全文获取类型
收费全文 | 25400篇 |
免费 | 1234篇 |
国内免费 | 240篇 |
专业分类
耳鼻咽喉 | 231篇 |
儿科学 | 463篇 |
妇产科学 | 268篇 |
基础医学 | 2921篇 |
口腔科学 | 563篇 |
临床医学 | 1649篇 |
内科学 | 7489篇 |
皮肤病学 | 505篇 |
神经病学 | 1906篇 |
特种医学 | 841篇 |
外科学 | 4379篇 |
综合类 | 120篇 |
一般理论 | 4篇 |
预防医学 | 647篇 |
眼科学 | 688篇 |
药学 | 1562篇 |
中国医学 | 62篇 |
肿瘤学 | 2576篇 |
出版年
2023年 | 210篇 |
2022年 | 389篇 |
2021年 | 686篇 |
2020年 | 378篇 |
2019年 | 513篇 |
2018年 | 570篇 |
2017年 | 465篇 |
2016年 | 581篇 |
2015年 | 597篇 |
2014年 | 766篇 |
2013年 | 889篇 |
2012年 | 1549篇 |
2011年 | 1726篇 |
2010年 | 1040篇 |
2009年 | 782篇 |
2008年 | 1333篇 |
2007年 | 1543篇 |
2006年 | 1461篇 |
2005年 | 1446篇 |
2004年 | 1344篇 |
2003年 | 1264篇 |
2002年 | 1286篇 |
2001年 | 528篇 |
2000年 | 446篇 |
1999年 | 469篇 |
1998年 | 302篇 |
1997年 | 263篇 |
1996年 | 241篇 |
1995年 | 185篇 |
1994年 | 159篇 |
1993年 | 172篇 |
1992年 | 331篇 |
1991年 | 256篇 |
1990年 | 231篇 |
1989年 | 262篇 |
1988年 | 204篇 |
1987年 | 242篇 |
1986年 | 199篇 |
1985年 | 196篇 |
1984年 | 151篇 |
1983年 | 120篇 |
1982年 | 60篇 |
1979年 | 124篇 |
1978年 | 59篇 |
1975年 | 60篇 |
1974年 | 72篇 |
1972年 | 58篇 |
1970年 | 73篇 |
1968年 | 67篇 |
1967年 | 61篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Yosuke Homma Takashi Shiga Hiraku Funakoshi Dai Miyazaki Atsushi Sakurai Yoshio Tahara Ken Nagao Naohiro Yonemoto Arino Yaguchi Naoto Morimura 《The American journal of emergency medicine》2019,37(2):241-248
Objective
This study assessed the association between the timing of first epinephrine administration (EA) and the neurological outcomes following out-of-hospital cardiac arrests (OHCAs) with both initial shockable and non-shockable rhythms.Methods
This was a post-hoc analysis of a multicenter prospective cohort study (SOS-KANTO 2012), which registered OHCA patients in the Kanto region of Japan from January 2012 to March 2013. We included consecutive adult OHCA patients who received epinephrine. The primary result included 1-month favorable neurological outcomes defined as cerebral performance category (CPC) 1 or 2. Secondary results included 1-month survival and return of spontaneous circulation (ROSC) after arrival at the hospital. Multivariable logistic regression analysis determined the association between delay per minute of the time from call to first EA in both pre- or in-hospital settings and outcomes.Results
Of the 16,452 patients, 9344 were eligible for our analyses. In univariable analysis, the delay in EA was associated with decreased favorable neurological outcomes only when the initial rhythm was a non-shockable rhythm. In multivariable analyses, delay in EA was associated with decreased ROSC (adjusted odds ratio [OR] for one minute delay, 0.97; 95% confidence interval [CI], 0.96–0.98) and 1-month survival (adjusted OR, 0.95; 95% CI, 0.92–0.97) when the initial rhythm was a non-shockable rhythm, whereas during a shockable rhythm, delay in EA was not associated with decreased ROSC and 1-month survival.Conclusions
While assessing the effectiveness of epinephrine for OHCA, we should consider the time-limited effects of epinephrine. Additionally, consideration of early EA based on the pathophysiology is needed. 相似文献2.
Takao Itoi Atsushi Sofuni Fumihide Itokawa Yasushi Shinohara Kazuya Takeda Kazuto Nakamura Toshio Kurihara Takayoshi Tsuchiya Fuminori Moriyasu 《Digestive endoscopy》2006,18(3):232-238
We describe our methods and outcomes of multidisciplinary treatments in patients with unresectable hilar cholangiocarcinoma. Fifty‐seven patients with a known outcome were enrolled. Thirty‐four of 57 patients were treated and evaluated by salvage therapy. For salvage therapy, we used internal and external radiotherapy, photodynamic therapy, YAG laser therapy and microwave coagulation therapy. The median survival time was 548 days for the group receiving salvage therapy and 198 days for the group not receiving this treatment. In conclusion, although no randomization of the patients was performed in this retrospective study, our present data provide convincing evidence that salvage therapy is a useful therapeutic approach for unresectable hilar cholangiocarcinomas. 相似文献
3.
4.
5.
A case of Ullrich disease was presented. The patient was a 3-year-old girl with torticollis, generalized muscle weakness and acroatonia since birth. High-arched palate, protruded calcaneus, and mild contracture of proximal joints were also recognized. Intellectual development was normal. Serum level of CPK was slightly increased. In histological and histochemical examinations of quadriceps femoris muscle, proliferated connective tissue, marked variation in the muscle fiber diameter, and a lot of degenerated and regenerated fibers were recognized. Minimal injury easily causes subcutaneous hemorrhage, but no abnormality was found in the structure of collagen. 相似文献
6.
7.
8.
Madoka Minoguchi Nobuyuki Yanagawa Chisato Ishikawa Junpei Sasajima Mitsuru Goto Miho Okamoto Yoshinori Saito Masanori Murakami Yutaka Orii Toru Yaosaka 《Nihon Shokakibyo Gakkai zasshi》2007,104(7):1082-1087
Pancreatic metastasis of malignant melanoma is rarely diagnosed while the patient is alive. We report a case of metastatic melanoma of the pancreas in a 35-year-old woman presenting with a solid mass of the pancreas. Her past medical history included a radical hysterectomy 2 years previously for malignant melanoma of the vagina. Twelve months later, lung metastasis was also resected. EUS-guided fine needle aspiration (EUS-FNA) identified that the pancreatic tumor was histologically and immunohistochemically identical to the surgical specimen of her lung neoplasm. Imaging studies including US, CT, and MRI have limited value to distinguish the tumors from primary ductal adenocarcinoma. EUS-FNA can provide tissue diagnosis from pancreatic masses, specifically when other modalities have failed. 相似文献
9.
10.