全文获取类型
收费全文 | 1927篇 |
免费 | 112篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 79篇 |
妇产科学 | 10篇 |
基础医学 | 268篇 |
口腔科学 | 17篇 |
临床医学 | 138篇 |
内科学 | 419篇 |
皮肤病学 | 36篇 |
神经病学 | 191篇 |
特种医学 | 44篇 |
外科学 | 368篇 |
综合类 | 9篇 |
一般理论 | 31篇 |
预防医学 | 199篇 |
眼科学 | 11篇 |
药学 | 56篇 |
中国医学 | 1篇 |
肿瘤学 | 164篇 |
出版年
2022年 | 14篇 |
2021年 | 22篇 |
2020年 | 18篇 |
2019年 | 25篇 |
2018年 | 31篇 |
2017年 | 37篇 |
2016年 | 34篇 |
2015年 | 41篇 |
2014年 | 48篇 |
2013年 | 62篇 |
2012年 | 96篇 |
2011年 | 108篇 |
2010年 | 75篇 |
2009年 | 69篇 |
2008年 | 136篇 |
2007年 | 115篇 |
2006年 | 119篇 |
2005年 | 115篇 |
2004年 | 98篇 |
2003年 | 108篇 |
2002年 | 103篇 |
2001年 | 25篇 |
2000年 | 17篇 |
1999年 | 19篇 |
1998年 | 29篇 |
1997年 | 34篇 |
1996年 | 28篇 |
1995年 | 31篇 |
1994年 | 21篇 |
1993年 | 15篇 |
1992年 | 15篇 |
1991年 | 33篇 |
1990年 | 13篇 |
1989年 | 16篇 |
1988年 | 15篇 |
1986年 | 9篇 |
1985年 | 10篇 |
1984年 | 10篇 |
1983年 | 17篇 |
1982年 | 19篇 |
1981年 | 18篇 |
1979年 | 18篇 |
1977年 | 11篇 |
1976年 | 11篇 |
1975年 | 15篇 |
1974年 | 12篇 |
1973年 | 14篇 |
1971年 | 14篇 |
1968年 | 8篇 |
1967年 | 10篇 |
排序方式: 共有2047条查询结果,搜索用时 0 毫秒
1.
2.
Olle Zetterström Christer Andersson Leif Eriksson ers Fredriksson Johan Friskopp Gunnar Heden Bernt Jansson Tord Lundgren Rolf Nilveus ers Olsson Stefan Renvert Lars Salonen Lars Sjöström ers Winell ers Östgren Stina Gestrelius 《Journal of clinical periodontology》1997,24(9):697-704
Abstract The aim of the present clinical trial was to test tolerability during 2 treatments with EMDOGAIN® in a large number of patients. An open, controlled study design in 10 Swedish specialist clinics was chosen, with a test group of 107 patients treated with EMDOGAIN® in connection with periodontal surgery at 2 surgical test sites per patient. The procedures were performed 2 to 6 weeks apart on one-rooted teeth with at least 4 mm deep intraosseous lesions. A control group of 33 patients underwent flap surgery without EMDOGAIN® at I comparable site. In total 214 test and 33 control surgeries were performed. Serum samples were obtained from test patients for analysis of total and specific antibody levels. 10 of the patients had samples taken before and after the first surgery. 56 other samples were taken after one treatment with EMDOGAIN®, and 63 after 2 treatments. None of the samples, not even from allergy-prone patients after 2 treatments, indicated deviations from established baseline ranges. This indicates that the immunogenic potential of EMDOGAIN® is extremely low when applied in conjunction with periodontal surgery. Comparison between the test and control groups demonstrated the same type and frequency of post-surgical experiences, i.e., reactions caused by the surgical procedure itself. Clinical probing and radiographic evaluation was performed at baseline and 8 months postsurgery. About half of the patients (44 test and 21 control) were also evaluated after 3 years. There was a significant difference between the test and control results at 8 months post surgery. and this difference had increased further at the 3 year follow-up. The 2.5–3 mm increase in attachment and bone level after treatment with EMDOGAIN® was of the same magnitude as seen in the studies with split-mouth design aiming for lest of effectiveness of EMDOGAIN®. 相似文献
3.
4.
Per H. Morberg Olle G. P. Isaksson Carina B. Johansson Jonas Sandstedt Jan F. T rnell 《Acta orthopaedica》1997,68(4):344-348
Several recent studies have investigated the effects of growth hormone (GH) on the healing of fractures and bone ingrowth, but with conflicting results. The negative results may be due to antibody formation against injected GH or because some experimental models are able to prove only positive GH effects. In this study, we wanted to investigate the effect of GH on implant integration in bone. To avoid potential formation of antibodies against injected GH, we used a model with transgenic mice overexpressing bovine GH (bGH).
Titanium implants were inserted in the forehead of the mice. 4 months after insertion, the implants were cut out en bloc with the surrounding bone. The calcified specimens were cut and ground to a thickness of approximately 10m. Histomorphometry demonstrated significantly more direct bone-to-metal contact in the transgenic mice than in the nontransgenic littermates. Our findings indicate that systemic administration of GH in humans may improve implant integration in bone. 相似文献
Titanium implants were inserted in the forehead of the mice. 4 months after insertion, the implants were cut out en bloc with the surrounding bone. The calcified specimens were cut and ground to a thickness of approximately 10m. Histomorphometry demonstrated significantly more direct bone-to-metal contact in the transgenic mice than in the nontransgenic littermates. Our findings indicate that systemic administration of GH in humans may improve implant integration in bone. 相似文献
5.
Gsta Berlin Aril Frydn Rolf Maller Claes Malm Olle Vikrot 《European journal of haematology》1981,25(2):171-174
At our hospital 15 cases of leukaemic reticuloendotheliosis and 4 cases of Legionnaires' disease have been diagnosed. 3 patients had both diseases. The clinical findings are reported. It is probable that patients with leukaemic reticuloendotheliosis have an increased susceptibility to Legionnaires' disease. Possible reasons for the decreased resistance are discussed. 相似文献
6.
We assessed the feasibility and psychometric properties of two commonly used health status questionnaires in Parkinson's disease (PD): the generic Nottingham Health Profile (NHP) and the disease-specific 39-item Parkinson's disease Questionnaire (PDQ-39), from a cross-sectional postal survey of PD patients (N = 81), using traditional and Rasch measurement methodologies. Overall response rate was 88%. Both questionnaires were found feasible, although the NHP performed less well. The PDQ-39 had fewer floor effects and was better able to separate respondents into distinct groups than the NHP, whereas the latter exhibited less ambiguous dimensionality and better targeting of respondents with non-extreme scores. Reliability and validity indices were similar, and potential differential item functioning by age and gender groups was found for both questionnaires. PDQ-39 response alternatives indicated ambiguity. With few exceptions, questionnaire scales were unable to meet recommended standards fully. While preliminary, this study illustrates the need for thorough evaluation of outcome measures and has implications beyond the questionnaires used here. Although promising, both questionnaires warrant further developmental work and stronger support of measurement validity before they could be considered fully suitable for valid use in PD, in particular in earlier stages of the disease. 相似文献
7.
8.
Amir?R?RazaviEmail author Hans?Gill Olle?St?l Marie?Sundquist Sten?Thorstenson Hans??hlfeldt Nosrat?Shahsavar the South-East Swedish Breast Cancer Study Group 《BMC medical informatics and decision making》2005,5(1):29
Background
A common approach in exploring register data is to find relationships between outcomes and predictors by using multiple regression analysis (MRA). If there is more than one outcome variable, the analysis must then be repeated, and the results combined in some arbitrary fashion. In contrast, Canonical Correlation Analysis (CCA) has the ability to analyze multiple outcomes at the same time. 相似文献9.
10.
J. Alumets G. Ekelund R. Håkanson O. Ljungberg U. Ljungqvist F. Sundler S. Tibblin 《Virchows Archiv : an international journal of pathology》1978,378(1):17-22
Summary A case of malignant endocrine tumour of the jejunum, associated with severe duodenal ulcer is described. The tumour and a local metastasis were examined by immunohistochemistry and found to contain abundant somatostatin-immunoreactive cells together with less numerous cells displaying gastrin immunoreactivity. This is to our knowledge the first case of intestinal somatostatinoma. The presence of gastrin cells in the tumour may explain the ulcer diathesis. 相似文献