Amisulpride induced mania

Amisulpride is an atypical antipsychotic used for the management of schizophrenia and other conditions like dysthymia. It has also been used for the management of bipolar disorders as an add on therapy. Here, we report a patient of schizophrenia who developed a manic episode while on amisulpride.     

Isolation by crystallization of translational isomers of a bistable donor-acceptor [2]catenane

The template-directed synthesis of a bistable donor-acceptor [2]catenane wherein both translational isomers—one in which a tetrathiafulvalene unit in a mechanically interlocked crown ether occupies the cavity of a cyclobis(paraquat-p-phenylene) ring and the other in which a 1,5-dioxynaphthalene unit in the crown ether resides inside the cavity of the tetracationic cyclophane—exist in equilibrium in solution, has led to the isolation and separation by hand picking of single crystals colored red and green, respectively. These two crystalline co-conformations have been characterized separately at both the molecular and supramolecular levels, and also by dynamic NMR spectroscopy in solution where there is compelling evidence that the mechanically interlocked molecules are present as a complex mixture of translational, configurational, and conformational isomers wherein the isomerization is best described as being a highly dynamic and adaptable phenomenon.     

A retrospective analysis of 189 patients of maxillofacial injuries presenting to a tertiary care hospital in Punjab, India

Introduction  

Maxillofacial injuries form a major aspect of trauma management in trauma centers. Prompt diagnosis and management is needed to provide better quality of life and cosmetic results as compared to delayed interventions.     

Tracheostomy in critically ill patients

ENT surgeons are called in more often these days to perform tracheostomy in critically ill patients. When to perform tracheostomy is a question, which is most often asked. There are definite advantages for performing tracheostomy at an early stage of intensive care, but at the same time we need to be aware of the possible complications that are associated with it. Tracheal stenosis being one of the most common complications, which can be prevented if proper care is taken from the time tracheostomy is done.     

International Emergency Medicine: A Review of the Literature from 2006

The field of international emergency medicine (IEM) has grown rapidly over the past several decades, with a rise in the number of IEM fellowship positions, sustained growth in the international sections of major emergency medicine organizations, and an increase in the range of topics included under its rubric. One of the greatest obstacles to the continued growth of IEM remains the lack of a high-quality, consolidated, and easily accessible evidence base of literature. In response to this perceived need, members of the Emergency Medicine Residents' Association IEM Committee, in conjunction with members of the Society for Academic Emergency Medicine International Health Interest Group, embarked on the task of creating a recurring review of IEM literature. This article reviews 25 IEM research articles published in 2006. Research articles were selected for the review according to explicit, predetermined criteria that included both methodological quality and perceived impact of the research. It is the authors' hope that this annual review will act as a forum for disseminating best practices while also stimulating further research in the field of IEM.