全文获取类型
收费全文 | 4388篇 |
免费 | 204篇 |
国内免费 | 34篇 |
专业分类
耳鼻咽喉 | 117篇 |
儿科学 | 183篇 |
妇产科学 | 210篇 |
基础医学 | 338篇 |
口腔科学 | 150篇 |
临床医学 | 411篇 |
内科学 | 1010篇 |
皮肤病学 | 164篇 |
神经病学 | 277篇 |
特种医学 | 191篇 |
外科学 | 973篇 |
综合类 | 66篇 |
预防医学 | 97篇 |
眼科学 | 116篇 |
药学 | 156篇 |
中国医学 | 10篇 |
肿瘤学 | 157篇 |
出版年
2023年 | 36篇 |
2022年 | 66篇 |
2021年 | 100篇 |
2020年 | 82篇 |
2019年 | 90篇 |
2018年 | 134篇 |
2017年 | 104篇 |
2016年 | 171篇 |
2015年 | 160篇 |
2014年 | 178篇 |
2013年 | 278篇 |
2012年 | 316篇 |
2011年 | 333篇 |
2010年 | 199篇 |
2009年 | 154篇 |
2008年 | 298篇 |
2007年 | 318篇 |
2006年 | 280篇 |
2005年 | 291篇 |
2004年 | 227篇 |
2003年 | 194篇 |
2002年 | 167篇 |
2001年 | 109篇 |
2000年 | 69篇 |
1999年 | 62篇 |
1998年 | 28篇 |
1997年 | 12篇 |
1996年 | 14篇 |
1995年 | 8篇 |
1994年 | 10篇 |
1993年 | 9篇 |
1992年 | 18篇 |
1991年 | 8篇 |
1990年 | 11篇 |
1989年 | 8篇 |
1988年 | 10篇 |
1987年 | 10篇 |
1986年 | 6篇 |
1985年 | 7篇 |
1984年 | 7篇 |
1980年 | 3篇 |
1979年 | 5篇 |
1974年 | 3篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1970年 | 3篇 |
1969年 | 2篇 |
1967年 | 6篇 |
1966年 | 3篇 |
1909年 | 2篇 |
排序方式: 共有4626条查询结果,搜索用时 31 毫秒
21.
Ersoy Acer Hilal Kaya Erdoğan Nihan Yüksel Çanakçı Zeynep Nurhan Saracoğlu 《Cutaneous and ocular toxicology》2020,39(2)
AbstractWe read Cosansu’s commentary entitled “Effectiveness of the new inflammatory parameters in patients with chronic spontaneous urticarial” to our study with great interest. The author remarked that a limited number of patients had C-reactive protein levels and it was not specified whether there were any other drugs used by the patients and no information was given about the severity of the disease in our study. 相似文献
22.
Attila akmak Yasemin irpanli Erem Bilensoy Kaya Yorganci Sema ali Zeynep Sariba Volkan Kaynarolu 《International journal of pharmaceutics》2009,381(2):214-Systems
The use of mesh in hernia repair has become common, because of lower recurrence rate and simple application. Data from the meta-analysis and the multi-central studies support the use of meshes in hernia repair. One of the complications due to the hernia repair with mesh is the infection. The incidence range is between 1 and 10%. Triclosan embedded commercial absorbable suture materials are used to reduce surgical site infection rate. This study was planned on mesh infection model, because of the low incidence rate. The agent isolated from mesh infections was mostly Staphylococcus aureus and thus it was used as the infecting agent in this research. To achieve a better therapeutic efficacy, triclosan was formulated in chitosan gels. Chitosan is an attractive biopolymer because of its biocompatible, biodegradable, bioadhesive properties. Gel formulations using chitosans (low, medium and high molecular weight) were prepared in 1% (v/v) acetic acid solution and in vitro release profiles were evaluated. Gel formulations showed release profile extended up to 7 days and high molecular weight chitosan gel formulation was released higher quantity drug than other formulations. Meshes coated with triclosan loaded chitosan gel were used to reduce bacterial count and to prevent mesh infection in the study. 24 h and simultaneous bacteria inoculation was used to model mesh infection. The rats were observed for 8 days by means of surgical site infection. On the eighth day, the animals were sacrificed and the grafts were removed. Tissue squeezers were used to liberate bacterias from removed grafts. The isolated suspensions were cultured on blood agar plates and colony-forming units were counted overnight. Grafts coated with triclosan loaded chitosan gel presented satisfactory preventive effect against graft infection. 相似文献
23.
24.
Coskun A Ozdemir O Vardar MA Kiran G Arikan D Ersoz C 《Clinical and experimental obstetrics & gynecology》2008,35(3):227-230
Leiomyomas and diffuse uterine leiomyomatosis are smooth muscle tumors of the uterus. Diffuse uterine leiomyomatosis is a benign and extremely rare condition in which the uterus is symmetrically enlarged as a result of the almost complete replacement of the myometrium by innumerable poorly defined, confluent nodules. The etiology of these neoplasms is not completely understood. Initial symptoms of the diffuse uterine leiomyomatosis usually are abdominal pain and abnormal uterine bleeding. Similar to uterine leiomyomas, patients with leiomyomatosis present with menorrhagia, dysmenorrhea, abdominal pain, infertility, and pelvic pressure. Hormonal treatment usually fails to control the symptoms, anemia, or tumor growth after treatment is stopped. As a result, despite patients being in the third or fourth decades of life, hysterectomy has been the only permanent treatment option offered to patients for treatment of the symptoms related to uterine fibroids in diffuse leiomyomatosis. A case of a patient with a huge uterine mass (2,650 g in weight) who underwent hysterectomy due to diffuse uterine leiomyomatosis is presented together with a review of the literature. 相似文献
25.
26.
Dr. med. R. Kaya 《Virchows Archiv : an international journal of pathology》1907,189(3):466-512
Ohne ZusammenfassungHierzu drei Textabbildungen und Taf. XIV. 相似文献
27.
Blythe A. Layton Devrim Kaya Christine Kelly Kenneth J. Williamson Dana Alegre Silke M. Bachhuber Peter G. Banwarth Jeffrey W. Bethel Katherine Carter Benjamin D. Dalziel Mark Dasenko Matthew Geniza Andrea George Anne-Marie Girard Roy Haggerty Kathryn A. Higley Denise M. Hynes Jane Lubchenco Katherine R. McLaughlin F. Javier Nieto Aslan Noakes Matthew Peterson Adriana D. Piemonti Justin L. Sanders Brett M. Tyler Tyler S. Radniecki 《Environmental health perspectives》2022,130(6)
Background: Positive correlations have been reported between wastewater SARS-CoV-2 concentrations and a community’s burden of infection, disease or both. However, previous studies mostly compared wastewater to clinical case counts or nonrepresentative convenience samples, limiting their quantitative potential.Objectives: This study examined whether wastewater SARS-CoV-2 concentrations could provide better estimations for SARS-CoV-2 community prevalence than reported cases of COVID-19. In addition, this study tested whether wastewater-based epidemiology methods could identify neighborhood-level COVID-19 hotspots and SARS-CoV-2 variants.Methods: Community SARS-CoV-2 prevalence was estimated from eight randomized door-to-door nasal swab sampling events in six Oregon communities of disparate size, location, and demography over a 10-month period. Simultaneously, wastewater SARS-CoV-2 concentrations were quantified at each community’s wastewater treatment plant and from 22 Newport, Oregon, neighborhoods. SARS-CoV-2 RNA was sequenced from all positive wastewater and nasal swab samples. Clinically reported case counts were obtained from the Oregon Health Authority.Results: Estimated community SARS-CoV-2 prevalence ranged from 8 to 1,687/10,000 persons. Community wastewater SARS-CoV-2 concentrations ranged from 2.9 to gene copies per liter. Wastewater SARS-CoV-2 concentrations were more highly correlated (Pearson’s ; ) with community prevalence than were clinically reported cases of COVID-19 (Pearson’s ; ). Monte Carlo simulations indicated that wastewater SARS-CoV-2 concentrations were significantly better than clinically reported cases at estimating prevalence (). In addition, wastewater analyses determined neighborhood-level COVID-19 hot spots and identified SARS-CoV-2 variants (B.1 and B.1.399) at the neighborhood and city scales.Discussion: The greater reliability of wastewater SARS-CoV-2 concentrations over clinically reported case counts was likely due to systematic biases that affect reported case counts, including variations in access to testing and underreporting of asymptomatic cases. With these advantages, combined with scalability and low costs, wastewater-based epidemiology can be a key component in public health surveillance of COVID-19 and other communicable infections. https://doi.org/10.1289/ EHP10289相似文献
28.
29.
30.
M. Erkoçoğlu A. Kaya D. Azkur Ş. Özyer C. Özcan M. Beşli E. Civelek C.N. Kocabaş 《Allergologia et immunopathologia》2013,41(3):169-175
BackgroundEmerging evidence suggests that sex steroid hormones may influence respiratory symptoms. The existing literature about the role of oral contraceptive pill (OCP) on respiratory disease is scarce and conflicting especially during the adolescent period. In this study, we aimed to investigate the effect of OCPs on current wheezing among adolescents and young adults.MethodsA questionnaire was administered face-to-face to adolescents and young women by a physician. The questionnaire included ISAAC survey-comprised questions on ever wheezing, current wheezing, allergic diseases, smoking history (active or passive), and family history of allergic diseases and questions on OCP usage status. The effect of OCPs on wheezing was evaluated by logistic regression analysis.ResultsA total of 487 subjects aged between 11.3 and 25.6 years participated in the study and 196 (40.2%) reported that they had used OCPs. 7.4% of the participants had physician-diagnosed asthma and 10.3% of them were active smokers. It was detected that OCPs were associated with increased risk for current wheezing (odds ratio, 2.36; 95% CI, 1.25–4.47 adjusted for asthma and current smoker) and this risk was related with the usage during the past year.ConclusionYoung women taking oral contraceptives had a higher rate of current wheezing, suggesting that sex steroids may be of importance for respiratory health. 相似文献