全文获取类型
收费全文 | 12391篇 |
免费 | 1353篇 |
国内免费 | 20篇 |
专业分类
耳鼻咽喉 | 91篇 |
儿科学 | 458篇 |
妇产科学 | 315篇 |
基础医学 | 1906篇 |
口腔科学 | 202篇 |
临床医学 | 1340篇 |
内科学 | 2510篇 |
皮肤病学 | 139篇 |
神经病学 | 1045篇 |
特种医学 | 319篇 |
外科学 | 1426篇 |
综合类 | 270篇 |
一般理论 | 14篇 |
预防医学 | 1492篇 |
眼科学 | 173篇 |
药学 | 1073篇 |
中国医学 | 23篇 |
肿瘤学 | 968篇 |
出版年
2021年 | 175篇 |
2020年 | 125篇 |
2019年 | 142篇 |
2018年 | 222篇 |
2017年 | 151篇 |
2016年 | 207篇 |
2015年 | 205篇 |
2014年 | 307篇 |
2013年 | 496篇 |
2012年 | 658篇 |
2011年 | 707篇 |
2010年 | 359篇 |
2009年 | 374篇 |
2008年 | 643篇 |
2007年 | 713篇 |
2006年 | 657篇 |
2005年 | 654篇 |
2004年 | 657篇 |
2003年 | 600篇 |
2002年 | 616篇 |
2001年 | 249篇 |
2000年 | 252篇 |
1999年 | 233篇 |
1998年 | 165篇 |
1997年 | 161篇 |
1996年 | 159篇 |
1995年 | 147篇 |
1994年 | 144篇 |
1993年 | 144篇 |
1992年 | 216篇 |
1991年 | 222篇 |
1990年 | 217篇 |
1989年 | 167篇 |
1988年 | 190篇 |
1987年 | 179篇 |
1986年 | 139篇 |
1985年 | 179篇 |
1984年 | 137篇 |
1983年 | 132篇 |
1982年 | 108篇 |
1981年 | 93篇 |
1980年 | 96篇 |
1979年 | 111篇 |
1978年 | 93篇 |
1977年 | 69篇 |
1976年 | 66篇 |
1975年 | 81篇 |
1974年 | 89篇 |
1973年 | 81篇 |
1972年 | 75篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
Ann S. O’Malley Kevin Draper Rebecca Gourevitch Dori A. Cross Sarah Hudson Scholle 《J Am Med Inform Assoc》2015,22(2):426-434
Objective Consensus that enhanced teamwork is necessary for efficient and effective primary care delivery is growing. We sought to identify how electronic health records (EHRs) facilitate and pose challenges to primary care teams as well as how practices are overcoming these challenges.Methods Practices in this qualitative study were selected from those recognized as patient-centered medical homes via the National Committee for Quality Assurance 2011 tool, which included a section on practice teamwork. We interviewed 63 respondents, ranging from physicians to front-desk staff, from 27 primary care practices ranging in size, type, geography, and population size.Results EHRs were found to facilitate communication and task delegation in primary care teams through instant messaging, task management software, and the ability to create evidence-based templates for symptom-specific data collection from patients by medical assistants and nurses (which can offload work from physicians). Areas where respondents felt that electronic medical record EHR functionalities were weakest and posed challenges to teamwork included the lack of integrated care manager software and care plans in EHRs, poor practice registry functionality and interoperability, and inadequate ease of tracking patient data in the EHR over time.Discussion Practices developed solutions for some of the challenges they faced when attempting to use EHRs to support teamwork but wanted more permanent vendor and policy solutions for other challenges.Conclusions EHR vendors in the United States need to work alongside practicing primary care teams to create more clinically useful EHRs that support dynamic care plans, integrated care management software, more functional and interoperable practice registries, and greater ease of data tracking over time. 相似文献
2.
3.
James I. Geller MD Joseph G. Pressey MD Malcolm A. Smith MD Rachel A. Kudgus PhD Mariana Cajaiba MD Joel M. Reid PhD David Hall PhD Donald A. Barkauskas PhD Stephen D. Voss MD Steve Y. Cho MD Stacey L. Berg MD Jeffrey S. Dome MD PhD Elizabeth Fox MD Brenda J. Weigel MD 《Cancer》2020,126(24):5303-5310
4.
5.
6.
7.
8.
Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: a prospective, randomized trial 总被引:1,自引:0,他引:1
M A Hudson T L Ratliff D P Gillen E O Haaff S M Dresner W J Catalona 《The Journal of urology》1987,138(2):295-298
A total of 42 patients with recurrent superficial bladder tumors or carcinoma in situ entered a prospective, randomized trial to compare the efficacy of bacillus Calmette-Guerin therapy with and without quarterly maintenance instillations of bacillus Calmette-Guerin. Maintenance therapy did not reduce further bladder tumor recurrence rates or the interval to recurrence in patients who responded to the initial course of therapy. However, prolongation of toxicity was observed with maintenance bacillus Calmette-Guerin therapy. 相似文献
9.
Angiogenesis induction and regression in human surgical wounds 总被引:2,自引:0,他引:2
Nicola J. Brown PhD ; Edward A. E. Smyth Bmedsci ; Simon S. Cross MD ; Malcolm W. R. Reed MD 《Wound repair and regeneration》2002,10(4):245-251
Angiogenesis in human wound healing is not well characterized, with only sparse information available regarding the maturation and fate of vessels formed as a consequence of human tissue repair. Therefore, this study aimed to establish the temporal profile of angiogenesis in human dermal wounds. Punch biopsies were obtained under local anesthesia from 45 patients following breast surgery. Scars were predominantly between 2 and 52 weeks after surgery but in five patients were > 52 weeks. Control samples were taken from breast skin peroperatively (n = 24). Quantification of vascular density was performed using the Chalkley grid, following antibody staining for platelet endothelial cell adhesion molecule. Vascular patterns, wound cellularity and morphology were also determined. Cumulative microvessel density was increased in all samples when compared to controls (p < 0.05). This was greatest 2 to 24 weeks following surgery 17 (15-21) median (range), decreased thereafter, but remained elevated compared to controls even in the mature scars > 52 weeks. Control tissue showed an ordered morphological arrangement of dermal structures, collagen, and elastic fibers. However, wounding resulted in marked structural distortion for up to 15 weeks. In conclusion, this study shows for the first time the prolonged persistence of both microvessels and cellularity (fibroblastic cells), in addition to structural distortion in human dermal wounds, which is in contrast to previous in vitro and in vivo studies. 相似文献
10.
Michael C. Dalsing MD Melissa Kevorkian BS Beth Raper BA Craig Nixon MS Stephen G. Lalka MD Dolores F. Cikrit MD Joseph L. Unthank PhD Malcolm B. Herring MD 《Annals of vascular surgery》1989,3(2):127-133
This study evaluates the potential for endothelial seeding of a collagen-impregnated Dacron graft with or without surface modifiers (fibronectin, heparin) to attach and retain these cells during flow. Human umbilical endothelial cells were harvested, cultured, labeled with Indium111-oxine and seeded onto 30 mm X 4 mm diameter grafts. Six graft surfaces were studied: 1) a collagen-impregnated Dacron graft, HemashieldR (C); 2) C + fibronectin (C + F); 3) C + heparin (C + H); 4) C + F + H; 5) HytrelR + F (Hyt + F); and 6) Hyt + F + H. Radioactive loss determined the percentage attachment and then percentage retention of labeled inoculum after a one-hour in vitro perfusion. Scanning electron and light microscopy demonstrated the endothelium on the graft surface following perfusion. Fibronectin-coated grafts had a significantly higher percentage attachment than those without fibronectin (ANOVA, P less than 0.05). However, the percentage retention following perfusion was similar for all Dacron grafts and statistically inferior to the HytrelR grafts studied (ANOVA, P less than 0.05). SEM evaluation of the C + F + H graft surface was qualitatively the most impressive Dacron surface for seeding, yet was inferior to the HytrelR graft. We conclude that fibronectin benefits the initial attachment of endothelium to collagen-coated Dacron rivaling the HytrelR surface. Fibronectin does not improve percentage retention of the HemashieldR surface during perfusion, therefore, some of its initial benefit is lost. 相似文献