全文获取类型
收费全文 | 3953篇 |
免费 | 192篇 |
国内免费 | 26篇 |
专业分类
耳鼻咽喉 | 57篇 |
儿科学 | 70篇 |
妇产科学 | 43篇 |
基础医学 | 524篇 |
口腔科学 | 460篇 |
临床医学 | 272篇 |
内科学 | 779篇 |
皮肤病学 | 114篇 |
神经病学 | 329篇 |
特种医学 | 71篇 |
外科学 | 488篇 |
综合类 | 16篇 |
预防医学 | 450篇 |
眼科学 | 41篇 |
药学 | 199篇 |
中国医学 | 36篇 |
肿瘤学 | 222篇 |
出版年
2023年 | 43篇 |
2022年 | 75篇 |
2021年 | 149篇 |
2020年 | 83篇 |
2019年 | 113篇 |
2018年 | 160篇 |
2017年 | 91篇 |
2016年 | 100篇 |
2015年 | 134篇 |
2014年 | 192篇 |
2013年 | 237篇 |
2012年 | 315篇 |
2011年 | 369篇 |
2010年 | 172篇 |
2009年 | 149篇 |
2008年 | 229篇 |
2007年 | 207篇 |
2006年 | 221篇 |
2005年 | 167篇 |
2004年 | 194篇 |
2003年 | 125篇 |
2002年 | 98篇 |
2001年 | 71篇 |
2000年 | 66篇 |
1999年 | 58篇 |
1998年 | 30篇 |
1997年 | 16篇 |
1996年 | 15篇 |
1995年 | 20篇 |
1994年 | 9篇 |
1993年 | 8篇 |
1992年 | 32篇 |
1991年 | 31篇 |
1990年 | 24篇 |
1989年 | 27篇 |
1988年 | 17篇 |
1987年 | 11篇 |
1986年 | 10篇 |
1985年 | 12篇 |
1984年 | 7篇 |
1983年 | 11篇 |
1982年 | 4篇 |
1981年 | 4篇 |
1973年 | 6篇 |
1972年 | 5篇 |
1971年 | 4篇 |
1970年 | 7篇 |
1969年 | 6篇 |
1968年 | 4篇 |
1965年 | 3篇 |
排序方式: 共有4171条查询结果,搜索用时 15 毫秒
1.
Milena Soares Santos Guilherme de Sousa Ribeiro Tainara Queiroz Oliveira Renan Cardoso Nery Santos Edilane Gouveia Kátia Salgado Daniele Takahashi Cleuber Fontes Leila Carvalho Campos Mitermayer Galvão Reis Albert Icksang Ko Joice Neves Reis 《International journal of infectious diseases》2009,13(4):456-461
2.
Nuno Fonseca Filomena Caetano José Santos Filipe Seixo Leonel Bernardino Isabel Silvestre Paula Cardoso Filomena Segurado Lopes Inês 《Revista portuguesa de cardiologia》2004,23(3):365-375
INTRODUCTION: In patients (pts) with atrial fibrillation (AF) of more than 48 hours' duration, electrical cardioversion (ECV) should only be performed after 3 weeks of effective anticoagulation. Transesophageal echocardiography (TEE) allows earlier ECV; however, despite exclusion of thrombi in the atrium and left atrial appendage (LAA), cases of thromboembolism related to ECV have been documented in AF. To define a low-risk group for cardioversion without previous anticoagulation, pts were selected for immediate ECV if no thrombi or dynamic spontaneous echo contrast (auto-contrast) were found after TEE and if LAA velocity was more than 0.25 m/sec. METHODS AND RESULTS: We performed TEE in 31 consecutive pts referred for ECV for AF of more than 48 hours' duration and without previous anticoagulation. After TEE the pts eligible for immediate ECV began anticoagulation with low molecular weight heparin (enoxaparin), subcutaneously in therapeutic doses, together with warfarin immediately before cardioversion. Enoxaparin was continued until an INR of over 2 was reached. Based on the TEE findings, the pts were divided in 2 groups: immediate ECV, group A, 20 pts with a mean age of 62 +/- 13 years, 6 female; and conventional therapy with warfarin before ECV, group B, 11 pts, mean age of 67 +/- 10 years (p < 0.05), 2 female. None of the pts in either group had mitral stenosis or previous episodes of thromboembolism. The mean transverse diameter of the left atrium in the 31 pts was 47 +/- 4.5 mm, without statistically significant differences between the 2 groups. Of the 11 pts in group B, 3 had a thrombus in the LAA, 6 dynamic spontaneous echo contrast and the remainder LAA velocities of less than 0.25 m/sec. ECV was achieved in all the pts, with no complications. Oral anticoagulation was maintained for at least a month. At one month, sinus rhythm was maintained in 75% of group A and 45% of group B (p < 0.01). CONCLUSION: In pts with AF of more than 48 hours' duration and no previous history of thromboembolism, the use of our exclusion criteria during TEE enabled stratification of a low-risk population for immediate ECV, which was accomplished effectively and safely in 2/3 of the pts. This strategy is associated with early symptomatic improvement, and may contribute to maintenance of sinus rhythm after one month, which was significantly better than in the pts who had prolonged therapy with warfarin before ECV, despite the differences found in age and left ventricular function. 相似文献
3.
We report a case of mammaplasty followed by a marked convergence of the nipple-areolar complex and describe the surgical repair by means of an inferior dermal-fat curved flap. The curve of the inferior pedicle permits one to raise the nipple to its normal position with ease and exceptional viability, even if a breast reduction procedure is associated. 相似文献
4.
Loxosceles gaucho spider venom causes a typical dermonecrotic lesion in bitten patients and rarely causes lethal systemic effects. Gel filtration on Sephadex G 100 of L. gaucho spider venom resulted in three fractions: fraction A, containing the higher mol. wt components (approximately 35,000); fraction B, containing lower mol. wt components (approximately 15,000); and fraction C, containing very low mol. wt components (probably small peptides). The dermonecrotic and lethal activities were detected exclusively in fraction A. The venom and fraction A produced large dermonecrotic lesions in rabbits with necrosis spreading by gravity to the skin of the lateral body wall. Analysis by SDS-PAGE showed that the proteins contained in fraction A are approximately 35,000 and 33,000 mol. wt. Immunoblotting analysis showed that the proteins responsible for the dermonecrotic and lethal activity are very immunogenic and the first to be detected by antibodies during the course of immunization. 相似文献
5.
6.
7.
8.
9.
Gribova A Donchin O Bergman H Vaadia E Cardoso De Oliveira S 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2002,144(3):322-335
It has been established that repeated presentation of a transient target motion stimulus such as a constant-velocity ramp leads to the build up of steady state (SS), anticipatory smooth pursuit eye movements after two or three presentations. Each SS response is then composed of the anticipatory component of nonvisual origin, a visual component associated with the stimulus presentation and another nonvisual component that represents the decay of the response after extinction of the stimulus. Here we investigated the interactions that occur when each motion stimulus was itself a sequence containing more than one ramp component. Ramp components had a velocity of 15 degrees /s or 30 degrees /s to left or right and were separated by gaps of 200 ms duration. In an initial experiment, responses to 2-ramp stimuli were examined and compared with responses to the single-ramp stimuli from which they were constituted. We present evidence that the anticipatory, nonvisual components of the double-ramp response result from the linear summation of the nonvisual components of the responses to the constituent single-ramp components. In a 2nd experiment, we examined responses to a wide variety of 4-ramp sequences and again found evidence that, in the SS, the responses were formed from the linear summation of the constituent single-ramp components. Regression analysis performed on the velocity at onset of each ramp component indicated that this nonvisual part of the response was predictive of the upcoming ramp component. To confirm this, unexpected changes were introduced into single ramp components of the 4-ramp sequence after at least five prior presentations of the sequence had allowed a SS response to be established. Subjects continued to initiate a response to the modified component that was appropriate in velocity and direction for the corresponding part of the previous sequence and inappropriate for the newly modified stimulus. This preprogrammed response persisted unmodified for more than 170 ms after onset of the modified ramp component. In contrast, in the second presentation of the new sequence, the anticipatory component of the response was highly correlated with the SS response of the new sequence, but not with that of the prior sequence, showing that the preprogrammed response had been modified very rapidly. Similar behaviour was observed whichever of the 4-ramp components was modified, indicating that the velocity and direction of the anticipatory response to each component had been preprogrammed. The results suggest that velocity information related to at least four elements of a sequence can be temporarily stored and subsequently released with appropriate temporal order to form an anticipatory response throughout the whole sequence. 相似文献
10.
V Júnior Haddad H A Miot L D Bartoli A de Chiara Cardoso R M Pires de Camargo 《Medical mycology》2002,40(4):425-427
Localized lymphatic sporotrichosis generally develops after the fungus Sporothrix schenckii is traumatically introduced into skin or mucosa by contaminated plant material. An 18-year-old male fisherman was injured by spines of the dorsal fin of a fish on the left third finger. The lesion became ulcerated, edematous and suppurative and did not respond to tetracycline and cephalexin. Fifteen days after the accident, a nodular lymphangitic pattern of swelling was observed. Histopathological findings and an intradermal test were suggestive of sporotrichosis and mycological cultures confirmed the diagnosis. The lesions resolved after oral treatment with potassium iodide. Sporotrichosis is a common subcutaneous mycosis in Brazil, and there is a previous report in the literature of this disease being acquired via trauma involving fish spines. 相似文献