全文获取类型
收费全文 | 73826篇 |
免费 | 7024篇 |
国内免费 | 4177篇 |
专业分类
耳鼻咽喉 | 770篇 |
儿科学 | 1289篇 |
妇产科学 | 779篇 |
基础医学 | 7307篇 |
口腔科学 | 1461篇 |
临床医学 | 9529篇 |
内科学 | 10050篇 |
皮肤病学 | 1474篇 |
神经病学 | 2837篇 |
特种医学 | 3184篇 |
外国民族医学 | 22篇 |
外科学 | 6441篇 |
综合类 | 13700篇 |
现状与发展 | 17篇 |
一般理论 | 4篇 |
预防医学 | 6658篇 |
眼科学 | 1560篇 |
药学 | 8430篇 |
80篇 | |
中国医学 | 4806篇 |
肿瘤学 | 4629篇 |
出版年
2024年 | 247篇 |
2023年 | 1011篇 |
2022年 | 2533篇 |
2021年 | 3459篇 |
2020年 | 2670篇 |
2019年 | 2162篇 |
2018年 | 2211篇 |
2017年 | 2337篇 |
2016年 | 2207篇 |
2015年 | 3533篇 |
2014年 | 4485篇 |
2013年 | 4772篇 |
2012年 | 6840篇 |
2011年 | 7006篇 |
2010年 | 5235篇 |
2009年 | 4387篇 |
2008年 | 4931篇 |
2007年 | 4580篇 |
2006年 | 4383篇 |
2005年 | 3674篇 |
2004年 | 2613篇 |
2003年 | 2264篇 |
2002年 | 1907篇 |
2001年 | 1218篇 |
2000年 | 969篇 |
1999年 | 717篇 |
1998年 | 385篇 |
1997年 | 444篇 |
1996年 | 300篇 |
1995年 | 270篇 |
1994年 | 242篇 |
1993年 | 150篇 |
1992年 | 150篇 |
1991年 | 145篇 |
1990年 | 102篇 |
1989年 | 82篇 |
1988年 | 74篇 |
1987年 | 54篇 |
1986年 | 45篇 |
1985年 | 34篇 |
1984年 | 30篇 |
1983年 | 22篇 |
1982年 | 14篇 |
1981年 | 20篇 |
1980年 | 16篇 |
1979年 | 11篇 |
1978年 | 10篇 |
1975年 | 7篇 |
1974年 | 7篇 |
1972年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
药物依赖心理治疗的基本技术——动机强化治疗的理论与技术 总被引:3,自引:1,他引:2
赵敏 《中国药物滥用防治杂志》2006,12(6):311-314
现代科学证实,药物依赖(吸毒)是一种慢性复发性脑疾病,具有复杂的心理学、生物学与社会学病因机制,应采取躯体、心理、社会康复等综合治疗的模式来治疗药物依赖导致的各种相关问题,对药物依赖的治疗过程是一个长期的、复杂的过程。脱毒只是戒毒治疗的前提,除海洛因等阿片类药物 相似文献
2.
Vincent Chung Liang Liu Zhaoxiang Bian Zhongzhen Zhao Wai Leuk Fong Wan Fung Kum Jing Gao Min Li 《Movement disorders》2006,21(10):1709-1715
The objective of this study is to assess the efficacy and safety of herbal medicines (HMs), as a monotherapy or adjunct therapy, compared to placebo or conventional approaches in the treatment of idiopathic Parkinson's disease (PD). We conducted a systematic review of randomized controlled trials from both conventional and alternative medicine sources. Outcome measures were overall improvement, quality of life, reduction of levodopa dose, and adverse events. Nine studies were included, each testing a different HM. Six of the trials had limited internal validity due to major flaws in design, including the lack of proper randomization; insufficient blinding; unclear inclusive criteria in terms of diagnostic criteria, baseline staging, and duration of disease; lack of proper sample size calculation; and insufficient data analysis. Imbalances in gender and ethnicity among the patients in the included trials were observed. No major adverse events emerged, and no specific pattern was detected from the trials describing such data. In addition to major methodological defects, heterogeneity in (1) HM tested, (2) control treatment, and (3) outcome measure hindered in-depth data analysis and synthesis. Current evidence is insufficient to evaluate the efficacy and safety of various HMs. Further studies with improved trial design and reporting, with assessment on cost-effectiveness, quality of life, and qualitative data are warranted. 相似文献
3.
4.
5.
抽动障碍中医证型与血清单胺类物质的相关性研究 总被引:1,自引:0,他引:1
目的 观察抽动障碍不同中医证型患者血清多巴胺、去甲肾上腺素等单胺类神经递质的水平,并探讨各证型之间血清神经递质的水平是否存在差别.方法 采用化学荧光法测定46例抽动障碍患者(病例组)血清多巴胺、去甲肾上腺素水平,并与40例正常儿童(对照组)进行比较.结果 病例组血清多巴胺为0.449μg/ml,对照组为0.210μg/ml;病例组血清去甲肾上腺素为0.227μg/ml,对照组为0.127μg/ml,两组各均值比较,病例组血清多巴胺和去甲肾上腺素均显著高于对照组.病例组外风侵袭、肝风内动型,或兼气郁化火型,或兼脾虚痰聚型,或兼阴虚风动型血清多巴胺水平分别为0.316、0.400、0.235、0.247μg/ml,四者比较有显著性差异;病例组符证型血清去甲.肾上腺素水平分别为0.203、0.224、0.144、0.154μg/ml,四者比较差异有显著性.结论 抽动障碍患者存在多巴胺和去甲肾上腺素水平异常,且各证型血清多巴胺、去甲肾上腺素水平有明显差异,而尤其以外风侵袭、肝风内动兼气郁化火型水平最高. 相似文献
6.
Man Bok Jeong Kristina Narfström Shin Ae Park Je Min Chae Kang Moon Seo 《Documenta ophthalmologica. Advances in ophthalmology》2009,119(2):79-88
The objective of this study is to compare the effects of three different anesthetic combinations on the electroretinogram
in the same animals under similar laboratory conditions. Thiopental–isoflurane (TI), medetomidine–ketamine (MK), and xylazine–ketamine
(XK) were used on each of 12 healthy miniature schnauzer dogs (MS) with a period of at least 3 weeks in between subsequent
anesthesia protocols, using the Dog Standard Protocol. The scotopic ERGs consisted of scotopic low stimulus strength (S) responses
designated S1, S2, S3, S4, and S5, at 1, 5, 10, 15, and 20 min after dark adaptation, respectively, and scotopic standard
stimulus strength (S-ST) responses. The photopic ERGs consisted of a photopic single flash (P) response and 31 Hz flicker
(P-FL) responses. For S-ST (2.5 cd s/m2), the amplitude of the a-wave using TI was significantly lower than that using MK (adjusted P = 0.05) and XK (adjusted P = 0.03), and the implicit time of the a-wave was significantly shorter than that using MK (adjusted P = 0.04). For P (2.5 cd s/m2), the amplitude of the b-wave using XK was significantly higher than that using MK (adjusted P = 0.01). The implicit times of the b-wave using TI was significantly longer and shorter than that of MK for S1, S2 and P-FL
and for S4 and S-ST, respectively, and than that of XK for S2 and P-FL and for S5 and S-ST, respectively. The results of the
present study showed that TI affected both the amplitude and the implicit time of the a-wave for S-ST and the implicit time
of the b-wave relatively more so than was the case when using XK or MK. Therefore, it appears that either XK or MK could be
advantageous to use rather than TI for clinical studies. 相似文献
7.
8.
通过对 5 0 0例经尿 11项试纸检查阴性的标本 ,沉渣镜检发现尚有 6 7例阳性 ,阳性率为 13.4 %。提示尿沉渣镜检 ,不失为泌尿系统疾病检查的必要手段不应忽视及偏废 相似文献
9.
抑郁症患者心理治疗的临床研究 总被引:2,自引:1,他引:1
目的 通过对照的方法,对抑郁症患者使用单纯抗抑郁药物治疗和药物合并心理治疗的疗效进行比较,探讨心理治疗在抑郁症患者治疗中的作用.方法 选取抑郁症患者120例,随机分成两组.对照组60例,男女各半,年龄18~65岁,平均(38.9±2.53)岁;心理治疗组60例,男女各半,年龄19~67岁,平均(39.7±3.12)岁.两组患者均给予帕罗西汀(商品名赛乐特)20mg/d,对照组单纯用药物治疗,心理治疗组药物加心理治疗,疗程8周.分别于第0周(基线)、干预后第2周、第4周、第8周使用汉密顿抑郁量表(HAMD)和抑郁自评量表(SDS)进行评分.结果 药物合并心理治疗组的治疗效果优于对照组(P<0.05),且治疗时间越长,两组的疗效差异越明显.结论 心理治疗对抑郁症患者的康复有积极的作用,药物治疗合并心理治疗较单纯药物治疗更有利. 相似文献
10.
Amrik Sahota Min Yang Sujuan Gao Siu L. Hui Olusegun Baiyewu Oyewusi Gureje Steven Oluwole Adesola Ogunniyi Kathleen S. Hall Hugh C. Hendrie 《Annals of neurology》1997,42(4):659-661
As a part of our ongoing study on Alzheimer's disease (AD) in elderly African Americans, we obtained clinical assessment and apolipoprotein E (ApoE) genotype data on 288 individuals (including 60 with AD). The ApoE σ4 allele frequency was significantly increased in AD patients compared with controls. The age-adjusted odds ratio (OR) for AD in σ4 homozygotes was 4.83 (95% confidence interval [CI], 1.71–13.64) compared with the σ3/σ3 genotype, but the OR for AD with the σ3/σ4 genotype did not reach significance (1.20; 95% CI, 0.58–2.45). These findings suggest that the association between ApoE σ4 and AD is weaker in African Americans than in whites. 相似文献