全文获取类型
收费全文 | 6230篇 |
免费 | 395篇 |
国内免费 | 20篇 |
专业分类
耳鼻咽喉 | 108篇 |
儿科学 | 122篇 |
妇产科学 | 194篇 |
基础医学 | 835篇 |
口腔科学 | 765篇 |
临床医学 | 436篇 |
内科学 | 1165篇 |
皮肤病学 | 135篇 |
神经病学 | 494篇 |
特种医学 | 131篇 |
外科学 | 655篇 |
综合类 | 21篇 |
一般理论 | 4篇 |
预防医学 | 652篇 |
眼科学 | 157篇 |
药学 | 472篇 |
中国医学 | 74篇 |
肿瘤学 | 225篇 |
出版年
2023年 | 52篇 |
2022年 | 91篇 |
2021年 | 264篇 |
2020年 | 167篇 |
2019年 | 216篇 |
2018年 | 274篇 |
2017年 | 172篇 |
2016年 | 199篇 |
2015年 | 247篇 |
2014年 | 342篇 |
2013年 | 376篇 |
2012年 | 544篇 |
2011年 | 571篇 |
2010年 | 271篇 |
2009年 | 230篇 |
2008年 | 412篇 |
2007年 | 440篇 |
2006年 | 297篇 |
2005年 | 301篇 |
2004年 | 237篇 |
2003年 | 198篇 |
2002年 | 168篇 |
2001年 | 98篇 |
2000年 | 85篇 |
1999年 | 71篇 |
1998年 | 31篇 |
1997年 | 22篇 |
1996年 | 17篇 |
1995年 | 11篇 |
1994年 | 9篇 |
1993年 | 11篇 |
1992年 | 25篇 |
1991年 | 22篇 |
1990年 | 16篇 |
1989年 | 13篇 |
1988年 | 12篇 |
1987年 | 8篇 |
1986年 | 14篇 |
1985年 | 9篇 |
1983年 | 5篇 |
1979年 | 7篇 |
1978年 | 6篇 |
1977年 | 6篇 |
1976年 | 5篇 |
1974年 | 11篇 |
1973年 | 7篇 |
1971年 | 6篇 |
1970年 | 8篇 |
1969年 | 6篇 |
1968年 | 8篇 |
排序方式: 共有6645条查询结果,搜索用时 171 毫秒
61.
Costa Davidson Ribeiro Pessoa Diego Rodrigues Seefeldt Vanessa Borelli Costa David Ribeiro Maia Daniel Tineu Leite dos Santos Maciel Thiago Mota Brenda Barros Magalhães Delpasso Carolina Alves Ribeiro Camila Alves Delpasso Nicolau Renata Amadei 《Lasers in medical science》2021,36(8):1681-1689
Lasers in Medical Science - This study compared the effects of LED therapy associated with occlusal splint (OS) on the signs and symptoms of temporomandibular disorder (TMD). In this randomized,... 相似文献
62.
Daniela de Queiroz Moura Ramon Rawache Marília Ferreira Gomes Garcia Nathalia Farias Vasconcelos Priscila Santos Gustavo Rego Coelho Thiago Luis da Paz Santos Duílio Reis da Rocha Filho Sonia Leite da Silva Eliana Regia Barbosa de Almeida Paula F.C.B.C. Fernandes João Batista Cerqueira José Huygens Parente Garcia Claudia Maria Costa de Oliveira 《Transplantation proceedings》2021,53(4):1345-1349
Transplantation of any organ has some inherent risk of disease transmission, such as infection and malignancy. The present study aims to describe 2 cases of choriocarcinoma transmission after kidney and liver transplantation originating from the same patient. The donor was a 17-year-old woman who died of cerebral hemorrhage. Both organ recipients died of metastatic choriocarcinoma few months after the transplantation, within days after starting chemotherapy. Retrospective hCG (human chorionic gonadotropin hormone) analysis in donor's blood stored at the time of donation had a result of 9324 mIU/mL. Despite its rarity, clinicians should be aware of the risk of transplant-related choriocarcinoma from female donors in childbearing age. In some cases, hCG dosage should be performed before donation. 相似文献
63.
64.
65.
Gian Marco Moneta Claudia Bracaglia Ivan Caiello Chiara Farroni Denise Pires Marafon Raffella Carlomagno Linda Hiraki Marina Vivarelli Alessandra Gianviti Simone Carbogno Walter Ferlin Cristina de Min Earl Silverman Rita Carsetti Fabrizio De Benedetti Emiliano Marasco 《European journal of immunology》2023,53(7):2250319
66.
Jardim LB Martins CS Pires RF Sanseverino MT Refosco L Vieira Rde C Trotta Ede A Vargas C Neto EC Giugliani R 《Jornal de pediatria》1995,71(5):279-284
We report here the treatment and poor outcome of a case of Maple Syrup Urine Disease with late diagnosis and retrieval (2 and 5 months, respectively). As the proband had quite high levels of plasmatic leucine (1956 micromol/L for a normal upper limit of 77), we started immediately with a gluco-insulin therapy to produce anabolism in the infant. When leucine has fallen to 275.3 micromol/L, we instituted feeding with branched chain amino acid-free protein and high energy from carbohydrates. After reviewing briefly the clinical, biochemical and therapeutic aspects of this disorder, we comment on the great difficulties of making early diagnosis and of obtaining the specific dietetic formulas to Maple Syrup Urine Disease, in Brazil. 相似文献
67.
Mayan O Pires A Neves P Capela F 《Applied occupational and environmental hygiene》1999,14(11):785-790
Shoe manufacturing is a traditional industry in northern Portugal. There are nearly 1500 factories that employ about 54,000 workers. Among the materials used in the shoe manufacturing process, that could be occupational hazards, are the adhesives, especially adhesives solutions based on organic solvents. The National Institute of Health (Oporto Branch) carried out a study of 100 factories in northern Portugal to study solvent exposure in shoe manufacturing. The surveyed population, (4615 workers) was young (mean age = 33 years; range = 18-45) and predominantly female (68.5%). The results from the air samples analyses show 20 different organic compounds existing in the workplaces. The more common compounds found were n-hexane, toluene, and acetone. The results of the study show that in 53.7 percent of the factories there are operations where the solvent exposure is significant and represents a health hazard to the workers. These operations are mainly gluing, waxing, and polishing stations. Occupational risk of exposure to solvents concerned 44.2 percent of the workers. This study points out the existence of inadequate ventilation in the workplaces and inappropriate personal protective equipment to prevent dermatitis risk from adhesives, wax, and polish. The organic solvents present in workplaces also increase fire risk. 相似文献
68.
The diterpenes ent-kaur-16-en-19-oic acid, ent-kaur-9(11),16(17)-dien-19-oic acid and 3 alpha-angeloiloxy-ent-kaur-16-en-19-oic acid were identified as trypanosomicidal compounds of the ethanolic extract from the aerial parts of Wedelia paludosa D.C. (Asteraceae), showing activity up to the lowest dose of 0.68 mg/mL in the in vitro assay against trypomastigotes of T. cruzi, the causative agent of Chagas' disease (American trypanosomiasis). The other isolates, friedelan-3 beta-ol, ent-kaur-16 alpha-ol-19-oic acid, beta-amyrin acetate and (22-E)-stigmasta-5,22-dien-3 beta-ol, were inactive. This is the first report on the trypanosomicidal activity of ent-kaur-9(11),16(17)-dien-19-oic acid and 3 alpha-angeloiloxy-ent-kaur-16-en-19-oic acids; this effect was already known for ent-kaur-16-en-19-oic acid. 相似文献
69.
Pharmacological evaluation of ricinine, a central nervous system stimulant isolated from Ricinus communis. 总被引:2,自引:0,他引:2
A C Ferraz M E Angelucci M L Da Costa I R Batista B H De Oliveira C Da Cunha 《Pharmacology, biochemistry, and behavior》1999,63(3):367-375
The extract of the pericarp of castor bean (Ricinus communis) showed some typical central nervous system stimulant effects when administered to mice. The animals became exophthalmic, presented tremors and clonic seizures and died a few minutes after receiving larger doses of the extract. At lower doses the extract improved memory consolidation and showed some neuroleptic-like properties, such as a decrease in exploratory behavior and catalepsy. The memory-improving effect and the seizure-eliciting properties of the extract were also observed with the administration of ricinine, a neutral alkaloid isolated from the extract. However, the neuroleptic-like properties of the extract were not observed with ricinine. As the therapeutic index of ricinine is of the order of 200, the compound may be considered as a promising cognition-enhancing drug that may be used for the treatment of human amnesias. 相似文献
70.
Oliva ML Andrade SA Batista IF Sampaio MU Juliano M Fritz H Auerswald EA Sampaio CA 《Immunopharmacology》1999,45(1-3):145-149
Kunitz type Bauhinia ungulata factor Xa inhibitor (BuXI) was purified from B. ungulata seeds. BuXI inactivates factor Xa and human plasma kallikrein (HuPK) with Ki values of 18.4 and 6.9 nM, respectively. However, Bauhinia variegata trypsin inhibitor (BvTI) which is 70% homologous to BuXI does not inhibit factor Xa and is less efficient on HuPK (Ki = 80 nM). The comparison between BuXI and BvTI reactive site structure indicates differences at Met59, Thr66 and Met67 residues. The hydrolysis rate of quenched fluorescence peptide substrates based on BuXI reactive site sequence, Abz-VMIAALPRTMFIQ-EDDnp (leading peptide), by HuPK and porcine pancreatic kallikrein (PoPK) is low, but hydrolysis is enhanced with Abz-VMIAALPRTMQ-EDDnp, derived from the leading peptide shortened by removing the dipeptide Phe-Ileu from the C-terminal portion, for HuPK (Km = 0.68 microM, k(cat)/Km = 1.3 x 10(6) M(-1) s(-1)), and the shorter substrate Abz-LPRTMQ-EDDnp is better for PoPK (Km = 0.66 microM, k(cat)/Km = 2.2 x 10(3) M(-1) s(-1)). The contribution of substrate methionine residues to HuPK and PoPK hydrolysis differs from that observed with factor Xa. The determined Km and k(cat) values suggest that the substrates interact with kallikreins the same as an enzyme and inhibitor interacts to form complexes. 相似文献