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991.
Mogens Dam 《Acta neurologica Scandinavica》1998,97(3):145-145
992.
Pia Kjær Kristensen Mogens Pfeiffer-Jensen Jens Ole Storm Theis Muncholm Thillemann 《Knee surgery, sports traumatology, arthroscopy》2014,22(2):317-323
Purpose
Arthroscopic anterior cruciate ligament (ACL) reconstruction is a painful procedure requiring intensive postoperative pain management. Femoral nerve block is widely used in ACL surgery. However, femoral nerve block does not cover the donor site of the hamstring tendons. Local infiltration analgesia is a simple technique that has proven effective in postoperative pain management after total knee arthroplasty. Further, local infiltration analgesia covers the donor site and is associated with few complications. It was hypothesised that local infiltration analgesia at the donor site and wounds would decrease pain and opioid consumption after ACL reconstruction with hamstring tendon graft.Methods
Sixty patients undergoing primary ACL surgery with hamstring tendon graft were randomised to receive either local infiltration analgesia or femoral nerve block. Pain was scored on the numeric rating scale, and use of opioid, range of motion and adverse effects were assessed at the postoperative recovery unit (0 h), 3, 24 and 48 h, postoperatively.Results
There were no significant differences between the groups in pain intensity or total opioid consumption at any of the follow-up points. Further, there were no differences between groups concerning side effects and range of motion.Conclusions
Local infiltration analgesia and femoral nerve block are similar in the management of postoperative pain after ACL reconstruction with hamstring tendon graft. Until randomised studies have investigated femoral nerve block combined with infiltration at the donor site, we recommend local infiltration analgesia in ACL reconstruction with hamstring tendon graft.Level of evidence
I. 相似文献994.
995.
996.
Alfred A. Bove 《The Physician and sportsmedicine》2013,41(3):36-40
AbstractThe understanding of tendinopathy has evolved over the past several decades. Initially thought to be a primarily inflammatory process, histologic evaluation has revealed that there is an absence of inflammatory cells, and rather, tendinopathy is more of a degenerative process. Various types of medications, rehabilitation, modalities, injections, and minimally invasive procedures have been described as treatment for this condition. The purpose of our article is to describe the pathophysiology of tendinopathy as currently understood and the evidence for the various available treatments. We performed a literature search to determine the types of reviews that have been performed previously regarding treatment for tendinopathy, and summarized these reviews. We then performed a systematic review of randomized controlled trials for treating patients with tendinopathy. It is our hope that our review of trial data will help providers to determine optimal management for their patients with tendinopathy. 相似文献
997.
Johs. Glavind Lis Hansen Mogens Faber 《International journal of radiation biology》2013,89(5):409-420
SummaryAntioxidants in organs of normal and irradiated rats were determined by means of the stable free-radical α,α-diphenyl-β-picrylhydrazyl. High doses of ionizing radiation reduced the level of water-soluble antioxidants; the fat-soluble antioxidants were unaffected, and the ability of the proteins to react with the stable free radical was unchanged or slightly elevated. It is concluded that the water-soluble non-protein antioxidants act as free radical scavengers in radiation. No great amounts of lipoperoxides were found in the irradiated animals. The basic analogy, but at the same time the great dissimilarities, between free radical processes in radiation and in autoxidation is discussed. 相似文献
998.
Pernille Lind Ulrik Hintze Mogens Møller Hans Mickley 《Scandinavian cardiovascular journal : SCJ》2013,47(2):92-95
Objective - The purpose of this study was to evaluate the effects of thrombolytic therapy on vagal tone after acute myocardial infarction (AMI). Design - Holter monitoring for 24 h was performed at hospital discharge and 6 weeks after AMI in 74 consecutive male survivors of a first AMI, who fulfilled established criteria for thrombolytic therapy. Thirty-five patients received thrombolyses, while the remaining 39 patients did not (controls). In each Holter recording 24-h heart rate variability was calculated as pNN50, which represents the percentage of successive RR interval differences >50 ms. Alterations in pNN50 are known to reflect changes in vagal tone. Results - The analysis showed that controls early after AMI had low pNN50 values without any diurnal changes. Six weeks after AMI pNN50 values in controls exhibited a circadian rhythm with higher values during night-time. This pattern was similar to the pattern observed in thrombolysed patients early after AMI. In thrombolysed patients pNN50 values, particularly at night, were further improved 6 weeks after AMI (p = 0.037). Conclusion - These observations indicate that thrombolytic therapy, given for a first AMI, preserves vagal activity when compared with patients who are not thrombolysed. The enhanced parasympathetic tone may be a part of the beneficial mechanisms responsible for the reduction in mortality after thrombolysis in AMI. 相似文献
999.
1000.