全文获取类型
收费全文 | 737篇 |
免费 | 43篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 29篇 |
妇产科学 | 8篇 |
基础医学 | 103篇 |
口腔科学 | 4篇 |
临床医学 | 54篇 |
内科学 | 168篇 |
皮肤病学 | 9篇 |
神经病学 | 21篇 |
特种医学 | 8篇 |
外科学 | 123篇 |
综合类 | 31篇 |
一般理论 | 1篇 |
预防医学 | 45篇 |
眼科学 | 57篇 |
药学 | 27篇 |
肿瘤学 | 90篇 |
出版年
2023年 | 9篇 |
2022年 | 28篇 |
2021年 | 49篇 |
2020年 | 18篇 |
2019年 | 18篇 |
2018年 | 28篇 |
2017年 | 24篇 |
2016年 | 26篇 |
2015年 | 31篇 |
2014年 | 26篇 |
2013年 | 45篇 |
2012年 | 54篇 |
2011年 | 51篇 |
2010年 | 31篇 |
2009年 | 25篇 |
2008年 | 27篇 |
2007年 | 26篇 |
2006年 | 26篇 |
2005年 | 26篇 |
2004年 | 34篇 |
2003年 | 24篇 |
2002年 | 19篇 |
2001年 | 8篇 |
2000年 | 10篇 |
1999年 | 11篇 |
1998年 | 5篇 |
1997年 | 4篇 |
1996年 | 4篇 |
1994年 | 3篇 |
1992年 | 3篇 |
1991年 | 5篇 |
1990年 | 4篇 |
1989年 | 3篇 |
1988年 | 6篇 |
1986年 | 5篇 |
1985年 | 3篇 |
1983年 | 4篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 6篇 |
1976年 | 2篇 |
1973年 | 2篇 |
1972年 | 3篇 |
1971年 | 5篇 |
1970年 | 7篇 |
1969年 | 6篇 |
1968年 | 6篇 |
1967年 | 8篇 |
1966年 | 2篇 |
1965年 | 2篇 |
排序方式: 共有782条查询结果,搜索用时 9 毫秒
1.
Detecting collinear dots in noise 总被引:1,自引:0,他引:1
We estimated the sensitivity for detecting a row of collinear target elements (usually dots) by measuring the maximum density of randomly positioned noise elements that allowed 75% correct detection of the orientation of alignment (binary choice: horizontal versus vertical) of the target elements. We varied the number of target elements, their mode of generation, and their accuracy of positioning. As reported previously (Moulden (1994) Higher-order processing in the visual system. Ciba Foundation Symposium 184. Chichester: Wiley), target detection improved rapidly until the number of target elements reached about seven, and then improved more slowly beyond this point. However, this break was reduced (and often removed entirely) when the target array was formed by repositioning pre-existing noise elements lying close to the target location, rather than by superimposition of additional target elements onto the noise array. This almost linear slope of improvement, coupled with the observation that target detection was disrupted more by random jitter of target elements at right angles to their axis of alignment than by jittering along this axis, argues against a two-stage process of perceptual grouping (Moulden, 1994) and supports instead an explanation based on the operation of a single mechanism. This single mechanism explanation is further supported by the observation that intrinsic positional uncertainty (estimated from the results of jitter experiments) was independent of target element number. Additional experiments showed that target detection is facilitated by aperiodic noise dots that fall close to the target axis. The results are discussed in relation to alternative explanations of perceptual grouping. 相似文献
2.
3.
4.
Acute dapsone poisoning is rare and such cases are either accidental or suicidal. Though accidental DDS poisoning are reported in children, the same is fairly uncommon in adults. Only 2 such cases are reported in India literature. We here report 4 cases of fatal sucidial DDS poisoning in adults resulting death in 3 cases. The reported acute symptoms include nausea, vomiting, hyperexcitability followed by depression, Carpopedal spasm or convulsions. The most marked signs are dyspnoea and cyanosis. The symptoms are due to methaemoglobinaemia, and or sulphaemoglobinaemia. Normally dapsone induces red cell haemolysis and even with small therapeutic doses of 25-100 mg per day, and in toxic doses reduces the oxygen carrying capacity of blood and damages the red cells making them more vulnerable for haemolysis. The peculiarity of the presentation in this series are manifestation of severe haemorrhagic episode in one case and progressive jaundice in another besides cyanosis. None of the cases had carpopedal spasm or convulsion. Out of four cases three died inspite of intensive care, intravenous vitamin C, exchange transfusion (2 cases) and other supportive measures. Intravenous methylene blue could not be used in these cases due to non-availability. 相似文献
5.
6.
Role of adenosine receptors in resveratrol‐induced intraocular pressure lowering in rats with steroid‐induced ocular hypertension 下载免费PDF全文
7.
Bhore AV Sastry J Patke D Gupte N Bulakh PM Lele S Karmarkar A Bharucha KE Shrotri A Pisal H Suryawanshi N Tripathy S Risbud AR Paranjape RS Shankar AV Kshirsagar A Phadke MA Joshi PL Brookmeyer RS Bollinger RC 《International journal of STD & AIDS》2003,14(1):37-41
OBJECTIVE: Efforts to prevent HIV transmission from mother to infants in settings like India may benefit from the availability of reliable methods for rapid and simple HIV screening. Data from India on the reliability of rapid HIV test kits are limited and there are no data on the use of rapid HIV tests for screening of pregnant women. METHODS: Pregnant women attending an antenatal clinic and delivery room in Pune agreed to participate in an evaluation of five rapid HIV tests, including (a) a saliva brush test (Oraquick HIV-1/2, Orasure Technologies Inc.), (b) a rapid plasma test (Oraquick HIV-1/2) and (c) three rapid finger prick tests (Oraquick HIV-1/2; HIV-1/2 Determine, Abbott; NEVA HIV-1/2 Cadila). Results of the rapid tests were compared with three commercial plasma enzyme immunoassay (EIA) tests (Innotest HIV AB EIA, Lab systems/ELISCAN HIV AB EIA, UBI HIV Ab EIA). RESULTS: Between September 2000 and October 1, 2001, 1258 pregnant women were screened for HIV using these rapid tests. Forty-four (3.49%) of the specimens were HIV-antibody-positive by at least two plasma EIA tests. All of the rapid HIV tests demonstrated excellent specificity (96-100%). The sensitivity of the rapid tests ranged from 75-94%. The combined sensitivity and specificity of a two-step algorithm for rapid HIV testing was excellent for a number of combinations of the five rapid finger stick tests. CONCLUSION: In this relatively low HIV prevalence population of pregnant women in India, the sensitivity of the rapid HIV tests varied, when compared to a dual EIA algorithm. In general, the specificity of all the rapid tests was excellent, with very few false positive HIV tests. Based upon these data, two different rapid HIV tests for screening pregnant women in India would be highly sensitive, with excellent specificity to reliably prevent inappropriate use of antiretroviral therapy for prevention of vertical HIV transmission. 相似文献
8.
9.
Barsha Dassarma Satyajit Tripathy Motlalepula Matsabisa 《Transfusion Clinique et Biologique》2021,28(1):123-127
Since December 2019, the human populations of the 195 global countries continue experiencing grave health and life threats due to the current COVID-19 pandemic. As a result of the novelty of the pathogen, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), at present there is lack of preventive as well as therapeutic options for treating and managing the infection. The use of ancient immunotherapeutic technique – the convalescent plasma (CP) therapy, may act as an immediate and available option to control the COVID-19 pandemic. This review provides a concept and understanding on the CP therapy, its potential to control SARS-CoV-2 pandemic. The CP therapy might act as an immediate saviour for society from the virus. Although the CP therapy has exert affirmative result against COVID-19 it has not been recommended for long time use in COVID-19 and this review gives support for its possible application. 相似文献
10.
Anish Adhikari Swetapadma Tripathy Sarah Chuzi Jonna Peterson Neil J. Stone 《Journal of clinical lipidology》2021,15(1):22-32.e12
The US Food and Drug Administration issued a black box warning in 2012 regarding the association of statin use with cognitive impairment. This may deter patients and practitioners from using statins for guideline-directed indications. Large studies have not shown an increase in cognitive impairment with statin use. MEDLINE, EMBASE, and Cochrane databases were searched up to October 2019. We present an up-to-date systematic review of randomized controlled trials (RCTs) and prospective observational studies examining the association between statin use and cognitive status in a population aged ≥60 years. Twenty-four studies with 1,404,459 participants were included in the review. Twenty-one were prospective observational studies, and 3 were RCTs. All 3 RCTs, which ranged from 3.2 to 5.6 years of follow-up, showed no significant association between statin use and adverse cognitive effects (odds ratio [OR] 1.03 [0.82–1.30]) and (OR 1.0 [0.61–1.65]). The mean difference in the Mini-Mental State Examination was insignificant (0.06 [?0.04 to 0.16]) in the third RCT. The follow-up for observational studies ranged from 3 to 15 years. Ten observational studies showed reduced incidence of dementia. Seven showed no association with incident dementia. Three studies showed decline in cognition was similar, whereas one showed slower decline with statin use. There was no evidence of adverse cognitive effects, including incidence of dementia, deterioration in global cognition, or specific cognitive domains associated with statin use in individuals aged ≥60 years. Future studies should examine this association in studies with longer follow-up periods. 相似文献