全文获取类型
收费全文 | 31203篇 |
免费 | 1731篇 |
国内免费 | 107篇 |
专业分类
耳鼻咽喉 | 411篇 |
儿科学 | 682篇 |
妇产科学 | 650篇 |
基础医学 | 4056篇 |
口腔科学 | 2610篇 |
临床医学 | 2338篇 |
内科学 | 6527篇 |
皮肤病学 | 649篇 |
神经病学 | 2417篇 |
特种医学 | 648篇 |
外国民族医学 | 2篇 |
外科学 | 3424篇 |
综合类 | 235篇 |
一般理论 | 7篇 |
预防医学 | 3897篇 |
眼科学 | 436篇 |
药学 | 2467篇 |
中国医学 | 286篇 |
肿瘤学 | 1299篇 |
出版年
2023年 | 244篇 |
2022年 | 645篇 |
2021年 | 1089篇 |
2020年 | 728篇 |
2019年 | 888篇 |
2018年 | 1102篇 |
2017年 | 801篇 |
2016年 | 843篇 |
2015年 | 990篇 |
2014年 | 1290篇 |
2013年 | 1615篇 |
2012年 | 2281篇 |
2011年 | 2499篇 |
2010年 | 1290篇 |
2009年 | 1009篇 |
2008年 | 1744篇 |
2007年 | 1775篇 |
2006年 | 1478篇 |
2005年 | 1333篇 |
2004年 | 1169篇 |
2003年 | 1088篇 |
2002年 | 951篇 |
2001年 | 684篇 |
2000年 | 660篇 |
1999年 | 516篇 |
1998年 | 201篇 |
1997年 | 144篇 |
1996年 | 123篇 |
1995年 | 121篇 |
1994年 | 115篇 |
1993年 | 97篇 |
1992年 | 320篇 |
1991年 | 277篇 |
1990年 | 286篇 |
1989年 | 241篇 |
1988年 | 222篇 |
1987年 | 152篇 |
1986年 | 192篇 |
1985年 | 157篇 |
1984年 | 117篇 |
1983年 | 99篇 |
1982年 | 80篇 |
1979年 | 145篇 |
1975年 | 76篇 |
1974年 | 77篇 |
1973年 | 77篇 |
1970年 | 74篇 |
1969年 | 97篇 |
1968年 | 74篇 |
1967年 | 87篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Selwyn Arlington Headley Nayara Emily Viana Mariana de Mello Zanim Michelazzo Ana Aparecida Correa Xavier Cícero Júlio Silva Costa Felipe Hideki Ogo de Pinho Marcelo Diniz dos Santos 《Transboundary and Emerging Diseases》2020,67(Z2):49-59
Neorickettsia helminthoeca (NH), the agent of salmon poisoning disease or canine neorickettiosis (CN), is a bacterial endosymbiont of the nematode Nanophyetus salmincola, and infections are spreading among specific fish‐eating mammalians. This article describes the pathologic and immunohistochemical findings associated with spontaneous NH‐induced infections in dogs from Southern Brazil. The principal pathologic findings were hypertrophy of Peyer patches and lymphadenopathy with lymphocytic proliferation, chronic interstitial pneumonia, and chronic enteritis associated with positive intralesional immunoreactivity to antigens of NH within macrophages and histiocytes. Positive immunoreactivity against canine parvovirus‐2 (CPV‐2) or/and canine distemper virus was not detected in the evaluated intestinal segments or in the samples from the cerebellum and lungs, respectively, from the dogs evaluated. These findings demonstrated that NH was involved in the enteric, pulmonary, and lymphoid lesions herein described, and provide additional information to confirm the occurrence of this bacterial endosymbiont within this geographical location. It is proposed that chronic pneumonia should be considered as a pathologic manifestation of NH‐induced infections. Additionally, our results show that the occurrences of CN seem to be underdiagnosed in Southern Brazil due to the confusion with the incidence of CPV‐2. 相似文献
2.
3.
Iclea Rocha Gama Euclides Marinho Trindade-Filho Suzana Lima Oliveira Nassib Bezerra Bueno Isabelle Tenório Melo Cyro Rego Cabral-Junior Elenita M. Barros Jaqueline A. Galvão Wanessa S. Pereira Raphaela C. Ferreira Bruna R. Domingos Terezinha da Rocha Ataide 《Metabolic brain disease》2015,30(1):93-98
4.
5.
Talita da Silva Mendes de Farias Ariclécio Cunha de Oliveira Sandra Andreotti Fernanda Gaspar do Amaral Patrícia Chimin André Ricardo Alves de Proença Francisco Leonardo Torres Leal Rogério Antonio Laurato Sertié Amanda Baron Campana Andressa Bolsoni Lopes Arnaldo Henrique de Souza José Cipolla‐Neto Fabio Bessa Lima 《Journal of pineal research》2015,58(3):251-261
Melatonin, the main hormone produced by the pineal gland, is secreted in a circadian manner (24‐hr period), and its oscillation influences several circadian biological rhythms, such as the regulation of clock genes expression (chronobiotic effect) and the modulation of several endocrine functions in peripheral tissues. Assuming that the circadian synchronization of clock genes can play a role in the regulation of energy metabolism and it is influenced by melatonin, our study was designed to assess possible alterations as a consequence of melatonin absence on the circadian expression of clock genes in the epididymal adipose tissue of male Wistar rats and the possible metabolic repercussions to this tissue. Our data show that pinealectomy indeed has impacts on molecular events: it abolishes the daily pattern of the expression of Clock, Per2, and Cry1 clock genes and Pparγ expression, significantly increases the amplitude of daily expression of Rev‐erbα, and affects the pattern of and impairs adipokine production, leading to a decrease in leptin levels. However, regarding some metabolic aspects of adipocyte functions, such as its ability to synthesize triacylglycerols from glucose along 24 hr, was not compromised by pinealectomy, although the daily profile of the lipogenic enzymes expression (ATP‐citrate lyase, malic enzyme, fatty acid synthase, and glucose‐6‐phosphate dehydrogenase) was abolished in pinealectomized animals. 相似文献
6.
7.
8.
Objective
To explore from a gender perspective the association with subjective health of the interaction between education and household arrangements within the framework of social determinants of health placed at the micro and mezzo levels.Methods
The data comes from the Spanish sample of the European Union Statistics on Income and Living Conditions for 2014. Independent logistic regression models for men and women were run to analyze the association with subjective health of the interaction between education and household arrangements. An additive model was run to assess possible advantages over the interaction approach.Results
The interaction models show a lower or even no significant effect on health of household arrangements usually negatively associated with health among individuals with high education, displaying specific patterns according to sex.Conclusions
Health profiles of women and men are more precisely drawn if both social determinants of health are combined. Among the women, the important role was confirmed of both social determinants of health in understanding their health inequalities. Among the men, mainly those with low educational achievement, the interaction revealed that the household was a more meaningful social determinant of health. This could enable the definition of more efficient public policies to reduce health and gender inequalities. 相似文献9.
10.