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1.
Changes in plasma amino acids, 24-h nitrogen balances, and resting metabolic expenditures (RMEs) were measured in 10 geriatric patients (aged 70-92 y) with hip fracture 1 d after surgical fixation during both a 24-h fasting state and while receiving total peripheral parenteral nutrition (TPPN) for 24 h at 1.5 g amino acids.kg-1.d-1 and 29-30 kcal.kg-1.d-1 and compared with 19 healthy volunteer subjects (aged 70-84 y). RME and 24-h urinary nitrogen losses were also elevated in the trauma patients during both fasting and TPPN. Positive nitrogen balances were evident in both groups during TPPN. Plasma total amino acid concentration was significantly lower in the trauma patients because of lower plasma concentrations of the nonessential amino acids. Phenylalanine and methionine concentrations were significantly higher and lysine lower in the trauma group. In addition, evaluation of the essential amino acid ratios after fasting and TPPN reveal that there are no limiting amino acids during TPPN.  相似文献   
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Pain during sexual activity and ejaculation are the unspoken long-term complications of groin hernia repair. Laparoscopic surgical techniques are associated with decreased post-operative pain and earlier return to daily activities, but its effect on these complications is unclear. This study aims to investigate the effect of transabdominal preperitoneal repair (TAPP) on de-novo pain during sexual intercourse and ejaculation and to compare with open repair. For this reason, two groups were determined according to the surgical technique: the Lichtenstein repair and the TAPP groups and a questionnaire was sent to the patients a minimum of 6 months following the surgery. A total of 317 patients included, as 115 in TAPP and 202 in Lichtenstein repair group. No significant difference was observed concerning pre-operative pain during sexual activity and ejaculation in both groups (p = .75, p = .56). Following the surgery, the number of patients experiencing painful sexual activity was significantly higher in the Lichtenstein repair group compared to the TAPP group (19.3% vs. 11.3%, respectively, p = .03). The post-operative painful ejaculation rate was also significantly lower for the TAPP group (p = .04). The lower rates of post-operative dysejaculation and pain during sexual activity can be achieved with the advantage of laparoscopic surgery.  相似文献   
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1.  Naja flava venom heated to 100° C for 15 minutes interferes with intracerebrally inducedBrunhilde andLansing poliomyelitis infection in rhesus monkeys when the blockading agent is administered subcutaneously 24 hours after infection.
2.  It is suggested that this interference mechanism is based on the direct action of the heated venom on motoneurons, as evidenced by histopathologic changes in the spinal cords of normal rhesus monkeys injected subcutaneously with the venom.
3.  Similar histopathologic changes are seen when large doses ofNaja flava toxoid are injected subcutaneously into normal rhesus monkeys.
4.  An attempt has been made to extend the interpretation of the neurotoxoid and neurotoxin interference mechanism in poliomyelitis by correlating enzymatic studies of other workers with cobra venom and with chromatolytic cells refractory to poliomyelitis infection.
1.  Wird dasNaja-flava-Gift durch 15 Minuten auf 100° C erhitzt, dann hemmt es die intracerebral eingebrachteBrunhilde- undLansing-Poliomyelitis-Infektion bei Rhesusaffen, wenn das blockierende Agens 24 Stunden nach der Infektion subkutan zugeführt wird.
2.  Es wird angenommen, daß dieser Hemmungsmechanismus auf der direkten Einwirkung des erhitzten Giftes auf die Motoneurone beruht, was durch histopathologische Veränderungen im Rückenmark normaler Rhesusaffen, denen das Gift subkutan injiziert wurde, bewiesen wird.
3.  Ähnliche histopathologische Veränderungen werden bemerkt, wenn starke Dosen desNaja-flava-Toxoids normalen Rhesusaffen subkutan injiziert werden.
4.  Es wurde der Versuch gemacht, die Erklärung des Neurotoxoid- und Neurotoxin-Hemmungsmechanismus bei der Poliomyelitis durch die Vergleichung enzymatischer Studien anderer Forscher am Kobra-Gift und an chromatolytischen Zellen, die der Poliomyelitis-Infektion Widerstand leisten, zu erweitern.

With 7 Figures.  相似文献   
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BACKGROUND: Direct insertion of the trocar is an alternative method to Veress needle insertion for the creation of pneumoperitoneum. The safety of direct disposable shielded trocar insertion for the creation of pneumoperitoneum was assessed by comparing with Veress needle insertion during laparoscopic cholecystectomy (LC). METHODS: One thousand five hundred patients undergoing LC with pneumoperitoneum were included in this study. In 470 patients the Veress needle insertion technique was used, and in 1,030 patients direct trocar insertion technique was used. Patients having indications for open trocar insertion were excluded from the study. RESULTS: Complication rate was significantly higher in the Veress needle group (14% versus 0.9%; P <0.01), and the two major complications, gastric perforation and iliac artery laceration, were also encountered in this group. CONCLUSIONS: Our results suggest that with a lower complication rate, direct insertion of the disposable trocar is a safe alternative to Veress needle insertion technique for the creation of pneumoperitoneum. Such an approach has further advantages such as less cost/instrumentation and rapid creation of pneumoperitoneum.  相似文献   
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Hibernomas are rare soft tissue tumors of brown fat differentiation. A case of a large axillary hibernoma, along with a review of its pathology, is presented. This tumor matches the largest hibernoma in the literature and is the largest in an axillary site.  相似文献   
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