全文获取类型
收费全文 | 1685篇 |
免费 | 287篇 |
国内免费 | 39篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 101篇 |
妇产科学 | 19篇 |
基础医学 | 90篇 |
口腔科学 | 26篇 |
临床医学 | 281篇 |
内科学 | 576篇 |
皮肤病学 | 60篇 |
神经病学 | 171篇 |
特种医学 | 279篇 |
外科学 | 185篇 |
综合类 | 31篇 |
预防医学 | 55篇 |
眼科学 | 16篇 |
药学 | 53篇 |
中国医学 | 1篇 |
肿瘤学 | 53篇 |
出版年
2024年 | 9篇 |
2023年 | 52篇 |
2022年 | 13篇 |
2021年 | 27篇 |
2020年 | 90篇 |
2019年 | 12篇 |
2018年 | 88篇 |
2017年 | 69篇 |
2016年 | 68篇 |
2015年 | 60篇 |
2014年 | 94篇 |
2013年 | 109篇 |
2012年 | 44篇 |
2011年 | 36篇 |
2010年 | 76篇 |
2009年 | 108篇 |
2008年 | 41篇 |
2007年 | 44篇 |
2006年 | 42篇 |
2005年 | 25篇 |
2004年 | 13篇 |
2003年 | 10篇 |
2002年 | 14篇 |
2001年 | 29篇 |
2000年 | 12篇 |
1999年 | 24篇 |
1998年 | 80篇 |
1997年 | 95篇 |
1996年 | 78篇 |
1995年 | 68篇 |
1994年 | 49篇 |
1993年 | 52篇 |
1992年 | 26篇 |
1991年 | 14篇 |
1990年 | 25篇 |
1989年 | 52篇 |
1988年 | 42篇 |
1987年 | 26篇 |
1986年 | 20篇 |
1985年 | 20篇 |
1984年 | 16篇 |
1983年 | 9篇 |
1982年 | 14篇 |
1981年 | 14篇 |
1980年 | 14篇 |
1979年 | 8篇 |
1978年 | 8篇 |
1977年 | 9篇 |
1976年 | 10篇 |
1971年 | 8篇 |
排序方式: 共有2011条查询结果,搜索用时 0 毫秒
951.
952.
Daniel B. Mark MD MPH J. David Knight MS Eric J. Velazquez MD Jaroslaw Wasilewski MD PhD Jonathan G. Howlett MD Peter K. Smith MD Miroslaw Rajda MD Rakesh Yadav DM Baron L. Hamman MD Marcin Malinowski MD Ajay Naik MD DM DNB Gena Rankin MPH Tina M. Harding RN BSN Laura A. Drew RN BSN Patrice Desvigne-Nickens MD Kevin J. Anstrom PhD STICH Investigators 《Journal of cardiac failure》2011,17(11):971-972
953.
Finn Gottrup MD DMSc Bo Jørgensen MD Tonny Karlsmark MD R. Gary Sibbald MD Rytis Rimdeika MD Keith Harding MB Patricia Price PhD Vanessa Venning DM Peter Vowden MD Michael Jünger MD Stephan Wortmann MD Rita Sulcaite MD PhD Gintaris Vilkevicius MD PhD Terttu‐Liisa Ahokas MD Karel Ettler MD PhD Monika Arenbergerova MD PhD 《Wound repair and regeneration》2008,16(5):615-625
Six out of 10 patients with chronic wounds suffer from persistent wound pain. A multinational and multicenter randomized double‐blind clinical investigation of 122 patients compared two moist wound healing dressings: a nonadhesive foam dressing with ibuprofen (62 patients randomized to Biatain Ibu Nonadhesive Coloplast A/S) and a nonadhesive foam without ibuprofen (60 patients to Biatain Non‐Adhesive—comparator). Patients were recruited from September 2005 to April 2006. The ibuprofen foam was considered successful if the pain relief on a five‐point Verbal Rating Scale was higher than the comparator without compromising safety including appropriate healing rate. Additional endpoints were change in persistent wound pain between dressing changes and pain at dressing change on days 1–5 (double blind) and days 43–47 (single blind). The primary response variable, persistent pain relief, was significantly higher in the ibuprofen‐foam group, as compared with the comparator on day 1–5, with a quick onset of action (p<0.05). Wound pain intensity was significantly reduced with the ibuprofen foam during day 1–5 with 40% from baseline, compared with 30% with the comparator (p<0.001). At day 43–47, the patients in the ibuprofen‐foam group had a significant (p<0.05) reemergence of persistent pain and pain at dressing change (p<0.05) when the active dressing was changed to the comparator. Wound healing was similar in the ibuprofen foam and comparator group. No difference in adverse events between the comparator and the ibuprofen foam with local sustained release of low‐dose ibuprofen was observed in this study. It was generally found that women reported less pain intensity than men, and pain intensity decreased with increasing age. In addition, pain intensity increased with initial pain intensity and increasing wound size. This study has demonstrated that the ibuprofen‐foam dressing provided pain relief and reduced pain intensity without compromising healing or other safety parameters. 相似文献
954.
955.
DM Marcus 《Focus on Alternative and Complementary Therapies》2012,17(1):52-53
Miller E, Maimon Y, Rosenblatt Y et al. Delayed effect of acupuncture treatment in OA of the knee: a blinded, randomized, controlled trial. Evid Based Complement Altern Med 2011; Article ID 792975. doi:10.1093/ecam/nen080 相似文献
956.
Vasim Farooq MBChB MRCP Mamas A. Mamas BM BCh MA DPhil MRCP Farzin Fath‐Ordoubadi MD FRCP Douglas G. Fraser MB BChir DM 《Catheterization and cardiovascular interventions》2011,78(6):847-863
Aims : Prior coronary artery bypass graft (CABG) surgery is one of the main predictors of failure of transradial PCI. Frequently this is due to difficulty in graft cannulation and/or poor backup support. In addition to Proxis's? embolic protection role, the Proxis?, Heartrail?, and GuideLiner? guide catheter extension devices have all been shown to facilitate coronary intervention by increasing backup support and aiding stent delivery. We describe our institution's experiences using these devices to aid transradial graft intervention. Methods : Between October 2007 and March 2010, the utility and safety of these devices were assessed in consecutive transradial graft intervention procedures. Proxis? cases used for proximal protection alone were excluded. Deep intubation was defined as an intubation depth of ≥2cm. Results : Guide catheter extensions were used in 33 of 41 transradial graft interventions identified. Proxis? was used for proximal protection alone in 3 cases, leaving 30 cases as the study group (Heartrail? n = 18, GuideLiner? n = 3, Proxis? n = 9). In all study cases procedural success with final TIMI‐3 flow was achieved. Guide catheter extensions were used to aid during graft cannulation (n = 11), to improve backup support via deep intubation (n = 26) and as an adjunctive aspiration device (n = 11). Filter‐based distal embolic protection devices were used in 11/21 Heartrail? and GuideLiner? cases. Deep intubation depths ranged from 30 to 138 mm (mean 61 mm) with no complications related to deep intubation seen. Conclusions : The use of guide catheter extension systems facilitated transradial graft intervention via several mechanisms including aid to graft cannulation, increasing backup support, and as an adjunctive aspiration device. © 2011 Wiley Periodicals, Inc. 相似文献
957.
L Vazquez Y Nizamaldin C Combescure R Nedir M Bischof DM Dohan Ehrenfest J-P Carrel UC Belser 《Dento maxillo facial radiology》2013,42(2)
Objectives:
Conventional panoramic radiography, a widely used radiographic examination tool in implant treatment planning, allows evaluation of the available bone height before inserting posterior mandibular implants. Image distortion and vertical magnification due to projection geometry is well described for rotational panoramic radiographs. To assess the accuracy of vertical height measurements on direct digital panoramic radiographs, implants and metal balls positioned in the posterior mandible were used as radio-opaque reference objects. The reproducibility of the measuring method was assessed by the inter- and intraobserver agreements.Methods:
Direct digital panoramic radiographs, performed using a Kodak 8000C (Eastman Kodak Company, Rochester, NY), of 17 partially edentulous patients (10 females, 7 males, mean age 65 years) were selected from an X-ray database gathered during routine clinical evaluation of implant sites. Proprietary software and a mouse-driven calliper were used to measure the radiological length of 25 implants and 18 metal reference balls, positioned in mandibular posterior segments. The distortion ratio (DR) was calculated by dividing the radiological implant length by the implant''s real length and the radiological ball height by the ball''s real height.Results:
Mean vertical DR was 0.99 for implants and 0.97 for balls, and was unrelated to mandibular sites, side, age, gender or observer. Inter- and intraobserver agreements were acceptable for both reference objects.Conclusions:
Vertical measurements had acceptable accuracy and reproducibility when a software-based calibrated measurement tool was used, confirming that digital panoramic radiography can be reliably utilized to determine the pre-operative implant length in premolar and molar mandibular segments. 相似文献958.
Harmandeep Singh MD Abhinav Singhal MD Punit Sharma MD Chetan D. Patel MD Sandeep Seth DM Arun Malhotra PhD 《Journal of nuclear cardiology》2013,20(3):415-425
Background
Data on normal parameters of cardiac mechanical synchrony is limited, variable and obtained from small cohorts till date. In most studies, software used for such assessment has not been mentioned. The aim of study is to establish normal values of mechanical synchrony with equilibrium radionuclide angiography (ERNA) in a larger population using commercially available software.Methods
We retrospectively analysed ERNA studies of 108 patients having low pretest likelihood of coronary artery disease, no known history of cardiac disease, normal electrocardiogram and whose ERNA studies were considered normal by experienced observers. In addition, ten patients diagnosed with dilated cardiomyopathy (DCM) and having LVEF ≤ 40% underwent ERNA. Fourier first harmonic analysis of phase images was used to quantify synchrony parameters using commercially available software (XT-ERNA). Intraventricular synchrony for each ventricle was measured as the standard deviation of the LV and RV mean phase angles (SD LVmPA and SD RVmPA, respectively). Interventricular synchrony was measured as LV-RVmPA. Absolute interventricular delay was calculated as absolute difference between LV and RVmPA (without considering ± sign). All variables were expressed in milliseconds (ms) and degree (°). Intra-observer and inter-observer variabilities were assessed. Cut-off values for parameters were calculated from the normal database, and validated against patient group.Results
On phase analysis, LVmPA was observed to be 343 ± 48.5 milliseconds (174.7° ± 18.5°), SD LVmPA was 16.3 ± 5.4 milliseconds (8.2° ± 2.5°), RVmPA was 339 ± 50.4 milliseconds (171.8° ± 18.5°) and SD RVmPA was 37.3 ± 15.7 milliseconds (18.7° ± 7.2°). LV-RVmPA was observed to be 3.9 ± 21.7 milliseconds (2.9° ± 9.6°) and absolute interventricular delay was 16.3 ± 14.8 milliseconds (7.9° ± 6.1°). The cut-off values for the presence of dyssynchrony were estimated as SD LVmPA > 27.1 milliseconds (>13.2°), SD RVmPA > 68.7 milliseconds (>33.1°) and LV-RVmPA > 47.3 milliseconds (>22.1°). There was no statistically significant intra-observer or inter-observer variability. Using these cut offs, 9 patients with DCM showed the presence of left intraventricular dyssynchrony, 5 had right intraventricular dyssynchrony and 2 had interventricular dyssynchrony.Conclusions
ERNA phase analysis offers an objective and reproducible tool to quantify cardiac mechanical synchrony using commercially available software and can be used in routine clinical practice to assess mechanical dyssynchrony. 相似文献959.
Tinea capitis in south-western Ethiopia: a study of risk factors for infection and carriage 总被引:1,自引:0,他引:1
Jose Ignacio Figueroa MD PhD Thomas Hawranek MD Aynalem Abraha MD Roderick James Hay DM FRCP FRCPath 《International journal of dermatology》1997,36(9):661-666
Background Tinea capitis is a common dermatophyte infection which constitutes an important public health problem among children worldwide. The endemic nature of scalp ringworm in Africa is perpetuated mainly by the lack of knowledge about the prevalence and carrier status, and the absence of control measures. Methods Two hundred and nineteen schoolchildren from urban and rural communities of the Illubabor district, south-western Ethiopia, were examined, and scalp samples were taken. Children were classified according to clinical signs and mycologic findings. Results Physical examination revealed that 29% of the children had clinical lesions compatible with tinea capitis. Dermatophytes were isolated from 33% of the children's scalp samples; of these, 16% had clinical lesions and 17% were identified as carriers. Trichophyton violaceum was responsible for 97% of infections. Conclusions Tinea capitis was the second most prevalent cutaneous finding in these children, with a higher prevalence in the urban community; the predictive value of the clinical diagnosis was low and a high proportion of children were identified as carriers in these communities. No relationship between household overcrowding and scalp infection was found. 相似文献
960.