全文获取类型
收费全文 | 7335篇 |
免费 | 444篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 55篇 |
儿科学 | 106篇 |
妇产科学 | 129篇 |
基础医学 | 805篇 |
口腔科学 | 98篇 |
临床医学 | 911篇 |
内科学 | 1242篇 |
皮肤病学 | 83篇 |
神经病学 | 671篇 |
特种医学 | 442篇 |
外国民族医学 | 1篇 |
外科学 | 844篇 |
综合类 | 73篇 |
一般理论 | 8篇 |
预防医学 | 1032篇 |
眼科学 | 89篇 |
药学 | 529篇 |
中国医学 | 4篇 |
肿瘤学 | 665篇 |
出版年
2024年 | 4篇 |
2023年 | 33篇 |
2022年 | 71篇 |
2021年 | 142篇 |
2020年 | 76篇 |
2019年 | 149篇 |
2018年 | 193篇 |
2017年 | 127篇 |
2016年 | 130篇 |
2015年 | 173篇 |
2014年 | 226篇 |
2013年 | 458篇 |
2012年 | 594篇 |
2011年 | 627篇 |
2010年 | 349篇 |
2009年 | 341篇 |
2008年 | 544篇 |
2007年 | 529篇 |
2006年 | 497篇 |
2005年 | 487篇 |
2004年 | 504篇 |
2003年 | 539篇 |
2002年 | 447篇 |
2001年 | 53篇 |
2000年 | 36篇 |
1999年 | 69篇 |
1998年 | 82篇 |
1997年 | 49篇 |
1996年 | 42篇 |
1995年 | 41篇 |
1994年 | 32篇 |
1993年 | 31篇 |
1992年 | 13篇 |
1991年 | 14篇 |
1990年 | 7篇 |
1989年 | 4篇 |
1988年 | 8篇 |
1987年 | 6篇 |
1986年 | 3篇 |
1985年 | 7篇 |
1984年 | 11篇 |
1983年 | 7篇 |
1982年 | 3篇 |
1981年 | 3篇 |
1980年 | 4篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1930年 | 2篇 |
1926年 | 2篇 |
排序方式: 共有7787条查询结果,搜索用时 15 毫秒
1.
2.
3.
Jeff Anglen Peter Steven Apostoles Gordon Christensen Barry Gainor Joel Lane 《Journal of orthopaedic research》1996,14(2):251-254
We examined the efficacy of various irrigation solutions delivered through a power irrigator to remove bacteria from three different surfaces. Titanium, stainless-steel, and cortical bone surfaces were coated with three different bacterial species: Staphylococcus aureus, Pseudomonas aeruginosa, and Staphylococcus epidermidis. They were then irrigated with 1 L of fluid delivered by jet lavage. The fluids tested were normal saline and solutions of bacitracin, neomycin, and soap. One set of specimens was not irrigated, as a control. After irrigation, the specimens were sonicated to remove residual bacteria, and the sonicate was quantitatively cultured to allow evaluation of the amount of residual bacteria on the surface. The results showed that removal of bacteria reflects an interaction between bacterial species, surface characteristics, and irrigation solution. Fewer bacteria were present in all the irrigation groups than in the control. Soap solution was as good as or better than any other solution at removing all three types of bacteria from all three surfaces, although not all of the pairwise comparisons were statistically significant. There was a significant advantage to soap solution over antibiotic irrigant or saline alone in removing Staphylococcus epidermidis from metallic surfaces. The use of a soap solution for irrigation seems to improve the removal of some bacteria from some surfaces in this experimental model and may represent a better type of irrigation additive. 相似文献
4.
5.
6.
7.
8.
Allergic autoimmune reaction after exposure to heavy metals such as mercury may play a causal role in autism, a developmental disorder of the central nervous system. As metallothionein (MT) is the primary metal-detoxifying protein in the body, we conducted a study of the MT protein and antibodies to metallothionein (anti-MT) in normal and autistic children whose exposure to mercury was only from thimerosal-containing vaccines. Laboratory analysis by immunoassays revealed that the serum level of MT did not significantly differ between normal and autistic children. Furthermore, autistic children harboured normal levels of anti-MT, including antibodies to isoform MT-I (anti-MT-I) and MT-II (anti-MT-II), without any significant difference between normal and autistic children. Our findings indicate that because autistic children have a normal profile of MT and anti-MT, the mercury-induced autoimmunity to MT may not be implicated in the pathogenesis of autism. 相似文献
9.
Sharon Craven Lori Dewar Xianjun Yang Jeff Ginsberg Frederick Ofosu 《Blood coagulation & fibrinolysis》2007,18(3):219-225
Up to 20% of patients develop venographically proven deep-vein thrombosis after elective orthopedic surgery even under the cover of heparin or low molecular weight heparin. The extent to which the chronic inflammation of osteoarthritis requiring elective orthopedic surgery alters in-vivo coagulation and whether any specific alteration influences the development of postoperative thrombosis are unknown. This study compared the concentrations of activated factor VII (FVIIa), tissue factor pathway inhibitor (TFPI), activated factor X (FXa)-TFPI, thrombin-antithrombin, and prothrombin fragment 1+2 (F1+2) in plasmas of 535 healthy individuals (ages 17-76) with those in the preoperative plasmas of 306 arthritis patients (ages 30-92) scheduled for elective knee or hip replacement surgery. C-reactive protein was also measured in the plasmas of approximately 15% of the participants. Age-adjusted concentrations of FVIIa, F1+2, and C-reactive protein were higher in patients than controls, while the concentrations of thrombin-antithrombin, TFPI and FXa-TFPI were similar. Chronic inflammation in the patients was thus associated with increased coagulation in vivo. Without compensatory increases in the concentrations of TFPI (natural inhibitor of prothrombinase), the elevated concentrations of FVIIa in the preoperative plasmas and the trauma associated with surgery may enhance the risk for developing postoperative deep-vein thrombosis. 相似文献
10.
Miriam Stewart Linda Reutter Edward Makwarimba Irving Rootman Deanna Williamson Kim Raine Doug Wilson Janet Fast Rhonda Love Sharon McFall Deana Shorten Nicole Letourneau Karen Hayward Jeff Masuda William Rutakumwa 《Revue canadienne de recherche en sciences infirmières》2005,37(3):104-131
Poverty influences health status, life expectancy, health behaviours, and use of health services. This study examined factors influencing the use of health-related services by people living in poverty. In the first phase, 199 impoverished users of health-related services in 2 large Canadian cities were interviewed by their peers. In the second phase, group interviews with people living in poverty (n = 52) were conducted. Data were analyzed using thematic content analysis. Diverse health-related services were used to meet basic and health needs, to maintain human contact, and to cope with life's challenges. Use of services depended on proximity, affordability, convenience, information, and providers' attitudes and behaviours. Use was impeded by inequities based on income status. To promote the health of people living in poverty, nurses and other health professionals can enhance the accessibility and quality of services, improve their interactions with people living in poverty, provide information about available programs, offer coordinated community-based services, collaborate with other sectors, and advocate for more equitable services and policies. 相似文献