全文获取类型
收费全文 | 763篇 |
免费 | 47篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 19篇 |
妇产科学 | 16篇 |
基础医学 | 143篇 |
口腔科学 | 22篇 |
临床医学 | 85篇 |
内科学 | 112篇 |
皮肤病学 | 13篇 |
神经病学 | 131篇 |
特种医学 | 13篇 |
外科学 | 64篇 |
综合类 | 6篇 |
一般理论 | 2篇 |
预防医学 | 67篇 |
眼科学 | 13篇 |
药学 | 52篇 |
中国医学 | 3篇 |
肿瘤学 | 49篇 |
出版年
2022年 | 12篇 |
2021年 | 25篇 |
2020年 | 16篇 |
2019年 | 15篇 |
2018年 | 18篇 |
2017年 | 8篇 |
2016年 | 12篇 |
2015年 | 14篇 |
2014年 | 27篇 |
2013年 | 25篇 |
2012年 | 50篇 |
2011年 | 47篇 |
2010年 | 31篇 |
2009年 | 26篇 |
2008年 | 28篇 |
2007年 | 37篇 |
2006年 | 50篇 |
2005年 | 31篇 |
2004年 | 33篇 |
2003年 | 29篇 |
2002年 | 32篇 |
2001年 | 20篇 |
2000年 | 12篇 |
1999年 | 13篇 |
1998年 | 6篇 |
1997年 | 8篇 |
1995年 | 4篇 |
1994年 | 6篇 |
1993年 | 4篇 |
1992年 | 4篇 |
1991年 | 4篇 |
1990年 | 5篇 |
1989年 | 5篇 |
1988年 | 10篇 |
1987年 | 11篇 |
1986年 | 5篇 |
1985年 | 11篇 |
1984年 | 11篇 |
1983年 | 9篇 |
1982年 | 7篇 |
1981年 | 4篇 |
1980年 | 4篇 |
1979年 | 4篇 |
1978年 | 5篇 |
1977年 | 7篇 |
1976年 | 6篇 |
1973年 | 7篇 |
1972年 | 4篇 |
1970年 | 4篇 |
1969年 | 4篇 |
排序方式: 共有814条查询结果,搜索用时 15 毫秒
1.
Rolando Barbucci Mario Casolaro Mila Nocentini Gianna Reginato Paolo Ferruti 《Macromolecular chemistry and physics.》1986,187(8):1953-1962
Two linear vinyl polymers carrying amido and primary amino groups in the side chains were synthesized and characterized. Their behaviour in aqueous solution was investigated by potentiometric, viscometric and calorimetric techniques. In both cases, the basicity constants show a linear dependence on the degree of protonation α, while the enthalpy values of protonation do not. The thermodynamic results demonstrate the important role of hydrophobic interactions on the protonation process. 相似文献
2.
Immunoblotting of Creutzfeldt-Jakob disease prion proteins: host species-specific epitopes 总被引:9,自引:0,他引:9
Creutzfeldt-Jakob disease (CJD) is a rare dementia that is generally found in older people and is caused by unusual infectious pathogens or prions. Using rabbit antisera raised against hamster scrapie prion proteins (HaPrPSc), we identified by immunoblotting human CJD prion proteins (HuPrPCJD) in the brains of 14 patients dying of CJD. Extracts from 6 of the patients were transmitted to mice after prolonged incubation. The rabbit antisera raised against HaPrPSc also reacted with the mouse CJD prion proteins (MoPrPCJD) found in the brains of these experimentally infected mice. When mice were immunized with HuPrPCJD, they produced antibodies that reacted with HuPrPCJD but not with MoPrPCJD. Mice immunized with MoPrPCJD produced antibodies to neither murine nor human prion proteins. Our results provide evidence for host species-specific epitopes on prion proteins. The existence of such epitopes is consistent with the apparent lack of an immune response during prion infections and the finding that prion protein molecules are encoded by host genes. 相似文献
3.
N. Matamoros Florí J. Mila Llambi T. Español Boren S. Raga Borja G. Fontan Casariego 《Journal of clinical immunology》1997,17(4):333-339
The Spanish Registry for Primary Immunodeficiency Diseases (REDIP) was organized in 1993. One thousand sixty-nine cases of primary immunodeficiency diseases (PID) were registered in patients diagnosed between January 1980 and December 1995. PID diagnosis was made according to the World Health Organization criteria. The most frequent disorders were IgA deficiency (n = 394) and common variable immunodeficiency (n = 213), followed by severe combined immunodeficiency (n = 61), C1 inhibitor deficiency (n = 52), X-Iinked agammaglobulinemia (n = 49), IgG subclass deficiency (n = 48), and chronic granulomatous disease (n = 32). A comparative study between REDIP and data recently obtained from the European registry (ESID Report, 1995) revealed important differences between phagocytic disorders and complement deficiencies reported in both registries, 4.9 vs 8.7 and 6.0 vs 3.6, while percentages of predominantly antibody deficiencies and T cell and combined deficiencies concurred with those reported in the European registry, 69.3 vs 64.7 and 14.7 vs 20.2, respectively. The heterogeneous nature of the geographical distribution of cases submitted may indicate underdiagnosis of PID in some country areas; surprisingly, the interval between the onset of clinical symptoms and diagnosis was significant, even in immunodeficiency diseases, such as IgA deficiency, which are easy to diagnose. 相似文献
4.
5.
B. V. Helson K. N. Barber P. D. Kingsbury 《Archives of environmental contamination and toxicology》1994,27(1):107-114
Laboratory dose-response studies were conducted with four species of adult bees, Apis mellifera (workers), Andrena erythronii (females), Megachile rotundata (females), and Bombus terricola (workers), using six insecticides, permethrin, mexacarbate, aminocarb, fenitrothion, carbaryl, and trichlorfon. All insecticides were applied topically to the thorax of the bees as technical grade in an acetone carrier. Mortality was accumulated over 48 h, and probit analyses were conducted separately on data sets expressed in units of gAI (active ingredient)/g body weight and of gAI/bee. LD50 values with 95% confidence limits and slopes with standard errors are provided for each bee/insecticide combination in each data set. Relative toxicities, relative susceptibilities, and fresh body weights are also provided. The analysis in units of gAI/g body weight indicated that the insecticides were typically ranked in order of decreasing toxicity—permethrin, mexacarbate, aminocarb, fenitrothion, carbaryl, and trichlorfon. Likewise, the bees ranked from the most to least susceptible in the order of A. mellifera, A. erythronii, M. rotundata and B. terricola. Trends within the data set for units of gAI/bee were less consistent. These data are discussed and compared with other published data on the toxicology of insecticides to bees and from the perspective of risk assessment. 相似文献
6.
Circular DNA resulting from recombination between V-(D)-J joining signals and switch repetitive sequences in mouse thymocytes 总被引:2,自引:0,他引:2
During the course of analyzing circular DNA in mouse thymocytes, novel recombinants were identified with immunoglobulin heavy chain joining gene and switch region probes. These circles represent excision products of recombination between the heptamer-nonamer motif for V-(D)-J joining and a repetitive sequence for class switching. The molecular mechanisms that generate "hybrid circles" are discussed. 相似文献
7.
8.
9.
Mila TEJAMAYA Wantanee PHANPRSIT Jiwon KIM Feng-Jen TSAI Go MUTO Derek MILLER Alex REGINALD Nelia GRANADILLOS Carmela CAPULE Marina Bt ZAINAL FARID Yu-wen LIN Jihoon PARK Ruey-Yu CHEN Kyong Hui LEE Jeongim PARK Haruo HASHIMOTO Haesong KWON Chungsik YOON Chantana PADUNGTOD Elsye As SAFIRA Dong-Uk PARK 《Industrial health》2022,60(6):589
The types of workplaces and occupations with coronavirus 2019 (COVID-19) clusters vary between countries and periods. We aimed to characterize major occupational groups with mass outbreaks of COVID-19 infections in several Asia-Pacific countries. Data on the major occupations or workplaces reporting COVID-19 cases in workplaces from January 2020 to July 2021 was collected from industrial hygiene professionals in nine countries. The proportion of workers accounted for 39.1 to 56.6% of the population in each country. The number of workers covered in the national statistics varies among nations based on their definition of a worker. None of the countries examined here have systematically collected occupational data on COVID-19 illnesses and deaths classified by type of industry, occupation, or job. Most countries experienced COVID-19 clusters among health and social care workers (HSCW) in hospitals or long-term care facilities. The types of occupations or workplaces with virus clusters in some participating countries included prisons, call centers, workplaces employing immigrants, garment facilities, grocery stores, and the military, which differed among countries, except for a few common occupations such as HSCW and those populated by immigrants. Further study is necessary in order to seek ways to control infection risks, including revisions to industrial-health-related laws. 相似文献
10.