全文获取类型
收费全文 | 41743篇 |
免费 | 1958篇 |
国内免费 | 182篇 |
专业分类
耳鼻咽喉 | 617篇 |
儿科学 | 816篇 |
妇产科学 | 457篇 |
基础医学 | 5134篇 |
口腔科学 | 1298篇 |
临床医学 | 2917篇 |
内科学 | 9512篇 |
皮肤病学 | 866篇 |
神经病学 | 3838篇 |
特种医学 | 1977篇 |
外国民族医学 | 1篇 |
外科学 | 6658篇 |
综合类 | 156篇 |
一般理论 | 6篇 |
预防医学 | 1316篇 |
眼科学 | 830篇 |
药学 | 2729篇 |
中国医学 | 94篇 |
肿瘤学 | 4661篇 |
出版年
2023年 | 226篇 |
2022年 | 409篇 |
2021年 | 749篇 |
2020年 | 422篇 |
2019年 | 547篇 |
2018年 | 688篇 |
2017年 | 595篇 |
2016年 | 777篇 |
2015年 | 709篇 |
2014年 | 933篇 |
2013年 | 1174篇 |
2012年 | 1917篇 |
2011年 | 2016篇 |
2010年 | 1238篇 |
2009年 | 1056篇 |
2008年 | 1806篇 |
2007年 | 2089篇 |
2006年 | 2011篇 |
2005年 | 1997篇 |
2004年 | 1982篇 |
2003年 | 1794篇 |
2002年 | 1826篇 |
2001年 | 1361篇 |
2000年 | 1483篇 |
1999年 | 1340篇 |
1998年 | 579篇 |
1997年 | 487篇 |
1996年 | 428篇 |
1995年 | 358篇 |
1994年 | 360篇 |
1993年 | 319篇 |
1992年 | 1015篇 |
1991年 | 885篇 |
1990年 | 829篇 |
1989年 | 823篇 |
1988年 | 780篇 |
1987年 | 781篇 |
1986年 | 679篇 |
1985年 | 641篇 |
1984年 | 431篇 |
1983年 | 356篇 |
1979年 | 306篇 |
1978年 | 212篇 |
1977年 | 190篇 |
1974年 | 193篇 |
1973年 | 163篇 |
1972年 | 161篇 |
1971年 | 181篇 |
1970年 | 155篇 |
1969年 | 179篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
42.
43.
N Sadatoh H Hatabu M Takahashi K Imanaka A Sano 《Journal of computer assisted tomography》1987,11(4):742-744
To achieve prolonged breath-holding, oxygen was administered just before dynamic CT and high resolution lung CT. Oxygen administration has proved to be a supportive means to improve the quality of CT studies. 相似文献
44.
45.
Shinichi Toyooka Hideaki Mori Katsuyuki Kiura Hiroshi Date 《European journal of cardio-thoracic surgery》2008,33(2):315-316
We present a case of a 58-year-old man with diagnosis of lung adenocarcinoma invading the left atrium. He was treated with induction chemoradiotherapy for T4N1M0 disease, showing objective response. Then, a left upper lobectomy with a partial resection of the left atrium was performed without cardiopulmonary bypass. No residual tumor cells existed in the resected specimens, showing pathological complete response. Our case suggests that induction chemoradiotherapy prior to surgery can be an appropriate strategy among carefully selected patients with non-small cell lung cancer invading the left atrium. 相似文献
46.
Naoko Masuzawa Mitsuo Kishimoto Yoshiki Takahashi 《International journal of gynecological pathology》2003,22(3):285-288
A 57-year-old female presented with an abnormal Pap smear. Colposcopic examination of the cervix revealed white mucosa with erosion and several areas of black pigmentation. After a colposcopically directed biopsy and loop conization, radical hysterectomy and bilateral salpingo-oophorectomy with pelvic and paraaortic lymphadenectomy were performed. Pathological examination disclosed an invasive squamous cell carcinoma admixed with many dendritic melanocytes. Melanin granules were present within the melanocytes and tumor cells. Although similar tumors have been reported in other sites, this is the first report to our knowledge of a pigmented squamous cell carcinoma of the uterine cervix. 相似文献
47.
Naoya Katsuragi Yutsuki Nakajima Yuji Shiraishi Masahiro Hashizume Nobumasa Takahashi 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2005,53(8):440-442
We describe a case of a large bronchial fistula and empyema after right upper lobectomy that was treated successfully with
open window thoracostomy followed by a latissimus dorsi myocutaneous flap and limited thoracoplasty. A latissimus dorsi myocutaneous
flap can provide immediate airtight closure of a large bronchial fistula, allowing lavage and curettage of the empyema cavity
to reduce the chance of postoperative infection. An important aspect of this technique is that the deepithelialized skin side
rather than muscle is sutured to an opening of the bronchus. As compared with other techniques, a latissimus dorsi myocutaneous
flap is superior in that it requires a single incision and does not require an intraop-erative change of position. In addition,
the technique causes little dysfunction of the chest and shoulder and preserves the vascular supply to ensure the viability
of the flap even if it was divided in a previous operation. 相似文献
48.
49.
p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. 总被引:20,自引:0,他引:20
H Suzuki T Takahashi T Kuroishi M Suyama Y Ariyoshi T Takahashi R Ueda 《Cancer research》1992,52(3):734-736
The p53 gene has been implicated as a tumor suppressor gene involved in the pathogenesis of lung cancer. Our previous study revealed that the p53 gene is frequently mutated with a distinct nucleotide substitution pattern in small cell lung cancer specimens in Japanese patients. In this study, we examined 30 primary, resected non-small cell lung cancer samples in Japanese patients using complementary DNA-polymerase chain reaction and sequencing. Mutations changing the p53 coding sequence were found in 14 of 30 tumor samples (47%), while G:C to T:A transversions which are uncommon in other cancers such as colon cancer were the most frequently observed mutations, in agreement with an earlier report on non-small cell lung cancer in American patients. Furthermore, the present study shows for the first time that in univariate and multivariate analyses, the presence of p53 mutations is closely associated with lifetime cigarette consumption. 相似文献
50.
A Nishikawa F Furukawa M Mitsui T Enami T Kawanishi T Hasegawa M Takahashi 《Carcinogenesis》1992,13(7):1155-1158
The effects of calcium chloride on glandular stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and sodium chloride were investigated in male outbred Wistar rats. Animals were given MNNG solution (100 p.p.m.) as drinking water and simultaneously fed a diet supplemented with 5% sodium chloride for 8 weeks. Matched negative controls received neither MNNG nor sodium chloride. Rats were then fed basal diet and given calcium chloride solution (1 or 0.2%) or tap water for the following 52 weeks. The incidences and multiplicities of preneoplastic hyperplasias in the glandular stomachs of rats given MNNG/sodium chloride followed by 1 and 0.2% calcium chloride were significantly lower than those in rats given MNNG/sodium chloride alone. The inhibitory effects of calcium were exerted in a dose-dependent manner. Calcium treatment also showed a tendency to inhibit the development of gastric adenocarcinomas although this was not statistically significant. Rats without carcinogen treatment had neither carcinomas nor preneoplastic hyperplasias in the glandular stomach. Calcium intake also significantly reduced the levels of malondialdehyde, a measure of lipid peroxidation, in the gastric mucosa and urine, the former in a dose-dependent manner. Thus, calcium chloride exerted inhibitory effects when given during the post-initiation phase of two-stage glandular stomach carcinogenesis in rats. 相似文献