关于癌症患者"坚强"的概念分析

全文以Walker和Avant概念分析格式介绍坚强（hardiness）的定义和特征,说明案例,分析前置因子和后果,列举坚强的评估方法和在不同人群中的运用.希望通过对坚强的全面分析加深医务人员对此概念的理解,从而有助于激发患者的坚强特质.     

AC/A ratios in myopic and emmetropic Hong Kong children and the effect of timolol§

Purpose: Caucasian children with myopia have elevated response accommodative vergence to accommodation (AC/A) ratios. The purpose of this study was twofold: to determine if response AC/A ratios vary with refractive error and with myopic progression rate in Hong Kong Chinese children, and to determine the effect of beta‐adrenergic antagonism with topical timolol application on AC/A ratios. Methods: Thirty children aged eight to 12 years participated in the study. All refractive errors were corrected with spectacle lenses. Accommodative responses were measured using a Shin‐Nippon autorefractor and concurrent changes in vergence were assessed using a vertical prism and a Howell‐Dwyer card at three metres and 0.33 metre. Accommodative demand was altered using plus or minus two dioptre lenses and lens‐ and distance‐induced response AC/A ratios were calculated. Measurements were repeated 30 minutes after the instillation of topical timolol maleate (0.5 per cent). Results: AC/A ratios appeared higher in progressing myopic children but the difference was not statistically significant. Timolol application reduced accommodative convergence (AC) in the stable myopes (reduction = ‐3 ± 1.14^A) but not in the emmetropes (0.69 ± 0.9^P) or progressing myopes (0.16 ± 0.43^A) and this difference between refractive groups was statistically s ignificant (F^2,27= 3.766; P= 0.036). However, timolol did not produce a significant change in the accommodative response to positive or negative lenses or response AC/A ratios. Conclusions: We did not find that AC/A ratios in myopic Chinese children were elevated and therefore, it is unlikely that elevated AC/A ratios are responsible for the high levels of myopia that occur in Hong Kong. The finding that timolol reduced AC in the stable myopes suggests that the autonomic control of accommodative convergence in these children may be different from that in emmetropic children and those with progressing myopia.     

60例急性病毒性脑炎的临床分析

目的　评价急性病毒性脑炎的诊断与治疗。方法　收集 1993～ 2 0 0 1年 6月的住院病案 60份 ,就临床症状、神经体征、周围血白细胞计数和分类、脑脊液、脑电图、脑CT检查 ,以及单用激素组和激素 +抗病毒毒药组之间的疗效关系进行分析。结果　本组病毒性脑炎可分为六种临床类型 :精神异常 ;持续性剧烈头痛伴呕吐 ;强直 -阵挛性抽搐 ;持续性意识障碍 ;脑神经损害、失语、偏瘫 ;小脑性共济失调。前三型最为常见 ,并且三型之间的临床现象有相互穿插出现的现象。经统计学处理 ,单用激素组与激素 +抗病药物组之间的疗效无显著性差异。结论　急性病毒性脑炎为一种自限性疾病 ,但在没有病毒学检查的情况下 ,尚应和急性播散性脑脊髓炎或多发性硬化作鉴别     

亚甲蓝及粘弹剂在泪囊鼻腔吻合术中的应用

目的:探讨亚甲蓝及粘弹剂在泪囊鼻腔吻合术中的应用价值。方法:对慢性泪囊炎患者21例21眼(其中6例6眼为小泪囊慢性泪囊炎)施行泪囊鼻腔吻合手术,术中应用亚甲蓝及粘弹剂。术后随访3mo～1a,观察手术疗效。结果:所有21眼中治愈19眼,好转2眼,治愈率90.5%,总有效率100.0%。其中6眼小泪囊慢性泪囊炎中治愈4眼,好转2眼。结论:亚甲蓝及粘弹剂在泪囊鼻腔吻合术中的应用可有效提高手术成功率,小泪囊慢性泪囊炎可作为泪囊鼻腔吻合术的手术适应证。     

急性脑梗死患者血浆NO及GMP-140水平与梗死面积的关系及其临床意义

目的探讨梗死面积不同的急性脑梗死患者血浆一氧化氮(NO)及血小板α颗粒膜蛋白(GMP-140)水平及其临床意义。方法采用硝酸还原法和双抗体夹心酶联吸附法测定116例急性脑梗死患者进行血浆NO及GMP-140水平,并分别和41例正常对照组比较,同时将脑梗死的血浆NO及GMP-140水平作直线相关分析。结果脑梗死组患者血浆NO含量显著低于正常对照组(P<0.01),血浆NO含量与梗死灶大小明显负相关(P<0.01);脑梗死组患者血浆GMP-140含量高于正常对照组(P<0.01),血浆GMP-140含量与梗死灶呈正相关。急性脑梗死患者血浆NO和GMP-140之间没有直线相关性(r=0.067,P>0.05)。结论急性脑梗死血浆NO及GMP-140水平的测定,对估计梗死灶面积与病情有很重要的价值。     

A mononuclear nine-coordinated Dy(iii) complex exhibiting field-induced single-ion magnetism behaviour

A new mononuclear Dy(iii) complex, with the formula [Dy(Hcpt)₃]·2H₂O (1), has been successfully prepared via self-assembly between Dy(iii) ions and 2-cyano-N′-(1-(pyridin-2-yl)amido)acetyl (Hcpt) ligand. X-ray diffraction study shows that the Dy(iii) ion is nine-coordinated by three Hcpt ligands with a tridentate chelating mode, leading to an approximately monocapped square-antiprismatic (C_4v) geometry. Magnetic data analysis demonstrates that 1 performs field-induced slow magnetic relaxation with a relaxation barrier of 97.90 K, due to the quantum tunneling effect suppressed upon a static dc field of 2000 Oe. To deeply understand the magnetic behaviors, the relaxation mechanisms and magneto-structure relationship are rationally discussed using ab initio calculations as well.

Reaction of Dy(iii) ion with tridentate acylhydrazone ligand leads to a field-induced Dy(iii) SIM, of which the magneto-structural correlation is elucidated by the magnetic and theoretical studies.     

人体肱骨髁上骨折断端旋转角度的数学测算及临床应用

本文在为解决肱骨髁上骨折断端旋转移位对肘内翻发生的影响的研究过程中,发现肱骨髁上骨折横截面的有关轮廓线可用椭圆弧段作近似模拟,经推导出椭圆的宽度公式tgα=((A~2-P~2)/(P~2-B~2))~(1/2)(A=X线照片正位片上较宽折端处宽度,P=正位片上较窄折端处宽度,B=侧位片上较窄断端处宽度)后,代入测量数据计算,基本与实测角度相符.为使计算误差在±5°范围之内,用以45°为中心,向0°方向,每下降10°,计算值相应减1°;向90°方向,每上升10°,计算值相应增加1°的办法修正。此方法,可用于肱骨髁上骨折后断端旋转移位角度计算,用于评价旋转移位对肘内翻的影响,预防和减少肘内翻的发生.     

新型冠状病毒肺炎确诊患者及隔离留观者心理状况的影响因素研究

  目的  了解湖北省居民在新冠肺炎疫情期间的心理健康状况,为进行居民心理指导提供科学依据。  方法  于2020年2月10 — 12日采用滚雪球抽样方法在湖北省抽取1 157名居民进行心理健康问卷调查。  结果  湖北省1 157名居民中,有16.51 %的居民有焦虑症状,且不同年龄、文化程度、婚姻状况和职业居民焦虑状况不同（均P < 0.05）;有51.51 %和13.74 %的居民有中度和高度恐惧,且不同性别和年龄居民恐惧状况不同（均P < 0.05）;有20.22 %和73.38 %的居民对战胜疫情有中度和高度信心,且不同性别、年龄和文化程度居民战胜疫情的信心状况不同（均P < 0.05）;有35.87 %和25.24 %的居民中度和重度担忧因此次疫情而遭受歧视,且不同性别、年龄、文化程度、婚姻状况、职业和居住地居民担心受歧视状况不同（均P < 0.05）。  结论  湖北省居民的心理健康状况因此次新冠肺炎疫情受到不同程度的影响,且不同性别、年龄、文化程度、婚姻状况、职业和居住地也会影响其心理健康状况,因此对湖北省居民应给予早期的有针对性的心理干预措施。     

Quantitative Detection of ID4 Gene Aberrant Methylation in the Differentiation of Myelodysplastic Syndrome from Aplastic Anemia

Background:The diagnosis of myelodysplastic syndrome (MDS),especially hypoplastic MDS,and MDS with low blast counts or normal karyotype may be problematic.This study characterized ID4 gene methylation ...     

Effect on platelet aggregation activity: extracts from 31 Traditional Chinese Medicines with the property of activating blood and resolving stasis

OBJECTIVE

To evaluate the anti-platelet aggregation effects of extracts from 31 Traditional Chinese Medicines (TCM) with the property of activating blood and resolving stasis in terms of TCM theory.