyte monoclonal antibodies, designated T83 and B1F6, were assessed for (1) in vitro antiepitope activity to circulating lymphocyte subsets, their functional effects on lymphoproliferative assays and binding specificities to diverse cell suspensions and tissue sections; (2) in vivo effects after administration on cells expressing the target epitopes, lymphoproliferation, and allograft survival; and (3) the host immune response to the injected murine immunoglobulins. The monoclonal antibody T83 (IgG3) appeared to be specific for a T cell subset with an up-regulating function on lymphoproliferation. It caused a profound depletion of cells with the appropriate epitope after intravenous administration but it bound to lymphocyte membrane epitopes on some cells in peripheral blood that did not become depleted and putatively caused other modulating effects on lymphocyte function. The monoclonal antibody B1F6 (IgG2a, previously described) was immunologically specific in vitro for cells expressing class II major histocompatibility complex antigens. In the dog, this also consisted of 50% of T lymphocytes. After intravenous administration, there were functional effects similar to those of T83. A modest prolongation of survival of renal allografts was observed when both mAbs were used as the sole immunosuppressive agent. These studies also demonstrated the occurrence of natural canine antimurine IgG antibodies. Administration of either monoclonal antibody was followed by a rapid increase in the concentration of the antimouse antibody(s). We postulate that the presence of canine natural antimouse IgG markedly influenced the biologic effects of in vivo administered monoclonals. 相似文献