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目的:观察院内制剂健骨康胶囊对绝经后骨质疏松性骨痛症186例的临床疗效。方法:将186例符合入选条件的患者随机分为2组。治疗组94例和对照组92例,治疗组给予健骨康胶囊4粒/次,每日3次,口服;对照组钙尔奇D1粒/次,每日2次,口服。疗程6个月。结果:两组患者治疗后3~6个月BMD都较治疗前有不同程度增高。以total为显著(增幅2.95%~4.40%),P〈0.01;治疗后两组BMD比较无显著意义。治疗组中54例患者疼痛症状得到显著改善,27例患者轻度改善,总改善率86.17%;对照组显著改善21例,轻度改善29例,总改善率54.35%。两组总改善率经统计学处理有显著差异P<0.05,进一步经ridit分析显示治疗组疗效明显优于对照组。结论:健骨康胶囊对治疗绝经后骨质疏松症有提高骨密度(BMD),缓解骨痛之效果。 相似文献
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目的:观察活血化瘀、止痛类中药配伍治疗胸腰椎骨折的疗效。方法:将胸腰椎骨折病例82例随机分为治疗组42例,男性12例,女性30例;胸椎骨折9例,腰椎骨折28例,胸腰椎合并骨折5例。采用口服传统方剂大成汤加减配合我院自制808伤药膏外敷。对照组40例,男性10例,女性30例;胸椎骨折8例,腰椎骨折29例,胸腰椎合并骨折13例。采用三七总皂甙注射液静点配合外用云南白药气雾剂。结果:治疗组有效率为97.62%;对照组有效率为80%;治疗组疗效明显优于对照组(P<0.05)。结论:该疗法可活血通便,通络止痛,缩短疗程,疗效满意。 相似文献
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This study examined the correlation between osteoporosis and the degeneration of in-tervertebral discs. Sprague-Dawley rats were maintained up to 22 or 28 months. The femoral bone, tibial bone and lumbar vertebra were histologically studied and the expression of collagen type Ⅱ and Ⅹ in intervertebral discs was immunohistochemiscally determined. Several indices for the de-generation of intervertebral discs and osteoporosis and the correlation among them were then ana-lyzed. Close correlations were found among the indices for the degeneration of intervertebral discs, including the relative area of the vascular bud, the ratio of the uncalcified and the calcified layers, the expression of collagen type Ⅱ and Ⅹ. The correlation with collagen type Ⅹ was negative. There existed positive correlations among the indices for osteoporosis, including the thickness ratio of cor-tical bone, the relative area of bone trabecula, the density of femoral and vertebral body bones, and the maximum stress and strain on bone. Analysis on the relationship of osteoporosis and the disease on disc showed that the indices of osteoporosis were negatively correlated with the indices of the de-generation of intervertebral discs but the expression of collagen type Ⅹ was positively correlated, with the density of vertebral body bones having the strongest dependence on collagen type Ⅹ. The maximum stress and strain bore no correlation with the degeneration of intervertebral discs. These results suggest that osteoporosis was negatively correlated with the degeneration of intervertebral discs. 相似文献
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