全文获取类型
收费全文 | 37283篇 |
免费 | 1725篇 |
国内免费 | 266篇 |
专业分类
耳鼻咽喉 | 242篇 |
儿科学 | 760篇 |
妇产科学 | 344篇 |
基础医学 | 4583篇 |
口腔科学 | 712篇 |
临床医学 | 2305篇 |
内科学 | 9578篇 |
皮肤病学 | 1425篇 |
神经病学 | 2998篇 |
特种医学 | 1526篇 |
外科学 | 6418篇 |
综合类 | 181篇 |
预防医学 | 918篇 |
眼科学 | 434篇 |
药学 | 2783篇 |
中国医学 | 73篇 |
肿瘤学 | 3994篇 |
出版年
2023年 | 229篇 |
2022年 | 435篇 |
2021年 | 800篇 |
2020年 | 418篇 |
2019年 | 620篇 |
2018年 | 798篇 |
2017年 | 619篇 |
2016年 | 828篇 |
2015年 | 848篇 |
2014年 | 1153篇 |
2013年 | 1294篇 |
2012年 | 2050篇 |
2011年 | 2250篇 |
2010年 | 1263篇 |
2009年 | 1061篇 |
2008年 | 1940篇 |
2007年 | 2158篇 |
2006年 | 2137篇 |
2005年 | 2111篇 |
2004年 | 2106篇 |
2003年 | 2038篇 |
2002年 | 1983篇 |
2001年 | 808篇 |
2000年 | 813篇 |
1999年 | 825篇 |
1998年 | 547篇 |
1997年 | 410篇 |
1996年 | 392篇 |
1995年 | 328篇 |
1994年 | 295篇 |
1993年 | 265篇 |
1992年 | 552篇 |
1991年 | 487篇 |
1990年 | 484篇 |
1989年 | 488篇 |
1988年 | 459篇 |
1987年 | 402篇 |
1986年 | 353篇 |
1985年 | 317篇 |
1984年 | 205篇 |
1983年 | 176篇 |
1982年 | 115篇 |
1981年 | 96篇 |
1979年 | 172篇 |
1978年 | 95篇 |
1977年 | 97篇 |
1975年 | 77篇 |
1974年 | 79篇 |
1973年 | 88篇 |
1972年 | 91篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
Akira Sawaki Nobumasa Mizuno Kuniyuki Takahashi Tsuneya Nakamura Masahiro Tajika Hiroki Kawai Toshifumi Isaka Hiroshi Imaoka Yasuyuki Okamoto Masatoshi Aoki Hiroyuki Inoue Ahmed AS Salem Yasushi Yatabe Kenji Yamao 《Digestive endoscopy》2006,18(1):40-44
Background: Gastrointestinal stromal tumors (GIST) are one of the most common mesenchymal tumors of the gastrointestinal tract. GIST are defined by positive immunohistochemical staining for KIT or CD34 and thus are generally diagnosed after surgery. Because small GIST are rarely diagnosed before surgery, the clinical course of these small tumors is not clear. The aim of the present study was to follow changes in size and configuration of small GIST that were pathologically confirmed using endoscopic ultrasonography‐guided fine‐needle aspiration biopsy (EUS‐FNAB). Methods: Between July 1997 and December 2003, 16 tumors in 16 patients (10 men and 6 women) with an immunohistochemical diagnosis of GIST were regularly followed in our hospital. The median patient age when EUS‐FNAB was performed was 62 years (range 26–82 years) and the median follow‐up period was 4.9 years (range 0.5–9.6 years). Results: Fourteen tumors showed no remarkable changes in size and shape during follow up compared with the initial diagnosis. Two tumors enlarged: one tumor approximately doubled its diameter in 8 years and the other tumor increased from 1.8 cm at diagnosis to up to 10 cm after only 2 years. Doubling time of the latter tumor was calculated as 3.1 months. Conclusions: We conclude that EUS‐FNAB might be a good modality for final diagnosis of GIST without surgery, and that GIST without rapid growth on follow up can be endoscopically followed. 相似文献
3.
Relapse of colon cancer followed by polymyositis: Report of a case and review of the literature 总被引:1,自引:0,他引:1
Seietsu Nyui Hiroyuki Osanai Shigeri Ohba Hideji Masuoka Yukinari Yoshida 《Surgery today》1997,27(6):559-562
The direct causal relationship between dermatomyositis-polymyositis (PM) and malignancy remains controversial. We describe
herein the case of a patient who underwent surgical treatment for colon cancer, which had preceded the onset of PM with tumor
relapse. The PM markedly improved following the initiation of steroid therapy, and has remained under control, probably as
a result of chemotherapy. The current concepts of variable clinical courses and the possible mechanism for the association
of PM with malignancy are discussed following this case report. 相似文献
4.
5.
M Yoshino Y Sakaguchi N Kuriya Y Ohtani F Yamashita T Hashimoto K Oyanagi K Tada K Narisawa T Kitagawa 《Neuropediatrics》1991,22(4):198-202
A nationwide survey of transient hyperammonemia in newborns was carried out in Japan. A total of 18 patients, consisting of 12 male and 6 female infants, were reported from 11 facilities. These neonates exhibited hyperammonemia with plasma ammonia levels in the range from 124 to 6256 micrograms/dl. Four newborn infants of the 18 died in the neonatal period, and an additional one died in the early infancy. Among the 13 infants who were alive at the time of this survey, 6 had neurological sequelae, including mental retardation, spastic quadriplegia and epilepsy. The multivariate analysis revealed that the Apgar score at 1 minute, peak plasma ammonia concentration, birth weight and sex were significant factors affecting the prognosis of life. 相似文献
6.
7.
8.
S Watanabe K Nakano H Misumi M Yoshikai M Endo A Hashimoto H Koyanagi 《Nihon Geka Gakkai zasshi》1989,90(9):1513-1516
St. Jude Medical valve replacement was performed in 1,039 patients; 320 had aortic (AVR), 543 mitral (MVR), and 176 had double valve replacement (DVR). There were 44(4.2%) early deaths. Follow-up extended in 995 patients from 10 to 130 months, with a cumulative period of 2,730 patients-years. The overall survival rates of AVR, MVR, and DVR patients at 10 years were 60.5%, 89.6%, 90.3% respectively. The linearized incidences of valve thrombosis, thromboembolism, anticoagulation-related hemorrhage, prosthetic valve endocarditis, and significant hemolysis were as follows: 0.11%/pt-yr, 1.33%/pt-yr, 0.04%/pt-yr, 0.18%/pt-yr, and 0.11%/pt-yr, respectively. There were no structural failure after 10 years follow-up. Reoperation (explant and re-replacement or suture repair) was required in 10 patients. Seven of them had periprosthetic leakage, 2 had valve thrombosis, and one underwent reoperation because of a technical error. Actuarially over 98% of patients were free of valve-related mortality at 10 years. St. Jude Medical valve is an excellent alternative for use in the surgical treatment of valvular heart disease. 相似文献
9.
10.