全文获取类型
收费全文 | 23364篇 |
免费 | 1247篇 |
国内免费 | 50篇 |
专业分类
耳鼻咽喉 | 368篇 |
儿科学 | 508篇 |
妇产科学 | 548篇 |
基础医学 | 3312篇 |
口腔科学 | 2219篇 |
临床医学 | 1469篇 |
内科学 | 4724篇 |
皮肤病学 | 454篇 |
神经病学 | 2122篇 |
特种医学 | 620篇 |
外科学 | 2586篇 |
综合类 | 55篇 |
一般理论 | 8篇 |
预防医学 | 2435篇 |
眼科学 | 540篇 |
药学 | 1850篇 |
中国医学 | 206篇 |
肿瘤学 | 637篇 |
出版年
2023年 | 218篇 |
2022年 | 338篇 |
2021年 | 693篇 |
2020年 | 440篇 |
2019年 | 663篇 |
2018年 | 1042篇 |
2017年 | 734篇 |
2016年 | 716篇 |
2015年 | 720篇 |
2014年 | 866篇 |
2013年 | 1218篇 |
2012年 | 2012篇 |
2011年 | 2314篇 |
2010年 | 1063篇 |
2009年 | 722篇 |
2008年 | 1585篇 |
2007年 | 1573篇 |
2006年 | 1321篇 |
2005年 | 1286篇 |
2004年 | 1194篇 |
2003年 | 971篇 |
2002年 | 711篇 |
2001年 | 355篇 |
2000年 | 372篇 |
1999年 | 267篇 |
1998年 | 87篇 |
1997年 | 44篇 |
1996年 | 52篇 |
1995年 | 43篇 |
1994年 | 38篇 |
1993年 | 33篇 |
1992年 | 64篇 |
1991年 | 76篇 |
1990年 | 56篇 |
1989年 | 48篇 |
1988年 | 50篇 |
1987年 | 39篇 |
1986年 | 49篇 |
1985年 | 74篇 |
1984年 | 42篇 |
1983年 | 25篇 |
1981年 | 26篇 |
1980年 | 25篇 |
1978年 | 39篇 |
1975年 | 23篇 |
1974年 | 27篇 |
1971年 | 33篇 |
1970年 | 29篇 |
1969年 | 29篇 |
1968年 | 21篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
Barreto DF Takiya CM Paes MV Farias-Filho J Pinhão AT Alves AM Costa SM Barth OM 《Journal of submicroscopic cytology and pathology》2004,36(2):121-130
The difficulty in studying dengue virus (DENV) infection in humans and in developing a virus vaccine is the absence of a suitable animal model which develops the full spectra of the Dengue haemorrhagic fever (DHF) and Dengue shock syndrome (DSS). Despite the fact that viruses have been found in various animal tissues, we isolated DENV from tissues of adult BALB/c mice, inoculated with DENV serotype 2 (DENV-2) obtained from human serum. Viruses were ultrastructurally identified and immunolocalized by immunofluorescence techniques in C6/36 mosquito cell cultures, inoculated with tissues (liver, lung, kidney and cerebellum) macerate supernatant from mice, 48 h post-infection (p.i.). These organs, collected at the same stage of infection, were examined histologically. The histopathological analysis revealed focal alterations in all tissues examined. Liver contained focal ballooned hepatocytes, but without modifying the average diameter of the majority of hepatocytes. Sinusoidal lumen was significantly diminished at this stage but portal and centrolobular veins became congested. Lungs exhibited hemorrhagic foci in the alveolar space, vascular congestion and focal alveolitis. Cerebellar tissue showed rare foci of neuronal compactation (Purkinje cells) and perivascular oedema. In kidneys it was observed an increase in glomerular volume with augmented endocapillary and mesangial cellularity, with reactivity to anti-IgM in all glomeruli of infected mice. In conclusion, DENV-2 was found in all tissues examined early in the evolution of infection. Presence of viruses in tissues has mainly led to hemodynamic alterations with generalized vascular congestion and increased permeability, and mast cell recruitment in lungs. The latter could participate in the vascular modifications in tissues. 相似文献
72.
Summary. The genome structure of six bacteriophages of Oenococcus oeni was compared. Two distinct groups with no apparent restriction site conservation were defined. In members of the α group
(fOgML34, fOg4029, fOg30 and fOg218) a 7.5 kb region containing the origin of DNA packaging (cos) was highly conserved. Stretches of DNA heterogeneity could also be assigned to particular regions and were mostly evident
in the right area of the genomes. fOg44 and fOgPSU1 (β group) were indistinguishable in the left half of their genomes, including
cos, but were markedly dissimilar in other regions. Strong labelling signals detected in cross-hybridizations involving members
of different groups were confined to fragments centrally located in their physical maps. The attachment site (attP) of fOg44 was assigned to this conserved region. It is suggested that recombination events at this location may have been
important in generating the observed diversity of oenophage genomes.
Accepted October 15, 1997 Received August 11, 1997 相似文献
73.
In order to assess the role played by serotonin (5-HT) and noradrenaline in anxiety, four groups of healthy volunteers were given 25 mg of the selective inhibitor of 5-HT uptake chlorimipramine, 50 mg of the selective inhibitor of noradrenaline uptake maprotiline, 1 mg of the benzodiazepine anxiolytic lorazepam or placebo, and submitted to a simulated public speaking (SPS) test, consisting of speaking in front of a videocamera. Subjective anxiety was evaluated by the visual analog mood scale (VAMS) of Norris as well as by the state-trait anxiety inventory (STAI) of Spielberger. Chlorimipramine enhanced SPS-induced anxiety, whereas maprotiline and lorazepam reduced anxiety during as well as outside the test period. Mental and physical sedation (VAMS) were increased by either maprotiline or lorazepam. In a scale of bodily symptoms, chlorimipramine tended to increase muscle tension, agitation and palpitation, whereas maprotiline caused lethargy. The rise in blood pressure induced by the SPS procedure outlasted the period of stress in the group treated with chlorimipramine. In contrast, the SPS-induced increase in heart rate was enhanced by lorazepam. Chlor imipramine and maprotiline reduced salivation to the same extent. Pupillary diameter, however, was significantly increased by chlorimipramine alone. It may be tentatively sug gested that the proanxiogenic effect of chlorimipramine is related to changes in central 5-HT neurotransmission while the anxiolytic effect of maprotiline is associated with alteration of noradrenergic mechanisms. Increased peripheral sympathetic tone may also contribute to the proanxiety action of chlorimipramine. 相似文献
74.
Lopes Amanda Forster Machado Thais Costa Nascimento Viviane Gabriela Bertoli Ciro João Leone Claudio 《Maternal and child health journal》2022,26(6):1305-1311
Maternal and Child Health Journal - To study the relationship between cesarean Delivery (CD) and overweight in preschool children, considering the presence of birth aspects and demographic... 相似文献
75.
Nascimento Bruno Andrade Hiury S. Miranda Eduardo P. Barbosa João Arthur Brunhara Alves Moscardi Paulo R. Arap Marco A. Mitre Anuar I. Srougi Miguel Srougi Victor Duarte Ricardo J. 《International urology and nephrology》2021,53(2):269-273
International Urology and Nephrology - To evaluate outcomes of laparoscopic pyeloplasty (LP) in adults with poorly functioning kidney due to ureteropelvic junction obstruction (UPJO). A... 相似文献
76.
Neves Lia Mara Grosso Tim Carla Roberta Floriano Elaine Medeiros da Silva de Avó Lucimar Retto Fernandes João Batista Parizotto Nivaldo Antonio Cominetti Marcia Regina 《Lasers in medical science》2021,36(4):863-870
Lasers in Medical Science - Ultraviolet radiation (UVR) is the major etiologic agent of cutaneous photoaging, and different strategies are used to prevent and treat this condition. The... 相似文献
77.
Amadio Eliane Martins Marcos Rodrigo Labat Serra Andrey Jorge dos Santos Solange Almeida Caires Jheniphe Rocha Fernandes Guilherme Henrique Cardosos Leal-Junior Ernesto Cesar Ferrari João Carlos Correa de Tarso Camillo de Carvalho Paulo 《Lasers in medical science》2021,36(7):1427-1435
Lasers in Medical Science - Photobiomodulation therapy (PBMT) has been indicated for enforcement on healing skin wounds. This study evaluated the effects of PBMT on the healing of skin wounds... 相似文献
78.
Vassão Patricia Gabielli Parisi Julia Penha Thaíse Fernanda Campos Balão Ana Beatriz Renno Ana Claudia Muniz Avila Mariana Arias 《Lasers in medical science》2021,36(7):1341-1353
Lasers in Medical Science - Knee osteoarthritis (KOA) is a common degenerative disease in which several treatments and treatment associations have been investigated. This review analyzed the... 相似文献
79.
Costa Davidson Ribeiro Pessoa Diego Rodrigues Seefeldt Vanessa Borelli Costa David Ribeiro Maia Daniel Tineu Leite dos Santos Maciel Thiago Mota Brenda Barros Magalhães Delpasso Carolina Alves Ribeiro Camila Alves Delpasso Nicolau Renata Amadei 《Lasers in medical science》2021,36(8):1681-1689
Lasers in Medical Science - This study compared the effects of LED therapy associated with occlusal splint (OS) on the signs and symptoms of temporomandibular disorder (TMD). In this randomized,... 相似文献
80.
Stamborowski Sadi Fernando de Oliveira Spinelli Bruna Moreira Lima Fernanda Pupio Silva Costa Davidson Ribeiro de Silveira Souza Gabriela Aparecida Lima Mario Oliveira Lopes Martins Rodrigo Alvaro Brandão 《Lasers in medical science》2021,36(8):1741-1749
Lasers in Medical Science - Physical activity raises body temperature. However, the literature does not contain studies about whether the employment of hotobiomodulation (PMB) could significantly... 相似文献