全文获取类型
收费全文 | 6386篇 |
免费 | 493篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 28篇 |
儿科学 | 155篇 |
妇产科学 | 87篇 |
基础医学 | 807篇 |
口腔科学 | 221篇 |
临床医学 | 639篇 |
内科学 | 1367篇 |
皮肤病学 | 72篇 |
神经病学 | 398篇 |
特种医学 | 216篇 |
外科学 | 1017篇 |
综合类 | 166篇 |
一般理论 | 4篇 |
预防医学 | 484篇 |
眼科学 | 224篇 |
药学 | 425篇 |
中国医学 | 4篇 |
肿瘤学 | 580篇 |
出版年
2024年 | 13篇 |
2023年 | 79篇 |
2022年 | 115篇 |
2021年 | 246篇 |
2020年 | 121篇 |
2019年 | 214篇 |
2018年 | 239篇 |
2017年 | 168篇 |
2016年 | 180篇 |
2015年 | 191篇 |
2014年 | 288篇 |
2013年 | 321篇 |
2012年 | 521篇 |
2011年 | 500篇 |
2010年 | 297篇 |
2009年 | 221篇 |
2008年 | 352篇 |
2007年 | 390篇 |
2006年 | 313篇 |
2005年 | 330篇 |
2004年 | 330篇 |
2003年 | 278篇 |
2002年 | 254篇 |
2001年 | 94篇 |
2000年 | 94篇 |
1999年 | 79篇 |
1998年 | 58篇 |
1997年 | 37篇 |
1996年 | 33篇 |
1995年 | 17篇 |
1994年 | 29篇 |
1993年 | 16篇 |
1992年 | 33篇 |
1991年 | 38篇 |
1990年 | 55篇 |
1989年 | 35篇 |
1988年 | 31篇 |
1987年 | 34篇 |
1986年 | 33篇 |
1985年 | 31篇 |
1984年 | 27篇 |
1983年 | 18篇 |
1982年 | 12篇 |
1981年 | 8篇 |
1980年 | 8篇 |
1979年 | 33篇 |
1977年 | 14篇 |
1974年 | 7篇 |
1972年 | 11篇 |
1971年 | 9篇 |
排序方式: 共有6894条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
Darren R. Feldman MD Yasser Ged MBBS Chung-Han Lee PhD Andrea Knezevic MS Ana M. Molina MD Ying-Bei Chen PhD Joshua Chaim DO Devyn T. Coskey MS Samuel Murray MS Satish K. Tickoo MD Victor E. Reuter MD Sujata Patil PhD Han Xiao MD Jahan Aghalar MD Arlyn J. Apollo MD Maria I. Carlo MD Robert J. Motzer MD Martin H. Voss MD 《Cancer》2020,126(24):5247-5255
7.
Treatment of thrombocytopenia with alfa interferon 总被引:1,自引:0,他引:1
A M Lever M G Brook I Yap H C Thomas 《British medical journal (Clinical research ed.)》1987,295(6612):1519-1520
8.
9.
Role of cell-cell contact in the preservation of differentiation and response to thyrotrophin in cultured porcine thyroid cells 总被引:2,自引:0,他引:2
Cultured porcine thyroid cells did not reassociate into functional follicles in the presence of TSH unless the initial seeding density was adequate. At 0.2 X 10(6) cells/35 mm diameter culture dish the cells rapidly formed a monolayer even in the presence of TSH (128 microunits./ml), and radioiodide uptake was not significantly increased compared with that in control cells. Seeding densities of 1-3 X 10(6) cells/dish resulted in cultures which responded to TSH with follicular development and increased radioiodide uptake. A cell-free membrane fraction of thyroid homogenate restored the ability of cultures seeded at low densities to respond to TSH with development of follicular morphology and increased radioiodide uptake. Delaying the addition of TSH by 48 h markedly reduced the stimulation of follicular development and radioiodide uptake of cultures. Addition of membrane fractions, or an alkali-soluble fraction of membranes, at zero time improved the responses to TSH added after a 48-h delay. It was concluded that maintenance of differentiation and of TSH-responsiveness in cultured thyroid cells was influenced by cell-cell contact. 相似文献
10.
Acellular Pertussis Vaccine Protects against Exacerbation of Allergic Asthma Due to Bordetella pertussis in a Murine Model 下载免费PDF全文
Darren P. Ennis Joseph P. Cassidy Bernard P. Mahon 《Clinical and Vaccine Immunology : CVI》2005,12(3):409-417
The prevalence of asthma and allergic disease has increased in many countries, and there has been speculation that immunization promotes allergic sensitization. Bordetella pertussis infection exacerbates allergic asthmatic responses. We investigated whether acellular pertussis vaccine (Pa) enhanced or prevented B. pertussis-induced exacerbation of allergic asthma. Groups of mice were immunized with Pa, infected with B. pertussis, and/or sensitized to ovalbumin. Immunological, pathological, and physiological changes were measured to assess the impact of immunization on immune deviation and airway function. We demonstrate that immunization did not enhance ovalbumin-specific serum immunoglobulin E production. Histopathological examination revealed that immunization reduced the severity of airway pathology associated with sensitization in the context of infection and decreased bronchial hyperreactivity upon methacholine exposure of infected and sensitized mice. These data demonstrate unequivocally the benefit of Pa immunization to health and justify selection of Pa in mass vaccination protocols. In the absence of infection, the Pa used in this study enhanced the interleukin-10 (IL-10) and IL-13 responses and influenced airway hyperresponsiveness to sensitizing antigen; however, these data do not suggest that Pa contributes to childhood asthma overall. On the contrary, wild-type virulent B. pertussis is still circulating in most countries, and our data suggest that the major influence of Pa is to protect against the powerful exacerbation of asthma-like pathology induced by B. pertussis. 相似文献