全文获取类型
收费全文 | 216789篇 |
免费 | 5245篇 |
国内免费 | 3096篇 |
专业分类
耳鼻咽喉 | 1530篇 |
儿科学 | 7234篇 |
妇产科学 | 3762篇 |
基础医学 | 20744篇 |
口腔科学 | 2279篇 |
临床医学 | 17643篇 |
内科学 | 36552篇 |
皮肤病学 | 1085篇 |
神经病学 | 18477篇 |
特种医学 | 10452篇 |
外国民族医学 | 22篇 |
外科学 | 33608篇 |
综合类 | 9987篇 |
现状与发展 | 9篇 |
一般理论 | 5篇 |
预防医学 | 21241篇 |
眼科学 | 3553篇 |
药学 | 13826篇 |
45篇 | |
中国医学 | 3383篇 |
肿瘤学 | 19693篇 |
出版年
2024年 | 193篇 |
2023年 | 808篇 |
2022年 | 1946篇 |
2021年 | 2558篇 |
2020年 | 1873篇 |
2019年 | 1555篇 |
2018年 | 23402篇 |
2017年 | 18803篇 |
2016年 | 20812篇 |
2015年 | 3029篇 |
2014年 | 3358篇 |
2013年 | 3313篇 |
2012年 | 10435篇 |
2011年 | 24548篇 |
2010年 | 21203篇 |
2009年 | 13491篇 |
2008年 | 21735篇 |
2007年 | 23761篇 |
2006年 | 2478篇 |
2005年 | 3967篇 |
2004年 | 4552篇 |
2003年 | 5509篇 |
2002年 | 3514篇 |
2001年 | 1108篇 |
2000年 | 1196篇 |
1999年 | 906篇 |
1998年 | 594篇 |
1997年 | 606篇 |
1996年 | 405篇 |
1995年 | 405篇 |
1994年 | 341篇 |
1993年 | 213篇 |
1992年 | 272篇 |
1991年 | 269篇 |
1990年 | 289篇 |
1989年 | 224篇 |
1988年 | 191篇 |
1987年 | 175篇 |
1986年 | 124篇 |
1985年 | 117篇 |
1984年 | 69篇 |
1983年 | 57篇 |
1982年 | 40篇 |
1980年 | 63篇 |
1974年 | 28篇 |
1970年 | 30篇 |
1938年 | 60篇 |
1934年 | 30篇 |
1932年 | 56篇 |
1930年 | 48篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
Kimihiro Shimizu Yoshimi Otani Takashi Ibe Osamu Kawashima Mituhiro Kamiyoshihara Yasuo Morishita 《General thoracic and cardiovascular surgery》2005,53(1):39-41
Late-onset chylothorax occurred 49 days after right lower lobectomy for lung cancer in a 76-year-old man. Chylothorax was successfully managed by conservative treatment with chest tube drainage and an enteral low-fat diet. Chylothorax may occur in the late period after pulmonary resection and systematic mediastinal lymph node dissection for lung cancer, for which conservative management is the treatment of choice. 相似文献
102.
小脑后下动脉动脉瘤的诊断和治疗 总被引:1,自引:0,他引:1
目的探讨小脑后下动脉动脉瘤的临床特征、诊断、鉴别诊断和治疗。方法回顾性分析12例小脑后下动脉瘤的临床表现、影像学特征、手术效果及诊治过程中存在的相关问题。结果12例中有11例因动脉瘤破裂出血而发病,单纯第四脑室出血4例,全脑室系统出血2例,小脑半球出血3例,小脑蚓部伴第四脑室出血1例,侧脑室伴第三脑室出血1例,以后颅窝占位病变表现1例。8例术前行DSA检查明确诊断,4例术中明确诊断。12例均行后颅窝开颅显微手术治疗,其中动脉瘤颈夹闭9例,孤立切除2例,动脉瘤加固术1例,术后2例因脑积水加重行脑室-腹腔分流术。12例中除1例术后留有轻偏瘫外,其余11例恢复良好。结论小脑后下动脉瘤多以第四脑室出血发病,少数以小脑半球或蚓部出血发病,及早治疗效果满意。手术方式应尽量夹闭动脉瘤颈,对于小脑后下动脉末端动脉瘤,可以采用孤立切除术。 相似文献
103.
Scarlett Lin Gomez Cynthia D O'Malley Antoinette Stroup Sarah J Shema William A Satariano 《BMC cancer》2007,7(1):193
Background
Colorectal cancer, if detected early, has greater than 90% 5-year survival. However, survival has been shown to vary across racial/ethnic groups in the United States, despite the availability of early detection methods. 相似文献104.
Carmen Guillén Ponce María Pilar Garrido López María José Molina Garrido Gema Muñoz Molina Alfredo Carrato 《Clinical & translational oncology》2007,9(1):53-55
Pituitary metastases of solid tumours are infrequent, specially as a first manifestation. When they happen, they are usually
due to breast or lung cancer and are asymptomatic or produce diabetes insipidus. It is very strange that they produce hormonal
deficiency.
We present a case report of a bronchogenic adenocarcinoma in a 65-year-old man which began with panhypopituitarism, diabetes
insipidus and visual alterations. Magnetic resonance imaging revealed a large sellar mass, with clivus infiltration and invading
the right cavernous sinus. The biopsy result was adenocarcinoma metastases from lung cancer. 相似文献
105.
Ricardo J. Wray Jo Ellen Stryker Eric Winer George Demetri Karen M. Emmons 《Journal of cancer education》2007,22(1):21-24
Background. Accepted practices of informed consent often result in suboptimal patient understanding of research studies.Methods. This pilot study aimed to assess trial-specific tailored materials, compared to a widely used generic booklet about clinical
trials, randomly assigned to 118 candidates for cancer clinical trials. Study outcomes were: satisfaction with decision-making;
satisfaction with materials; and subjective understanding of the clinical trial.Results. There were no major differences between groups. Participants rated tailored materials higher as a useful reference.Conclusions. Trial-specific materials hold utility for reference during clinical trials. Studies of informed consent are feasible, although
important factors limit research. 相似文献
106.
Lei Wang Moyi Sun Yuegui Jiang Lianjia Yang Delin Lei Chao Lu Yinghua Zhao Pu Zhang Yaowu Yang Jianhu Li 《Journal of oral and maxillofacial surgery》2006,64(4):636-641
PURPOSE: Perineural invasion is a frequent occurrence in salivary adenoid cystic carcinoma (ACC) and may prevent complete surgical resection. Studies have indicated that nerve growth factor (NGF) and its high-affinity receptor tyrosine kinase A (TrkA) may play a role in perineural invasion in several malignancies in which perineural invasion is observed. The present study was conducted to investigate the expression of NGF and TrkA in salivary ACC and to examine the effects of NGF on adhesion, migration and invasion capacities of a salivary ACC cell line (SACC-83) in vitro. PATIENTS AND METHODS: Expression of NGF and TrkA was explored using immunohistochemistry in paraffin-embedded tissues of 32 cases of salivary ACC. The effects of NGF on in vitro adhesion, migration, and invasion capacities of the SACC-83 cell line were examined using an MTT assay and a modified Boyden chamber assay respectively. RESULTS: In ACC specimens, 31 (96.9%) and 32 (100%) tumors showed immunoreactivity for NGF and TrkA respectively. Significant correlations were found between NGF/TrkA expression levels and perineural invasion (P < .05). In cell adhesion assay, the percent adherences of SACC-83 cells co-cultured with 25 ng/ml NGF at 1.5 hours and 5, 25 ng/ml NGF at 6 hours were significantly higher than that co-cultured with 0 ng/ml NGF (P < .05). However, high concentration of NGF (500 ng/ml) resulted in a significant inhibition of invasion (P < .05). CONCLUSION: Overexpression of NGF and TrkA in human salivary ACC tissues may constitute a reason for perineural invasion in salivary ACC. 相似文献
107.
Ramona A. Cole Anita Bansal Debra M. Moriarity William A. Haber William N. Setzer 《Journal of natural medicines》2007,61(4):414-417
The leaf essential oil of Eugenia zuchowskiae from Monteverde, Costa Rica, has been obtained by hydrodistillation and analyzed by GC–MS. The principal constituents of
E. zuchowskiae leaf oil were α-pinene (28.3%), β-caryophyllene (13.2%), α-humulene (13.1%), and α-copaene (8.1%). The leaf essential oil
of E. zuchowskiae showed pronounced in-vitro cytotoxic activity against MCF-7, MDA-MB-468, and UACC-257 human tumor cell lines. The major components
showed cytotoxic activities comparable to doxorubicin (LC50 14–70 μg/ml). 相似文献
108.
109.
采用核桃仁泥外敷治疗138例(实验组)肌肉注射后皮下硬结,并与40例(对照组)采用新鲜土豆片外敷硬结法比较。结果表明:实验组患者治疗15天后Ⅰ度和Ⅱ度硬结治愈率分别为81.13%和42.25%,总有效率达92.03%,明显优于对照组(P<0.001)。 相似文献
110.