全文获取类型
收费全文 | 1320篇 |
免费 | 64篇 |
国内免费 | 56篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 72篇 |
妇产科学 | 9篇 |
基础医学 | 149篇 |
口腔科学 | 24篇 |
临床医学 | 150篇 |
内科学 | 315篇 |
皮肤病学 | 65篇 |
神经病学 | 55篇 |
特种医学 | 301篇 |
外科学 | 62篇 |
综合类 | 23篇 |
预防医学 | 57篇 |
眼科学 | 15篇 |
药学 | 83篇 |
中国医学 | 2篇 |
肿瘤学 | 56篇 |
出版年
2023年 | 5篇 |
2022年 | 5篇 |
2021年 | 11篇 |
2020年 | 9篇 |
2019年 | 12篇 |
2018年 | 27篇 |
2017年 | 6篇 |
2016年 | 10篇 |
2015年 | 15篇 |
2014年 | 17篇 |
2013年 | 43篇 |
2012年 | 30篇 |
2011年 | 26篇 |
2010年 | 40篇 |
2009年 | 64篇 |
2008年 | 26篇 |
2007年 | 60篇 |
2006年 | 25篇 |
2005年 | 26篇 |
2004年 | 24篇 |
2003年 | 23篇 |
2002年 | 25篇 |
2001年 | 21篇 |
2000年 | 24篇 |
1999年 | 22篇 |
1998年 | 75篇 |
1997年 | 86篇 |
1996年 | 103篇 |
1995年 | 62篇 |
1994年 | 58篇 |
1993年 | 53篇 |
1992年 | 20篇 |
1991年 | 18篇 |
1990年 | 27篇 |
1989年 | 40篇 |
1988年 | 43篇 |
1987年 | 45篇 |
1986年 | 50篇 |
1985年 | 42篇 |
1984年 | 11篇 |
1983年 | 14篇 |
1982年 | 13篇 |
1981年 | 10篇 |
1980年 | 11篇 |
1979年 | 8篇 |
1978年 | 13篇 |
1977年 | 10篇 |
1976年 | 13篇 |
1975年 | 13篇 |
1973年 | 2篇 |
排序方式: 共有1440条查询结果,搜索用时 0 毫秒
1.
2.
The study concerned the effects of acute and chronic clomipramine administration to male rats on exploratory activity in a novel environment (hole-board) and on immobility in the forced swimming test. Acute clomipramine administration did not alter either exploratory activity on a hole-board as measured 3 or 20 h after drug administration, or immobility in the forced swimming test as measured 20 h after drug administration. Approximately 20 h after the last injection of clomipramine, the rats chronically treated with the drug showed reduced exploratory activity on the hole-board. In contrast, chronic clomipramine treatment significantly increased the activity in the forced swimming test. The effects of the drug on exploratory and forced swimming activities persisted for 14 days after the cessation of clomipramine administration. These data indicate that chronic clomipramine administration exerted profound and long-lasting effects on central nervous system function. The long-lasting action of the drug on behaviour in the forced swimming test might explain the long-term beneficial effect of antidepressant drugs in counteracting behavioral depression. 相似文献
3.
JC Sitek† M Loeb‡ JR Ronnevig¶ 《Journal of the European Academy of Dermatology and Venereology》2007,21(7):891-896
BACKGROUND: Since 1997, a number of trials have shown promising results in treating generalized vitiligo with narrowband ultraviolet B (UVB) both in adults and children. However, there is little knowledge concerning the duration and permanency of the treatment-induced repigmentation. OBJECTIVE: Our main objective was to perform a follow-up trial of successfully treated patients receiving narrowband UVB for generalized vitiligo. METHODS: We have investigated to what degree the treatment-induced repigmentation remains stable for up to 2 years post-treatment. We performed an initial open trial including 31 patients with generalized vitiligo. They received narrowband UVB thrice weekly for up to 12 months. Patients experiencing > 75% repigmentation were defined responders and were included in the follow-up trial. Responders were followed every 6 months for up to 2 years after cessation of treatment. We observed the pigmentation status and registered any changes indicating loss of pigmentation and relapse. RESULTS: Eleven of the 31 treated patients were included in the follow-up trial. Six patients had relapse and five patients had stable response 24 months after cessation of treatment. Four out of six relapses were within 6 months post-treatment. CONCLUSION: In our study population of 31 patients with generalized vitiligo, five patients (16%) experienced > 75% stable repigmentation 2 years after cessation of a treatment programme of up to 1 years narrowband UVB therapy. 相似文献
4.
Ultrasound (US) can be used to visualize vertebral segments, suggesting a quantitative means of studying vertebral column growth in utero and thus a means of detecting developmental abnormalities. US images of the lumbar spine were obtained in 128 clinically normal fetuses between the gestational age of 11 through 41 weeks. A large-aperture, dynamically focused US system capable of regional magnification was used. Average lumbar spacing was calculated from distance between centrums of at least four lumbar bodies. The average distance between lumbar centrums increased nearly linearly throughout the second and third trimesters (r2 = 0.98). Enhanced anatomic display implies new capabilities for recognizing developmental abnormalities antenatally. 相似文献
5.
6.
LN Weinberger MJ Zirwas JC English III 《Journal of the European Academy of Dermatology and Venereology》2007,21(2):156-162
Male genital oedema can be defined as swelling or the appearance of swelling of the scrotum and/or the penile shaft and prepuce. Despite the various causes of genital oedema reported in the published work, a concise approach to the evaluation and management has not been sufficiently addressed. 相似文献
7.
8.
9.
10.
Uroscopy in the 21st century: high-field NMR spectroscopy 总被引:1,自引:1,他引:0
Neild GH; Foxall PJ; Lindon JC; Holmes EC; Nicholson JK 《Nephrology, dialysis, transplantation》1997,12(3):404-417
From the experiments described, it can be seen that there are different
research approaches that can be taken and these are summarized in Table 1.
Whereas much scientific research is principally hypothesis led, there
remains, nevertheless, an important place for exploratory research. High
resolution NMR can measure, directly and simultaneously, a wide range of
endogenous metabolites in biological fluids and has the unique capability
of providing structural information on the metabolites detected. It has
proved to be a powerful research tool with which to study inherited
metabolic diseases, renal disease, drug metabolism, and toxicity, and can
be used to monitor the effects of drug therapy. For instance, by using a
library of experimental toxins one can map the metabolic profile of
site-specific nephron injury. With this approach in man one could
eventually take an unknown disease such as Balkan nephropathy and predict
the initial site of tubular injury, the mode of injury and therefore the
kind of toxin capable of producing that injury. NMR spectroscopic
techniques are still advancing rapidly, with ever increasing sensitivity
and sophistication of NMR pulse sequences to enhance structural elucidation
in complex mixtures. Given the advances in directly coupled HPLC-NMR and
even HPLC-NMR-mass spectroscopy it is likely that these technologies in
conjunction with pattern recognition will make major contribution to our
understanding of renal processes and provide new diagnostic insights in the
21st century.
相似文献