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H W Losken W M Morris P B Uys J W Earle P A Le Roux E Ackermann 《Suid-Afrikaanse tydskrif vir geneeskunde》1988,73(10):575-577
Trauma to the orbital region may result in fractures of the bony orbit, displacement of which gives rise to malposition of the eye and diplopia. If initial treatment is not feasible or is unsuccessful, later correction may be achieved by osteotomy or reduction and stabilisation of the bony fragments, often with bone grafts. Displaced medial or lateral canthi may need to be repositioned, where feasible in an overcorrected position. Where bone grafts are necessary, the skull is now favoured as the best donor site. 相似文献
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H. -W. Ackermann P. Auclair S. Basavarajappa H. P. Emadi Konjin C. Savanurmath 《Archives of virology》1994,137(1-2):185-190
Summary Preparations of silkworm larvae contained two large phages with contractile tails (Myoviridae). One phage was active onPseudomonas paucimobilis. The other, not cultivated, was one of the largest viruses known. 相似文献
5.
Hess B; Hasler-Strub U; Ackermann D; Jaeger P 《Nephrology, dialysis, transplantation》1997,12(7):1362-1368
BACKGROUND: Metabolic evaluation in recurrent idiopathic calcium renal
stone-formers (RCSF) was analysed with respect to the following questions:
(1) do three 24-h urines provide more diagnostic accuracy in the metabolic
evaluation of RCSF than 1 or 2 urines?; (2) does time after stone event
influence the diagnostic yield?; (3) is urine composition at weekends
different from that at mid-week?; (4) what are the prevalences of the most
important risk factors (RF) of idiopathic calcium nephrolithiasis, i.e. low
volume (LV), hypercalciuria (HC), hyperoxaluria (HO), hyperuricosuria (HU),
hypocitraturia (Hypo-Cit), and hypomagnesiuria (Hypo-Mg)?; and (5) do male
RCSF differ from females with respect to urinary RFs? METHODS: Seventy-five
RCSF (59 men, 16 women) collected three 24-h urines (U1-3) while on
free-choice diet. To account for possible variations in lifestyle and diet,
U1 and U3 had to be collected midweek and U2 at a weekend. RESULTS: When
considering all three urines together (U1 + U2 + U3), the number of RF
abnormalities/patient was 2.8 +/- 0.1, higher than numbers of any
combination of two urines or of any single urine (P = 0.0001 for all
comparisons). The number of RF abnormalities also rose with time after
stone event, from 0.8 +/- 0.1 (range 0-4) in U1 to 1.1 +/- 0.1 (range 0- 4)
in U3 (P = 0.011 vs U1). Whereas all other RF did not change between
collections, urine volume was lower in U2 (1793 +/- 90 ml) than in U1 (2071
+/- 97 ml, P = 0.0001 vs U2) and U3 (1946 +/- 97 ml, P = 0.046 vs U2). At
least 1 abnormality was found in 85.3% of all RCSF, and multiple
abnormalities occurred in 47%. The most frequent RF was HC (39%), followed
by HO and LV (32% each), Hypo-Cit (29%), HU (23%) and Hypo-Mg (19%). Males
more often had Hypo-Cit (P < 0.001) and Hypo-Mg (P < 0.01) than
females, whereas HO was more frequent in female RCSF (P < 0.025 vs
males). CONCLUSIONS: Diagnostic accuracy of metabolic evaluation in RCSF
increases both with the number of urines collected and the time passing
after a stone event. Urines collected at weekends differ from those of the
week only by their lower volumes. Abnormalities of RF for calcium
nephrolithiasis can be detected in 85.3% of RCSF, and HC is the most common
RF both in male and female RCSF.
相似文献
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Two patients were seen with malignant neoplastic emboli to the coronary arteries. One, a 61-year-old woman with a malignant fibrous histiocytoma of the thigh and a solitary pulmonary metastatic lesion, died of an acute myocardial infarction due to a neoplastic coronary embolus after lobectomy. The other, a 51-year-old woman with bronchogenic adenocarcinoma, died of extensive cerebral metastases. At autopsy, she also was found to have had an acute myocardial infarction associated with a neoplastic coronary embolus. 相似文献
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To study the pathogenesis of atrophic rhinitis, gnotobiotic pigs (n = 6) were inoculated intranasally with a sterile sonicate of a toxigenic strain of Bordetella bronchiseptica (0.16 mg of protein per ml) at 5 days of age, and they were then inoculated intranasally with 1 ml (5,250 CFU/ml) of a live, toxigenic strain of Pasteurella multocida at 7 days of age. Pigs were necropsied at 2, 5, 9, 14, 21, and 28 days postinoculation; those pigs necropsied after 5 days had developed turbinate atrophy. Other gnotobiotic pigs received the following inoculation protocols: (i) a sterile sonicate of a nontoxigenic strain of B. bronchiseptica (0.2 mg of protein per ml), followed by toxigenic P. multocida (n = 4); (ii) toxigenic P. multocida alone (n = 7); (iii) diluent (sterile tryptose broth) (n = 2); (iv) the sterile sonicate of toxigenic B. bronchiseptica alone (n = 2); or (v) the sterile sonicate of a nontoxigenic strain of B. bronchiseptica alone (n = 2). Turbinate atrophy did not occur in the latter groups except for one pig inoculated with only toxigenic P. multocida. These studies show that turbinate atrophy occurs in pigs given the toxigenic B. bronchiseptica sonicate and then given live, toxigenic P. multocida. This experimental regimen is a useful model for (i) studying the pathogenesis of atrophic rhinitis and (ii) testing vaccine strategies. 相似文献
10.
Quantification of feline herpesvirus 1 DNA in ocular fluid samples of clinically diseased cats by real-time TaqMan PCR 下载免费PDF全文
Vögtlin A Fraefel C Albini S Leutenegger CM Schraner E Spiess B Lutz H Ackermann M 《Journal of clinical microbiology》2002,40(2):519-523
A fluorogenic PCR was established for the quantification of feline herpesvirus 1 (FeHV-1) DNA in ocular fluid samples of clinically diseased cats. The new assay was specific for FeHV-1 and sensitive. The 100% detection rate ranged from 0.6 to 6 50% tissue culture infective doses per sample. When spiked samples with known quantities of virus were used, infectious virus titers and quantification of viral DNA by PCR correlated to each other in a linear fashion (R(2) = 0.9858) over a range of 4 orders of magnitude. Within this range, it was possible to calculate the FeHV-1 DNA content from a given infectious dose, and vice versa. The new diagnostic procedure was applied to ocular fluid samples from cats experimentally infected with FeHV-1 and specific FeHV-1-free cats. A good correlation between virus titer and quantitative PCR was observed, although only early in infection. In a second stage, the titer of infectious virus collapsed, while the PCR signal remained high. A constantly decreasing PCR signal accompanied by negative virus isolation was characteristic for a final stage of the infection. Finally, clinical samples from 20 cats that were suspected to suffer from FeHV-1 infection were analyzed. By comparing virus titers and quantitative PCR signals, it was possible to determine the current stage of the ongoing infection. Based on these findings, comparison of the results of consecutive samples allows the tracking of the course of the infection. Therefore, the new method combines the advantages of the two previously established conventional methods, qualitative PCR and virus isolation and titration. 相似文献