A combination of levonorgestrel 0.15mg and
ethinyl estradiol 0.03mg, an ultra-low dose oral con
traceptive in pellet form, was tried out in 9 Beijing
clinics. A total of l,035 healthy women of reproduc
tive age participated in 9,413 cycles of treatment.
Only one pregnancy was attributed to medication
failure which resulted in a corrected Pearl index of
0.13/100 women-year. The incidence of breakthrough
bleeding and amenorrhea was 0.12% and 0.05% res
pectively. Using the life-table method, the net
cumulative rate of termination due to medical-related
reasons at one year was only 5.93/100 women. The
incidence of side effects was low. The most frequent
complaints were nausea and drowsiness, which re
duced with the increase of treatment cycles. Some
metabolic changes were studied. In comparison
with other OCs used in China, this formula has the
advantages of ultra-low-dose steroids with higher
contraceptive efficacy, better cycle control and
fewer side effects. 相似文献
Twenty five cases, including 26 eyes with retinal vein occlusion (RVO) were examined by means of the electro-oculogram. The results showed that 23 of the 26 eyes suffering from RVO exhibited abnormalities of the electro-oculogram (EOG). The potential difference and Arden ratio in the RVO eyes were lower than those in the normal eyes (P<0.01). The more the visual acuity of ill eyes was decreased, the higher the abnormal rate of EOG in ill eyes was. 14 eyes had the visual acuity less than 0.1, whose EOGs were abnortmal. Six eyes had the visual acuity from 0. 2 to 0. 4, in which the EOGs of 5 eyes were abnormal. Six eyes had the visual acuity more than 0. 5, a-mong which the EOGs of 4 eyes were abnormal. Based on the above observations, it may be considered that the circulatory disturbance resulting from RVO damages not only the internal layer but also the external layer of the retina. We suggest that EOG is a useful method for distingquishing lesions caused by RVO and may reflect the functional condition 相似文献
By digital subtraction angiography(DSA), the authors made observations on 108 normal ophthalmic arteries in 80 patients with regard to the origins, courses, branching, morphology and anastomoses of the vessels. The merits and demerits of DSA in observing the ophthalmic artery were discussed. Eye Science 1994; 10: 157- 162. 相似文献
Since the beginning of this century, trans-
naso-sphenoidal resection of the pituitary fossa
tumors has been widely used clinically. It has
more merits than other operative approaches
used before. In China it has been adopted by
both ENT doctors and neurosurgeons since 1959.1
In order to afford some relevant anatomical
data, we measured 137 adult sagittal plane
skulls with distinct landmarks. 相似文献
Purpose:To report a rare sign, paracentral corneal dellen that developed in a middleaged female patient with Graves ophthalmopathy.Methods:A paracentral corneal dellen developed in the left eye in a 42-year-old woman who was diagnosed as Graves ophthalmopathy. The patient had remarkable upper eyelid retraction, upper eyelid lag and upward motility restriction. The Graves ophthalmopathy was classified as Grade Ⅳ according to NOSPECS classification.Results:Local artificial tear film and 0.3% Tobramycin eye drops were administered to both eyes.Twenty-four hours later, the left corneal dellen disappeared.Conclusions:Graves ophthalmopathy can lead to paracentral corneal dellen because of severe upper eyelid retraction and upward motility restriction of the eye in spite of the lack of lagophthalmos. Artificial tear drop and antibiotic eye drop therapy helped even though the patient did not have corneal exposure. Eye Science 2003;19:174-175. 相似文献
Objective: To study the calcium channel reaction of human Leydig cells induced by hCG/ATP at different extracellular calcium ion concentrations. Methods: The Leydig cell calcium ion concentration was examined with laser confocal microscope, when the cells were stimulated with hCG/ATP at different extracellular calcium contrations. Results: With calcium-containing extracellular fluid, the Leydig cells were sensitive to hCG stimulation and when the extracellular fluid was calcium-free, the Leydig cells did not respond to the stimulation. However, the Leydig cells did respond to ATP stimulation no matter the extracellular fluid contained calcium or not. Conclusion: In human Leydig cells, there are calcium channels sensitive to hCG and ATP. The extracellular calcium ion concentration plays an important role in the regulation of Leydig cell metabolism by hCG/ATP. 相似文献
A perusal of the medical literature re-
vealod only one case of giant nonmetallic in
traocular foreign body, 15x11x7 mm, removed
in China However, no mention was made of
the operative result of the wounded eye in the
report. Usually after removal of intraocular
foriegn bodies, especially the giant ones, the
eyeball becomes inevitably atrophied, thus it
has to be enucleated soon after operation.
We removed a giant intraocular metallic
foreign body, measuring 18.1x9x1.5 mm and
weighing 0.24 g, from the left eye of a patient
at our clinic. Follow-up l year after operation
found that the eyeball of the affected eye was
good in appearance with preservation of partial
vision. 相似文献
Background: Erythrocytes are transfused to improve oxygen delivery and prevent or treat inadequate oxygenation of tissues. Acute isovolemic anemia subtly slows human data processing and degrades memory, increases heart rate, and decreases self-assessed energy level. Erythrocyte transfusion is efficacious in reversing these effects of acute anemia. We tested the hypothesis that increasing arterial oxygen pressure (Pao2) to 350 mmHg or greater would supply sufficient oxygen to be equivalent to augmenting hemoglobin concentration by 2-3 g/dl and thus reverse the effects of acute anemia.
Methods: Thirty-one healthy volunteers, aged 28 +/- 4 yr (mean +/- SD), were tested with verbal memory and standard, computerized neuropsychologic tests before and twice after acute isovolemic reduction of their hemoglobin concentration to 5.7 +/- 0.3 g/dl. Two sets of tests were performed in randomized order at the lower hemoglobin concentration: with the volunteer breathing room air or oxygen. The subject and those administering the tests and recording the results were unaware which gas was administered. As an additional control for duration of the experiment, 10 of these volunteers also completed the same tests on a separate day, without alteration of hemoglobin concentration, at times of the day similar to those on the experimental day. Heart rate, mean arterial blood pressure, and self-assessed sense of energy were recorded at the time of each test.
Results: Reaction time for digit-symbol substitution test increased, delayed memory was degraded, mean arterial pressure and energy level decreased, and heart rate increased at a hemoglobin concentration of 5.7 g/dl (all P < 0.05). Increasing Pao2 to 406 +/- 47 mmHg reversed the digit-symbol substitution test result and the delayed memory changes to values not different from those at the baseline hemoglobin concentration of 12.7 +/- 1.0 g/dl, and decreased heart rate (P < 0.05). However, mean arterial pressure and energy level changes were not altered with increased Pao2 during acute anemia. 相似文献
Plasma testosterone and estradiol are determined
in 72 patients with abnormal high density lipoprotein.
cholesterol (HDL-C) and high density lipoprotein
cholesterol/total cholesterol (H/T) ratio values, and
in 72 randomly chosen males with normal HDLC
and H/T values. The results showed that plasma
testosterone levels in the groups with abnormal
HDL-C and H/T were obviously lower than those
in the controls. Statistically significant differences
were found in all the abnormal groups in comparison
with the controls (P0.20).
Testosterone levels lowered further with increasing
age in the groups with abnormal HDL-C and H/T.,
the most obvious drops were in the groups around
56 years of age (P<0.005). The data indicate that
male hormone deficiency may reduce HDL-C and
H.'T and facilitate the process of atherosclero_is.
Therefore, it seems rational to treat such patients
with male sex hormone preparations or to use the
traditional Chinese medicines which strengthen Yang
(maleness) in a new attempt to treat and prevent
CHD. 相似文献