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71.
Alessandra Mazzo José Carlos Amado Martins Beatriz Maria Jorge Rui Carlos Negr?o Batista Rodrigo Guimar?es dos Santos Almeida Fernando Manuel Dias Henriques Verónica Rita Dias Coutinho Isabel Amélia Costa Mendes 《Revista latino-americana de enfermagem》2015,23(5):814-820
Objective:
to validate an instrument to measure self-confidence of nursing care in urinary retention.Methods:
methodological research study, carried out after ethical approval. A Likert-like scale of 32 items related to nursing care in urinary retention was applied to students of the graduate nursing course. For instrument validation, analysis of the sample adequacy and main components, Varimax orthogonal rotation and internal consistency analyses were developed.Results:
in a sample of 305 students, there was high correlation of all items with the total scale and Cronbach''s alpha of 0.949. The scale items were divided into five factors with internal consistency: Factor 1 (0.890), Factor 2 (0.874), Factor 3 (0.868), Factor 4 (0.814) and Factor 5 (0.773), respectively.Conclusion:
the scale meets the validity requirements, demonstrating potential for use in evaluation and research. 相似文献72.
73.
Fernando G. Zampieri Theodore J. Iwashyna Elizabeth M. Viglianti Leandro U. Taniguchi William N. Viana Roberto Costa Thiago D. Corrêa Carlos Eduardo N. Moreira Marcelo O. Maia Giulliana M. Moralez Thiago Lisboa Marcus A. Ferez Carlos Eduardo F. Freitas Clayton B. de Carvalho Bruno F. Mazza Mariza F. A. Lima Grazielle V. Ramos Aline R. Silva Fernando A. Bozza Jorge. I. F. Salluh Marcio Soares for the ORCHESTRA Study Investigators 《Intensive care medicine》2018,44(9):1512-1520
Purpose
Frail patients are known to experience poor outcomes. Nevertheless, we know less about how frailty manifests itself in patients’ physiology during critical illness and how it affects resource use in intensive care units (ICU). We aimed to assess the association of frailty with short-term outcomes and organ support used by critically ill patients.Methods
Retrospective analysis of prospective collected data from 93 ICUs in Brazil from 2014 to 2015. We assessed frailty using the modified frailty index (MFI). The primary outcome was in-hospital mortality. Secondary outcomes were discharge home without need for nursing care, ICU and hospital length of stay (LOS), and utilization of ICU organ support and transfusion. We used mixed logistic regression and competing risk models accounting for relevant confounders in outcome analyses.Results
The analysis consisted of 129,680 eligible patients. There were 40,779 (31.4%) non-frail (MFI?=?0), 64,407 (49.7%) pre-frail (MFI?=?1–2) and 24,494 (18.9%) frail (MFI?≥?3) patients. After adjusted analysis, frailty was associated with higher in-hospital mortality (OR 2.42, 95% CI 1.89–3.08), particularly in patients admitted with lower SOFA scores. Frail patients were less likely to be discharged home (OR 0.36, 95% CI 0.54–0.79) and had higher hospital and ICU LOS than non-frail patients. Use of all forms of organ support (mechanical ventilation, non-invasive ventilation, vasopressors, dialysis and transfusions) were more common in frail patients and increased as MFI increased.Conclusions
Frailty, as assessed by MFI, was associated with several patient-centered endpoints including not only survival, but also ICU LOS and organ support.74.
75.
76.
Rodolfo Gonzalez Camargo Daniela Mendes dos Reis Riccardi Henrique Quintas Teixeira Ribeiro Luiz Carlos Carnevali Jr. Emidio Marques de Matos-Neto Lucas Enjiu Rodrigo Xavier Neves Joanna Darck Carola Correia Lima Raquel Galv?o Figuerêdo Paulo Sérgio Martins de Alcantara Linda Maximiano José Otoch Miguel Luiz Batista Jr. Gerhard Püschel Marilia Seelaender 《Nutrients》2015,7(6):4465-4479
77.
Vale Paula D. Silva Livia T. M. de Oliveira Edna Maria M. de Miranda Ricardo F. C. da Silva Renato David Araújo Lielia M. C. da Silva Samuel M. P. Cunha Wanessa C. Neto José S. Péres Ayrton K. Seixas Tamer N. da Rocha Jairo M. Margalho Carla S. Maia Henrique Cesar de A. 《Journal of interventional cardiac electrophysiology》2022,63(2):425-430
Journal of Interventional Cardiac Electrophysiology - Delineate retrospectively and prospectively the incidence and characteristics of transient ST-segment elevation during transseptal puncture.... 相似文献
78.
Rodrigues AM Radominski RB Suplicy Hde L De Almeida SM Niclewicz PA Boguszewski CL 《The Journal of clinical endocrinology and metabolism》2002,87(4):1621-1626
The aim of the present study was to evaluate the cerebrospinal fluid (CSF)/serum leptin ratio during pharmacological therapy for obesity with centrally and peripherally acting drugs. Thirty-one obese women (mean age, 32.3 +/- 10 yr; body mass index, 38.2 +/- 5.2 kg/m(2); body fat, 43.3 +/- 5.4%) were studied before and 2 months after a weight loss program consisting of a balanced diet (1200 kcal/d) plus drug therapy. The patients were randomly assigned into three study groups: group I, fenproporex 25 mg/d (n = 10); group II, sibutramine 10 mg/d (n = 10); and group III, orlistat 120 mg tid (n = 11). Body fat, measured by dual-energy x-ray absorptiometry, and serum and CSF concentrations of leptin were examined at baseline and 2 months after therapy. At baseline, clinical and biochemical characteristics of the groups were similar. All of the women lost weight, approximately 7.0% of their initial body weight, and the reduction was not different among the groups. Serum leptin fell significantly after 2 months in all groups, and the decline was proportional to the reduction in body fat, because leptin levels adjusted for body fat did not change after treatment. CSF leptin levels showed a significant decrease after 2 months in all groups, and this decline was higher on group III compared with group I (P = 0.006). After therapy, the CSF/serum leptin ratio did not change in group I (1.57 +/- 0.3 to 1.72 +/- 0.62%) and group II (1.78 +/- 1.01 to 1.69 +/- 1.27%), whereas it declined significantly in group III (1.65 +/- 0.43 to 1.09 +/- 0.47%; P < 0.01), corresponding to a decrease of 33.3 +/- 22.5% for the CSF/serum leptin ratio. The percentage change in group III was significantly different from the positive variation on group I (11.9 +/- 42.1%; P = 0.006) and close to the statistical significance compared with the negative variation seen in group II (-7.6 +/- 27.8%; P = 0.06). Our results showed that the CSF/serum leptin ratio decreased after weight loss in obese women treated during 2 months with orlistat, whereas this ratio did not change in this period of time in obese women treated with fenproporex and sibutramine. 相似文献
79.
Oliveira Bruno R. R. Lattari Eduardo Pires Flávio O. Viana Bruno F. Machado Sérgio Rodrigues Guilherme M. Oliveira Izaildo A. Santos Tony M. 《Sport Sciences for Health》2022,18(1):211-217
Sport Sciences for Health - To compare the intensity and duration self-selected by participants with higher and lower cardiorespiratory fitness to that recommended by the American College of Sports... 相似文献
80.
Two melanocortin receptors MC2-R (ACTH-receptor) and MC5-R are expressed in the adult lamb adrenal cortex. In this work, we have studied the time-course of expression of these two receptors during ovine fetal development. MC2-R expression progressively increases from day 60 to day 140 of gestation (x3), then more rapidly before parturition and remains constant in the newborn. In contrast, the pattern of MC5-R expression is totally different. A strong increase is observed between days 60 and 120 (x7) then followed by a decrease until parturition and after birth. This peak of MC5-R expression precedes that of MC2-R, suggesting that MC5-R might be involved in alpha-MSH- and/or ACTH-stimulated corticosteroid synthesis during early embryonic life. 相似文献