全文获取类型
收费全文 | 29995篇 |
免费 | 2909篇 |
国内免费 | 2177篇 |
专业分类
耳鼻咽喉 | 222篇 |
儿科学 | 478篇 |
妇产科学 | 374篇 |
基础医学 | 3455篇 |
口腔科学 | 565篇 |
临床医学 | 4048篇 |
内科学 | 4565篇 |
皮肤病学 | 291篇 |
神经病学 | 1463篇 |
特种医学 | 1421篇 |
外国民族医学 | 12篇 |
外科学 | 3374篇 |
综合类 | 4800篇 |
现状与发展 | 6篇 |
一般理论 | 3篇 |
预防医学 | 1923篇 |
眼科学 | 692篇 |
药学 | 3161篇 |
28篇 | |
中国医学 | 1584篇 |
肿瘤学 | 2616篇 |
出版年
2024年 | 71篇 |
2023年 | 386篇 |
2022年 | 828篇 |
2021年 | 1362篇 |
2020年 | 1021篇 |
2019年 | 936篇 |
2018年 | 978篇 |
2017年 | 934篇 |
2016年 | 956篇 |
2015年 | 1337篇 |
2014年 | 1634篇 |
2013年 | 1501篇 |
2012年 | 1956篇 |
2011年 | 2354篇 |
2010年 | 1530篇 |
2009年 | 1221篇 |
2008年 | 1526篇 |
2007年 | 1618篇 |
2006年 | 1530篇 |
2005年 | 1499篇 |
2004年 | 1135篇 |
2003年 | 1154篇 |
2002年 | 1025篇 |
2001年 | 881篇 |
2000年 | 807篇 |
1999年 | 768篇 |
1998年 | 505篇 |
1997年 | 583篇 |
1996年 | 389篇 |
1995年 | 346篇 |
1994年 | 269篇 |
1993年 | 232篇 |
1992年 | 242篇 |
1991年 | 221篇 |
1990年 | 194篇 |
1989年 | 190篇 |
1988年 | 155篇 |
1987年 | 161篇 |
1986年 | 129篇 |
1985年 | 93篇 |
1984年 | 61篇 |
1983年 | 40篇 |
1982年 | 26篇 |
1981年 | 25篇 |
1980年 | 34篇 |
1979年 | 46篇 |
1978年 | 27篇 |
1977年 | 18篇 |
1975年 | 20篇 |
1974年 | 20篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Xiumei Jiang Xiaowei Zhang Patrick Gray Jiwen Zheng Timothy R. Croley Peter P. Fu 《journal of environmental science and health part c-environmental carcinogenesis & ecotoxicology reviews》2019,37(2):116-131
Gold nanoparticles (Au NPs) hold great promise in food, industrial and biomedical applications due to their unique physicochemical properties. However, influences of the gastrointestinal tract (GIT), a likely route for Au NPs administration, on the physicochemical properties of Au NPs has been rarely evaluated. Here, we investigated the influence of GIT fluids on the physicochemical properties of Au NPs (5, 50, and 100?nm) and their implications on intestinal epithelial permeability in vitro. Au NPs aggregated in fasted gastric fluids and generated hydroxyl radicals in the presence of H2O2. Cell studies showed that GIT fluids incubation of Au NPs affected the cellular uptake of Au NPs but did not induce cytotoxicity or disturb the intestinal epithelial permeability. 相似文献
3.
4.
Simeprevir added to peginterferon and ribavirin lessens time with fatigue,depressive symptoms and functional limitations in patients with chronic hepatitis C compared with peginterferon and ribavirin: results from 1161 patients in the QUEST‐1, QUEST‐2 and PROMISE studies
下载免费PDF全文
![点击此处可从《Journal of viral hepatitis》网站下载免费的PDF全文](/ch/ext_images/free.gif)
J. Scott L. Gilles M. Fu E. Brohan C. Panter R. Arbuckle W. Jessner M. Beumont 《Journal of viral hepatitis》2015,22(8):639-650
The value of adding simeprevir (SMV) vs placebo (PBO) to peginterferon and ribavirin (PR) for treatment of chronic hepatitis C virus infection was examined using patient‐reported outcomes (PROs); further, concordance of PROs with virology endpoints and adverse events (AEs) was explored. Patients (n = 768 SMV/PR, n = 393 PBO/PR) rated fatigue (FSS), depressive symptoms (CES‐D) and functional impairment (WPAI: Hepatitis C Productivity, Daily Activity and Absenteeism) at baseline and throughout treatment in three randomised, double‐blind trials comparing the addition of SMV or PBO during initial 12 weeks of PR. PR was administered for 48 weeks (PBO group) and 24/48 weeks (SMV group) using a response‐guided therapy (RGT) approach. Mean PRO scores (except Absenteeism) worsened from baseline to Week 4 to the same extent in both groups but reverted after Week 24 for SMV/PR and only after Week 48 for PBO/PR. Accordingly, there was a significantly lower area under the curve (baseline–Week 60, AUC60) and fewer weeks with clinically important worsening of scores in the SMV/PR group at any time point. Incidences of patients with fatigue and anaemia AEs were similar in both groups, but FSS scores showed that clinically important increases in fatigue lasted a mean of 6.9 weeks longer with PBO/PR (P < 0.001). PRO score subgroup analysis indicated better outcomes for patients who met the criteria for RGT or achieved sustained virological response 12 weeks post‐treatment (SVR12); differences in mean PRO scores associated with fibrosis level were only observed with PBO/PR. Greater efficacy of SMV/PR enabled reduced treatment duration and reduced time with PR‐related AEs without adding to AE severity. 相似文献
5.
6.
7.
8.
9.
The midwifery art has emphasised the uniqueness of human beings throughout its Nordic history. The educated Nordic midwife has in the last decade celebrated several hundred years of memories. This article studies how the key ideas of the midwifery art and patterns of ideas become evident in the zeitgeist from the beginning of the 19th century to the millennium in the Nordic countries. The legacy and pattern of ideas of the art of midwifery are interpreted in relation to the texts of the selected historical sources and based on Ricoeur's phenomenological-hermeneutic approach to the text and further to the dedication of understanding and interpretation. The historical sources refer to unprinted primary sources from historical archives and printed secondary and tertiary sources. The patterns of ideas include a tripartite whole: the true cultivation of the head, the philosophy and aesthetics of the hand, the strength of the heart and the drive of calling. These ideas open for unique visions and attest to the evident in modern midwives. Today's midwives have academic training with examinations, and the education is based on scientific evidence. The midwife profession is authorised by the state and supervised by the authorities. 相似文献
10.
Xiaojie Wu Leyan Zhang Jiadi Zhou Luying Liu Qiang Fu Aili Fu Xiaoying Feng Rui Xin Hongrui Liu Yong Gao Jiangnan Xue 《Current problems in cancer》2019,43(1):18-26