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Cranial sutures and craniometric points detected on MRI 总被引:2,自引:0,他引:2
Cotton F Rozzi FR Vallee B Pachai C Hermier M Guihard-Costa AM Froment JC 《Surgical and radiologic anatomy : SRA》2005,27(1):64-70
The main goal of the study was to determine on MRI the cranial sutures, the craniometric points and craniometric measurements, and to correlate these results with classical anthropometric measurements. For this purpose, we reviewed 150 cerebral MRI examinations considered as normal (Caucasian population aged 2049 years). For each examination we individualized 11 craniometric landmarks (Glabella, Bregma, Lambda, Opisthocranion, Opisthion, Basion, Inion, Porion, Infra-orbital, Eurion) and three measurements. Measurements were also calculated independently on 498 dry crania (Microscribe 3-DX digitizer). To validate the MRI procedure, we measured four dry crania by MRI and with compass or digital caliper gauges. Cranial sutures always appeared without signal (black), whatever the MRI sequence used, and they are better visualized with a 5 mm slice thickness (compact bone overlapping). Slice dynamic analysis and multiplanar reformatting allowed the detection of all craniometric points, some of these being more difficult to detect than others (Porion, Infra-orbital). The measurements determined by these points were as follows: VertexBasion height=135.66±6.56 mm; EurionEurion width=141.17±5.19 mm; GlabellaOpisthocranion length=181.94±6.40 mm. On the midline T1-weighted sagittal image, all median craniometric landmarks can be individualized and the GlabellaOpisthocranion length, VertexBasion height and parenchyma indices can be calculated. Craniometric points and measurements between these points can be estimated with a standard cerebral MRI examination, with results that are similar to anthropometric data. 相似文献
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Nayef Chahin Miheret S. Yitayew Alicia Richards Brielle Forsthoffer Jie Xu Karen D. Hendricks-Muoz 《Nutrients》2022,14(11)
Little information exists about the plasma target nutritional needs of the >15 million premature infants <37 weeks gestation. Investigating ascorbic acid’s (AscA) role in infant health, our study details the relationship of infant characteristics and maternal health on infant plasma AscA level (pAscA) during postnatal development. Furthermore, we determined pAscA influence during the first week of life (EpAscA) with later infant morbidities. We hypothesize that pAscA is influenced by gestational organ immaturity, as well as maternal factors, with EpAscA associated with greater morbidity risk. We conducted a prospective longitudinal observational study of pAscA, demographics and hospital course detailed in infants ≤34 weeks. Sixty-three subjects were included, with >200 urine and plasma data points analyzed. Maternal smoking, exposure to magnesium sulfate (MgSO4) and advancing gestational and postnatal age were associated with lower pAscA. Non-white infants and those ≤30 weeks that developed bronchopulmonary dysplasia or retinopathy of prematurity had lower pAscA. Prenatal smoking, MgSO4, birth gestational age and race negatively influence pAscA. These results show prenatal and postnatal developmental factors influencing initial pAscA and metabolism, potentially setting the stage for organ health and risk for disease. Assessment of dietary targets may need adjustment in this population. 相似文献
5.
Brigitte Fatton Peter L. Dwyer Chahin Achtari P. K. Tan 《International urogynecology journal》2009,20(4):427-434
Introduction and hypothesis The objective of this study is to assess anatomical and functional results of the extraperitoneal uterosacral ligament suspension
(USL) in women with post-hysterectomy vaginal vault prolapse.
Methods One hundred and twenty-three consecutive women were included. Concurrent procedures were anterior colporraphy with fascial
repair (20%) and mesh reinforcement (49%), posterior colporraphy with fascial repair (38%) and mesh reinforcement (56%) and
a sling procedure (29%). Women were assessed using Baden and Walker and pelvic organ prolapse quantification classification
pre- and post-operatively.
Results One hundred and ten patients (89%) were available for follow-up. Mean follow-up was 2 years. Objective success rate regarding
the vaginal cuff is 95.4%. Global anatomical success rate was 85.5%. Urinary, coital and bowel symptoms were improved following
surgery. Mesh exposure rate was 19.3%, with all cases managed conservatively or with minor interventions.
Conclusion Bilateral extraperitoneal USL is an effective operation to restore apical support with low morbidity, which avoids potential
risks associated with opening the peritoneal cavity. 相似文献
6.
B. A. O’ Reilly M. Fynes C. Achtari R. Hiscock E. Thomas C. Murray P. L. Dwyer 《International urogynecology journal》2008,19(4):497-502
Overactive bladder (OAB) is a prevalent condition with 16% of adults having one or more symptoms that significantly affect
quality of life. Transcutaneous electrical nerve stimulation and neuromodulators have had success in treating OAB but are
expensive, invasive, and sometimes cumbersome. We developed an alternative neuromodulatory technique that involves electromagnetic
stimulation of the sacral nerve roots with a portable electromagnetic device to produce trans-sacral stimulation of the S3
and S4 sacral nerve roots. The aim of this study was to evaluate the impact of this device on OAB symptoms in women with a
prospectively randomised double-blind controlled study. Following a power analysis, women with symptoms of OAB were prospectively
recruited with ethical approval for randomisation to an active treatment (n = 33) or placebo group (n = 30) in a double-blind trial. The patient, at home, used the belt device daily for 20 min over 12 weeks. Outcome measures
included a 3-day voiding diary, 1 h pad test, visual analogue score (VAS) for symptom impact (0–100%), Kings Health Questionnaire
(KHQ) and Australian Quality of Life questionnaire (AQOL) at baseline, 6 and 12 weeks. Overall, no difference was found between
groups for any of the research questions. Specifically, we were unable to demonstrate any difference between the active and
sham device groups in frequency, nocturia, urinary leakage, or quality of life, nor was there any evidence of a placebo effect.
The quality of the data was high with the number of missing observations (especially for disease specific KHQ and general
AQOL) being few. This attempt to promote trans-sacral electromagnetic neuromodulation with a specially created device was
ineffective on the symptoms of OAB. 相似文献
7.
Eric M. L. Williamson Salim Chahin Joseph R. Berger 《Current neurology and neuroscience reports》2016,16(4):36
Vaccinations help prevent communicable disease. To be valuable, a vaccine’s ability to prevent disease must exceed the risk of adverse effects from administration. Many vaccines present no risk of infection as they are comprised of killed or non-infectious components while other vaccines consist of live attenuated microorganisms which carry a potential risk of infection—particularly, in patients with compromised immunity. There are several unique considerations with respect to vaccination in the multiple sclerosis (MS) population. First, there has been concern that vaccination may trigger or aggravate the disease. Second, disease-modifying therapies (DMTs) employed in the treatment of MS may increase the risk of infectious complications from vaccines or alter their efficacy. Lastly, in some cases, vaccination strategies may be part of the treatment paradigm in attempts to avoid complications of therapy. 相似文献
8.
We compared serum creatine kinase (CK) levels between spinobulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS) and reviewed available histochemical studies of frozen sections of muscle biopsies. CK levels and the frequency of patients with elevated CK levels were significantly higher in the SBMA group when compared with the ALS group. CK levels occasionally approached values up to 8 times the upper limit of normal in the SBMA group. In addition to the chronic neurogenic changes in the muscle biopsy, all SBMA patients showed one or more myopathic changes. Increased numbers of markedly hypertrophic fibers were consistently seen in all patients. It is not clear whether the elevated CK level is directly related to the increased number of hypertrophic fibers or to other myopathic features. Based on these findings, we recommend genetic testing for SBMA in cases of male patients with motor neuron disease who present with a significantly elevated serum creatine kinase level, even when other characteristic clinical features of SBMA are absent. Muscle Nerve 40: 126–129, 2009 相似文献
9.
O'Sullivan M Jouvent E Saemann PG Mangin JF Viswanathan A Gschwendtner A Bracoud L Pachai C Chabriat H Dichgans M 《NeuroImage》2008,43(2):312-320
Measurement of brain atrophy has been proposed as a surrogate marker in MS and degenerative dementias. Although cerebral small vessel disease predominantly affects white and subcortical grey matter, recent data suggest that whole brain atrophy is also a good indicator of clinical and cognitive status in this disease. Automated methods to measure atrophy are available that are accurate and reproducible in disease-free brains. However, optimal methods in small vessel disease have not been established and the impact of ischaemic lesions on different techniques has not been explored systematically. In this study, three contrasting techniques -- Statistical Parametric Mapping 5 (SPM5), SIENAX and BrainVisa -- were applied to measure cross-sectional atrophy (brain parenchymal fraction or BPF) in a large (n=143) two-centre cohort of patients with CADASIL, a genetic model of small vessel disease. All three techniques showed similar sensitivity to trends in BPF associated with age and lesion load. No single technique was particularly vulnerable to error as a result of lesions. Provided major errors in registration were excluded by visual inspection, manual correction of segmentations had a negligible impact with mean errors of 0.41% for SIENAX and 0.46% for BrainVisa. BPF correlated strongly with global cognitive function and physical disability, independent of the technique used. Correlation coefficients with the Minimental State Examination score were: BrainVisa 0.58, SIENAX 0.58, SPM5 0.60 (for all, p<0.001). These results suggest that all three methods can be applied reliably in patients with ischaemic lesions. Choice of analysis approach for this kind of clinical question will be determined by factors other than their robustness and precision, such as a desire to explore subtle localised changes using extensions of these processing tools. 相似文献
10.
The agonistic and antagonistic properties of nalbuphine were examined in 80 surgical patients after anaesthesia consisting essentially of flunitrazepam/enflurane or flunitrazepam/fentanyl. After the operation the intubated and still unconscious patients were breathing either N2O/O2/enflurane 0.4 Vol.% or N2O/O2 (FIO2 0.33). The mean fentanyl requirement during operation was 0.55 microgram/kg body weight/10 min anaesthesia. The respiratory minute volumes (RMV) were similar in all groups and ranged between 77-89% of the calculated normal value. The respiratory rate was 18-23/min in the enflurane groups and 11-12/min in the fentanyl groups. After reaching a circulatory and respiratory steady state, nalbuphine was administered i.v. in the doses of 2.5, 5, 10 or 20 mg. In the enflurane groups nalbuphine produced a pure depressant effect on respiratory parameters. The RMV decreased by 27 +/- 3%, the calculated alveolar ventilation by 20-24% and the breathing rate by 6 breath/min. A new steady state was reached within 10 min. The well-known ceiling effect was observed. In contrast to the observations in awake patients the maximum depressant effect was already reached after a dose of only 5 mg nalbuphine. Arterial blood pressure decreased by 4-5 mmHg and heart rate by 5 beats/min. After fentanyl, however, nalbuphine in all doses exhibited a stimulating effect on respiration and circulation. A steady state was reached after 10 min as well. A maximum effect on alveolar ventilation (+ 39 +/- 8%) was obtained after 5 mg nalbuphine and did not increase further with increasing doses. The effects on RMV and on respiratory rate were dose dependent. Arterial blood pressure increased slightly as did heart rate.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献