全文获取类型
收费全文 | 5053篇 |
免费 | 334篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 32篇 |
儿科学 | 69篇 |
妇产科学 | 94篇 |
基础医学 | 708篇 |
口腔科学 | 88篇 |
临床医学 | 557篇 |
内科学 | 1000篇 |
皮肤病学 | 68篇 |
神经病学 | 363篇 |
特种医学 | 220篇 |
外科学 | 863篇 |
综合类 | 65篇 |
一般理论 | 5篇 |
预防医学 | 388篇 |
眼科学 | 98篇 |
药学 | 324篇 |
中国医学 | 4篇 |
肿瘤学 | 451篇 |
出版年
2024年 | 8篇 |
2023年 | 56篇 |
2022年 | 81篇 |
2021年 | 181篇 |
2020年 | 75篇 |
2019年 | 156篇 |
2018年 | 169篇 |
2017年 | 111篇 |
2016年 | 132篇 |
2015年 | 143篇 |
2014年 | 236篇 |
2013年 | 272篇 |
2012年 | 411篇 |
2011年 | 419篇 |
2010年 | 240篇 |
2009年 | 193篇 |
2008年 | 306篇 |
2007年 | 323篇 |
2006年 | 261篇 |
2005年 | 275篇 |
2004年 | 245篇 |
2003年 | 251篇 |
2002年 | 218篇 |
2001年 | 61篇 |
2000年 | 69篇 |
1999年 | 39篇 |
1998年 | 39篇 |
1997年 | 24篇 |
1996年 | 20篇 |
1995年 | 18篇 |
1993年 | 10篇 |
1992年 | 27篇 |
1991年 | 23篇 |
1990年 | 26篇 |
1989年 | 18篇 |
1988年 | 19篇 |
1987年 | 14篇 |
1986年 | 17篇 |
1985年 | 17篇 |
1983年 | 11篇 |
1982年 | 9篇 |
1979年 | 18篇 |
1978年 | 13篇 |
1977年 | 11篇 |
1976年 | 14篇 |
1975年 | 10篇 |
1974年 | 16篇 |
1973年 | 11篇 |
1972年 | 10篇 |
1967年 | 7篇 |
排序方式: 共有5397条查询结果,搜索用时 0 毫秒
1.
2.
3.
Denise M Connor Shawn Binkley Neil O Fishman Leanne B Gasink Darren Linkin Ebbing Lautenbach 《Infection control and hospital epidemiology》2007,28(12):1408-1410
We examined the possible unintended consequences of a 72-hour automatic order to discontinue vancomycin therapy in an antimicrobial stewardship program (ASP). Of 120 patients, 11 had vancomycin therapy discontinued at 72 hours without a call to the ASP, and 7 experienced a treatment interruption of 6-36 hours. All discontinuation of therapy was considered appropriate, and the 7 treatment interruptions did not have clear clinical consequences. Only one-third of patients had ASP stickers that warned of impending discontinuation of vancomycin therapy placed appropriately in the medical record. 相似文献
4.
Darren S Parsons David A Reaveley Darrell V Pavitt Madhukar Misra Edwina A Brown 《Nephrology, dialysis, transplantation》2003,18(9):1848-1853
BACKGROUND: Studies have reported an increase in median Lipoprotein (Lp) (a) in patients with high molecular weight (HMW) apolipoprotein (apo) (a) isoforms and renal impairment. Some studies identify Lp (a) levels as a risk factor for vascular disease in renal failure whilst others have demonstrated an association with apo (a) isoform type and vascular disease. METHODS: A total of 239 patients at end-stage renal failure (ESRF) were studied prior to the initiation of dialysis. Blood was taken for Lp (a) levels and apo (a) isoforms. Clinical vascular disease (CVD) was assessed on the basis of clinical history and Rose questionnaire. The control group for Lp (a) levels consisted of 228 healthy volunteers. RESULTS: Despite a higher median Lp (a) level in those with HMW isoforms, 30% of patients had Lp (a) levels <10 mg/dl. Overall, 49% patients were identified as having CVD. Diabetes, smoking history and Lp (a) levels were significantly associated with CVD in logistic regression analysis, although when patients with low molecular weight (LMW) and HMW isoforms were analysed separately, Lp (a) levels were not significantly associated with CVD in those with LMW isoforms. The rates of CVD in those with HMW isoform and low Lp (a) levels were significantly lower than those with HMW isoforms and elevated Lp (a) levels, 34 vs 57% (P < 0.01). CONCLUSIONS: Although median Lp (a) levels in those patients at ESRF with HMW isoforms are higher than controls, in a third of such patients Lp (a) levels remain relatively low. These patients have lower rates of CVD than those with high levels of Lp (a). 相似文献
5.
Recently, anatomic or double-bundle reconstruction of the anterior cruciate ligament (ACL) has been presented in an effort to more accurately restore the native anatomy. These techniques create 2 tunnels in both the femur and tibia to reproduce the bundles of the ACL. However, the increased number of tunnels, particularly on the femoral side, has raised some concerns among authors and surgeons. We describe a technique to reconstruct the 2 distinct bundles of the ACL by using a single femoral tunnel and 2 tibial tunnels, the “hybrid” ACL reconstruction. The femoral tunnel is drilled through an anteromedial arthroscopy portal, which allows placement in a more anatomic position. Fixation in the femur is achieved with a novel device that separates a soft-tissue graft into 2 independently functioning bundles. Once fixed in the femur, the anteromedial and posterolateral bundles of the graft are passed through respective tunnels at the anatomic footprint on the tibia. These bundles are independently tensioned, which creates a reconconstruction that is similar to the native ACL. The technique presented provides surgeons with an alternative to other double-bundle techniques involving 4 tunnels. 相似文献
6.
J. Randolph Swartz Ira M. Lesser Kyle B. Boone Bruce L. Miller Ismael Mena 《International journal of geriatric psychiatry》1995,10(6):437-446
Global and regional cerebral blood flow (CBF) were evaluated with single photon emission computerized tomography (SPECT) utilizing both 133Xenon (133Xe) (47 subjects, 47–82 years old) and 99Tc-hexamethylpropyleneamine oxime (99Tc-HMPAO) (27 subjects, 47–80 years old). The 133Xe results showed: among total subjects, no age-related decline in global CBF, but a significant regional decline in the occipital lobe (p < 0.05); among men, significant age-related declines in global, frontal, temporal, occipital and right hemisphere CBF (all p < 0.05); among women, no age-related decline in global or regional CBF. The 99Tc-HMPAO results showed no age-related decline in either global or regional perfusion among total subjects, men or women. These results suggest that age-related global and regional (including frontal lobe) CBF declines do not occur in healthy control subjects after the age of 45 years. However, gender differences in age-related CBF changes warrant further study. 相似文献
7.
8.
J. M. Greally L. Y. Boone S. G. Lenkey S. L. Wenger M. W. Steele 《American journal of medical genetics. Part A》1992,44(3):334-339
A child with manifestations of acrogeria and metageria, two “premature aging” syndromes, is presented. Because of his indistinct phenotype and because the question has been previously raised as to whether these conditions are separate, we propose the designation of acrometageria to describe this phenotypic continuum. As there is much in common clinically between acrometageria and the syndrome of type III procollagen deficiency (Ehlers-Danlos type IV), it might be presumed that a similar pathogenesis for acrometageria exists. This possibility has been tested previously, without demonstrating specific quantitative or qualitative deficits, but with some indirect evidence that collagen metabolism is deranged in these patients. One such crude indicator is the elevation of urinary hyaluronic acid levels, demonstrated in our patient and also observed in the phenotypically distinct Werner and Hutchinson-Gilford premature aging syndromes. On one hand, it could be argued that this supports the concept that premature aging syndromes exist as a biological continuum. On the other hand, it is equally valid to argue that syndromes of premature aging are so described merely because they include recognizable changes of normal aging and that the demonstration of an underlying mutation in a collagen gene, for example, invalidates their study as models of accelerated normal aging. © Wiley-Liss, Inc. 相似文献
9.
Radiation levels near an imaging chain commonly used in angiography were measured with both a 100- and a 200-mm-thick scatter phantom. The scatter was measured in lines parallel in space to the central ray of the x-ray beam, at lateral distances of 300, 500, and 800 mm. The effects of fluoroscopic kilovoltage and image intensifier magnification mode were also measured. The results indicate that the highest scattered radiation levels occur near the surface of the patient where the x-ray beam enters. Exposure rates were measured in both anteroposterior (AP) and posteroanterior (PA) geometries on a U-arm system. In PA geometry, the highest radiation levels occur below the angiographer's waist, an area well protected by the lead apron. The AP geometry increases the exposure rate to the neck, head, and upper extremities, areas where apron shielding is less effective. 相似文献
10.
D E Boone 《Journal of clinical psychology》1991,47(2):271-276
The relative performance of two Wechsler Adult Intelligence Scale-Revised (WAIS-R) short forms, the Satz-Mogel item reduction technique (Adams, Smigielski, & Jenkins, 1984; Satz & Mogel, 1962) and the Silverstein (1982) subtest-reduction technique, was examined for a group of psychiatric inpatients (N = 75). The two short forms were evaluated on several criteria, including their ability to predict the Full Scale IQ (FSIQ) using regression analysis, their reliability, and their total administration time. The standard error of estimates obtained in predicting the FSIQ were comparable for both short forms and resulted in a +/- 7 confidence interval to achieve 90% accuracy. 相似文献