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781.
782.
783.
BM McDermott AA Mamun JM Najman GM Williams MJ O'Callaghan W Bor 《Acta paediatrica (Oslo, Norway : 1992)》2010,99(1):68-71
Aim: To report the stability of parent-perceived child irregular eating from 6 months to 14 years of age and to investigate a predictive model inclusive of child and parent factors.
Methods: Of the 7223 singleton children in a birth cohort, 5122 children were re-interviewed at 5 years and 4554 for the 14-year analysis. Information was obtained from structured interviews including questions answered by parents of the child at birth, 6 months, 5 years and 14 years; and by teenagers at age 14 years and from physical measures of the child. The mother's perception that the child was an irregular eater at age 14 years was the major outcome variable of interest.
Results: Approximately 40% of irregular eaters at age 5 will still be irregular eaters at age 14 years. This was not related to maternal education or socio-economic class. Significant at multivariate analysis were infant feeding problems and the children's ability to regulate their sleep and mood. Significant maternal factors were greater age, not feeling positive about the baby and persistent maternal anxiety during the child's early years.
Conclusion: Irregular eating behaviour displays considerable continuity from childhood to mid-adolescence. Independent contributions to this behavioural phenotype include child biological and psychological factors and maternal anxiety during the child's early years. 相似文献
Methods: Of the 7223 singleton children in a birth cohort, 5122 children were re-interviewed at 5 years and 4554 for the 14-year analysis. Information was obtained from structured interviews including questions answered by parents of the child at birth, 6 months, 5 years and 14 years; and by teenagers at age 14 years and from physical measures of the child. The mother's perception that the child was an irregular eater at age 14 years was the major outcome variable of interest.
Results: Approximately 40% of irregular eaters at age 5 will still be irregular eaters at age 14 years. This was not related to maternal education or socio-economic class. Significant at multivariate analysis were infant feeding problems and the children's ability to regulate their sleep and mood. Significant maternal factors were greater age, not feeling positive about the baby and persistent maternal anxiety during the child's early years.
Conclusion: Irregular eating behaviour displays considerable continuity from childhood to mid-adolescence. Independent contributions to this behavioural phenotype include child biological and psychological factors and maternal anxiety during the child's early years. 相似文献
784.
Bram Perdu Fenna de Freitas Suzanne GM Frints Meyke Schouten Connie Schrander‐Stumpel Mafalda Barbosa Jorge Pinto‐Basto Margarida Reis‐Lima Marie‐Christine de Vernejoul Kristin Becker Marie‐Louise Freckmann Kathlijn Keymolen Eric Haan Ravi Savarirayan Rainer Koenig Bernhard Zabel Filip M Vanhoenacker Wim Van Hul 《Journal of bone and mineral research》2010,25(1):82-90
785.
Dell'Aquila ME; Cho YS; Minoia P; Traina V; Lacalandra GM; Maritato F 《Human reproduction (Oxford, England)》1997,12(12):2766-2772
The aim of this study was to compare the effect of the addition of
follicular fluid (FF) collected from preovulatory follicles with that of
oestrous mare serum (EMS) (acting as the control) to TCM-199 medium on the
in-vitro maturation, fertilization and development of equine
cumulus-enclosed oocytes. Oocytes (<30 mm in diameter) were obtained
from the ovaries of slaughtered mares. After in-vitro maturation in the
presence of the two supplements, their fertilization, cleavage and
developmental potential were compared after conventional in-vitro
fertilization (IVF) or intracytoplasmic sperm injection (ICSI) using
frozen-thawed spermatozoa. Follicular fluid did not increase the maturation
of oocytes to metaphase II stage compared to control. After IVF, there was
no difference in fertilization rates between FF- supplemented oocytes and
controls (7/87, 8.4% of oocytes showing two pronuclei with FF versus 7/116,
6% with EMS; not significant). However, after ICSI, FF-supplemented oocytes
showed significantly increased normal fertilization (32/85, 37.6% of
two-pronuclear oocytes) and developmental potential (15/31, 48% cleavage)
compared to the control oocytes (7/47, 14.9%, P < 0.01; and 2/48, 4%, P
< 0.01, respectively). Overall, ICSI resulted in increased fertilization
rates compared to IVF, regardless of the presence or absence of FF (39/132,
29.5% with ICSI versus 14/203, 6.9%). These results suggest that follicular
fluid supplementation may improve the maturity of equine cumulus-enclosed
oocytes sufficiently for the successful use of ICSI, but not sufficiently
for normal sperm-egg interaction occurring during IVF.
相似文献
786.
We studied the diagnostic predictive power of transrectal ultrasonography
(TRUS) coupled with semen volume in cases of distal seminal tract
sub-obstruction. As a gold standard for diagnosis we used seminal tract
washout (STW). Non-azoospermic subjects (n = 112) were submitted to
transrectal ultrasonography because of suspected excretory infertility or
other andrological pathologies, before performing STW. STW indicated
ejaculatory duct sub-obstruction in 36.6% of the patients. Seminal vesicle
enlargement (anterior-posterior diameter > or = 15 mm) and seminal
vesicle roundish anechoic areas (stasis) were the ultrasonographic
anomalies more often associated with ejaculatory duct sub-obstruction.
Stepwise logistic regression (SLR) analysis revealed that the
ultrasonographic evidence of stasis was highly diagnostic only in the
presence of a low semen volume (< or = 1.5 ml) and that ejaculatory duct
sub-obstructions may be present but with no evidence of ultrasonographic
anomalies. Therefore, TRUS is a useful approach for the treatment of
suspected ejaculatory duct sub-obstruction, but is not a reliable
diagnostic tool and, before performing transurethral surgery, STW should be
mandatory.
相似文献
787.
788.
Shaun R. D. Watson Agatha E. Brizuela I. S. Curthoys James G. Colebatch Hamish G. MacDougall G. Michael Halmagyi 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1998,122(4):453-458
This study was designed to measure ocular movements evoked by galvanic (DC) stimulation using computerised video-oculography.
Long duration (>30 s) galvanic vestibular stimulation at currents of up to 5 mA through large-area surface electrodes over
the mastoid processes causes maintained changes in the ocular torsional position of both eyes in healthy human subjects. With
the subject seated and the head held firmly, torsion was measured by a computer-based image-processing system (VTM). Torsion
was recorded in darkness, with or without a single fixation point. With bilateral stimulation, the upper poles of both eyes
always torted away from the side of cathode placement and toward the anode. For unilateral stimulation, torsion was directed
away from the cathode or toward the anode. The magnitude of ocular torsion was dependent on current strength: with bilateral
stimulation the peak torsion was on average 2.88° for 5-mA current intensity compared with 1.58° for 3 mA. A smaller amplitude
of torsion was obtained for unilateral stimulation. The average peak torsion was the same for both eyes for all forms of stimulation.
Our findings indicate that low-intensity galvanic stimulation evokes ocular torsion in normal subjects, an effect which is
consistent with an action on otolith afferents.
Received: 27 March 1998 / Accepted: 23 June 1998 相似文献
789.
Anna Tylki-Szymaska Barbara Czartoryska Susanna Bunge Otto P van Diggelen Wim J Kleijer Ben JHM Poor-trims Jan GM Huijmans Danuta Górska 《Clinical genetics》1998,53(5):369-374
Mucopolysaccharidosis type IVA (Morquio A) is caused by a deficiency of N -acetylgalactosamine-6-sulfatase (GALNS), an enzyme capable of cleaving the sulfate group from both N -acetylgalactosamine-6-sulfate and galactose-6-sulfate. We describe here a two-generation Morquio A family with two distinct clinical phenotypes. The two probands from the second generation showed intermediate signs of the disease whereas their affected mother, aunt and two uncles had only very mild symptoms. Galactose-6-sulfatase (GALS) activity in leukocytes and fibroblasts of the affected family members was clearly deficient. Molecular genetic analysis of the GALNS gene revealed that two different point mutations segregate in the family, which correlated well with the clinical phenotype. The probands with intermediate symptoms were compound heterozygotes for the mutations R259Q and R94G, the latter one being inherited from the unaffected father. The mother and her affected siblings with the unusually mild phenotype were proven to be homozygous for the novel missense point mutation R259Q. 相似文献