排序方式: 共有22条查询结果,搜索用时 15 毫秒
1.
Lichen planus pemphigoides. Is it a separate entity? 总被引:1,自引:0,他引:1
R. K. Joshi D. Natukorala A. Abanmi T.Al Awadi 《The British journal of dermatology》1994,130(4):537-538
2.
Sabry MA Farag TI Shaltout AA Zaki M Al-Mazidi Z Abulhassan SJ Al-Torki N Quishawi A Al Awadi SA 《Clinical genetics》1999,55(1):44-49
We describe 2 unrelated Bedouin girls who met the criteria for the diagnosis of Kenny-Caffey syndrome. The girls had some unusual features--microcephaly and psychomotor retardation--that distinguish the Kenny-Caffey syndrome profile in Arab children from the classical Kenny-Caffey syndrome phenotype characterized by macrocephaly and normal intelligence. The 2 girls did not harbor the 22q11 microdeletion (the hallmark of the DiGeorge cluster of diseases) that we previously reported in another Bedouin family with the Kenny-Caffey syndrome (Sabry et al. J Med Genet 1998: 35(1): 31-36). This indicates considerable genetic heterogeneity for this syndrome. We also review previously reported 44 Arab/Bedouin patients with the same profile of hypoparathyroidism, short stature, seizures, mental retardation and microcephaly. Our results suggest that these patients represent an Arab variant of Kenny-Caffey syndrome with characteristic microcephaly and psychomotor retardation. We suggest that all patients with Kenny-Caffey syndrome should be investigated for the 22q11 microdeletion. Other possible genetic causes for the Kenny-Caffey syndrome or its Arab variant include chromosome 10p abnormalities. 相似文献
3.
A multitude of local flaps has been suggested for lower extremity reconstruction. However, the gold standard for defect coverage remains free tissue transfer. In this regard, the scapular vascular axis is a well-established source of expendable skin, fascia, muscle, and bone for use in free flap reconstruction of defects requiring bone and soft tissue in complex 3-dimensional relationships.Composite bone and soft-tissue flaps derived from the subscapular vascular axis include the osteocutaneous scapular flap, the "latissimus/bone flap," and the thoracodorsal artery perforator-scapular osteocutaneous flap.Patient outcome following reconstruction of lower extremity defects with composite free flaps from the thoracodorsal system were analyzed. Here, we demonstrate the execution of technical refinements on free composite flap transfers based on the thoracodorsal vascular axis, thus resulting in a stepwise reduction of donor-site morbidity. 相似文献
4.
Nishith Kumar Jetley Ali H. Al Assiry Al Awadi S. Dawood Ragab H. Donkol 《Indian journal of pediatrics》2010,77(2):200-202
The patients were 8 and 9 years old respectively. Both were passengers in a vehicle and suffered multisystem injuries. Case
no.1 suffered a fractured occipital bone, lung contusions and a small pneumothorax in addition to the traumatic lung cysts
in the left lung. Case 2 sustained contused and lacerated liver and right lung cysts. CT examination showed cystic areas in
the lung which were diagnostic in case 2. In case 1 a traumatic rupture of diaphragm could not be ruled out and the patient
underwent an exploratory laparotomy to deal with the same. The lung cysts in both the patients were treated conservatively
and both showed resolution in repeat CT scans done at 6 months. 相似文献
5.
Analysis of neoadjuvant therapies in breast cancer with respect to pathological complete response,disease‐free survival and overall survival: 15 years follow‐up data from Kuwait 下载免费PDF全文
6.
Mahmoud H. Ayesh Khaled Jadalah Eiman Al Awadi Khaldoon Alawneh Basheer Khassawneh 《The Brazilian journal of infectious diseases》2013,17(6):629-632
ObjectiveEvaluate the association of Helicobacter pylori infection with anti-parietal cell antibodies (APCA) and anti-intrinsic factor antibodies (AIFA) and their impact on vitamin B12 serum level.Patients and methodsOne hundred patients (M/F: 43/57; age 46.5 ± 17.5 years) who underwent upper gastrointestinal endoscopy at King Abdullah University Hospital, Irbid, Jordan were enrolled in the study. The patients were grouped as H. pylori-infected (n = 81) or H. pylori negative (n = 19) by histopathological examination. Fasting serum vitamin B12 levels, anti-parietal cell antibodies and anti-intrinsic factor antibodies for patients and controls were determined.ResultsAnti-parietal cell antibodies and anti-intrinsic factor antibodies were positive in 9.9% and 18.5% of H. pylori-positive patients respectively. None of the H. pylori negative subjects had anti-parietal cell antibodies or anti-intrinsic factor antibodies. Serum vitamin B12 level was lower in the H. pylori-infected patients (275 ± 70.4 pg/mL) than in controls (322.9 ± 60.7 pg/mL; p < 0.05). H. pylori was positive in 94% of the low-vitamin B12 group compared with 64.6% of the normal-vitamin B12 group (p < 0.5).ConclusionPatients with H. pylori infection are more likely to have anti-parietal cell antibodies and anti-intrinsic factor antibodies. There was an association between H. pylori infection and lower vitamin B12 levels. H. pylori infection might be a significant factor in the pathogenesis of autoimmune gastritis. 相似文献
7.
8.
Hubert Mottl Viera Bajciova Jaroslav Nemec Salem Al Shemmari Shafika Al Awadi 《Pediatric hematology and oncology》2013,30(2):103-110
Non-Hodgkin lymphomas (NHL) in children are the second most common malignant tumors in Kuwait. Until 1995 the patients (pts) received institutional protocols. From October 1995 to September 2000 21 children with NHL were treated. Five children were treated by NHL BFM 90 protocol, 7 pts received NHL BFM 95 scheme, and 9 children underwent therapy abroad or according to different types of protocols. The results of a retrospective analysis of NHL BFM 95 protocol in Kuwait are reported. Seven patients diagnosed with NHL--group B: 3 children with Burkitt lymphoma (B-cell NHL) and group A: 4 children with lymphoblastic lymphoma (T-cell NHL)--were treated from October 1995 to September 2000 in the Kuwait Cancer Control Centre according to NHL BFM 95 protocol. Group B consisted of 2 girls and 1 boy; median age at diagnosis was 4 years 8 months, 2 pts classified as stage II and 1 pt as stage III. All patients were assigned to risk group R2. Median follow-up is 2 years 8 months. Group A included 1 girl and 3 boys; median age at diagnosis was 5 years 8 months, 1 pt classified as stage III and 3 pts as stage IV. All patients were assigned to IR group. Median follow-up is 3 years 6 months. In group B all 3 pts are in 1st CR; in group A 3 pts are in 1st CR and 1 pt having Li-Fraumani syndrome died after the 3rd relapse of disease during therapy. In both groups there was no toxic death, myelotoxicity WHO grade III-IV, hepatotoxicity WHO grade II-III. Treatment results of NHL BFM 95 study in our small group of patients are very optimistic. Six patients are in 1st CR and one died due to progression of disease. Despite the small group of patients, the results suggest that NHL BFM 95 protocol is highly effective and safe with regular supportive care. 相似文献
9.
Nishith Kumar Jetley Ali Hassan Al-Assiri Dawood Al Awadi 《Indian journal of pediatrics》2009,76(5):489-493
Objective Para esophageal hiatal hernia is a rare childhood condition and reported series have had scant number of children which makes
diagnosis a challenge. The authors sought to study the presentation and the outcome of treatment of congenital para esophageal
hernias (CPEH) over a period of 10 years from a single tertiary care hospital in Saudi Arabia.
Methods The records of 9 patients presenting between 1997 and 2007, were retrospectively analyzed for demographics, presenting features,
referral diagnoses, investigations, management including operative procedures, their outcome and follow-up.
Results Nine patients (3 males and 6 females) aged between 8 days to 34 months were seen. Respiratory distress (n=6), vomiting (n=5)
and frequent respiratory tract infections (n=3) were the most common presentations. Cyanosis (n=2), cough and excessive crying
were the other important symptoms. The referral diagnoses in these patients included congenital Bochdalek’s hernias, lung
abscess, bronchogenic cyst, pneumatocoele, bronchiolitis, and pneumonias which reflected a misinterpretation of their clinical
findings and chest X-rays. Seven of these patients had other associated congenital anomalies. Three had cardiovascular abnormalities
and 2 had lesions of the central nervous system. A pair of siblings had Marfan’s syndrome. All the patients had abnormal chest
C-rays and an UGS (upper GI series) proved to be diagnostic in 8 patients. The CT scans done in 4 patients corroborated the
findings of the UGS. A laparotomy was done on most patients (n=8) which comprised of reduction of the stomach, resection of
the hernial sac, tightening of the hiatus and a gastropexy or a gastrostomy. One patient, who underwent thoracotomy died of
surgical complications. Two others died of causes unrelated to the surgery. The remaining six operated patients have been
followed up for a median of 3.5 years and are doing well.
Conclusion CPEH is uncommon in children, presented with respiratory tract symptoms and vomiting, and may be associated with Martan’s
syndrome. It should be considered in the workup of a child with vomiting or frequent chest infections. Abnormal chest X-rays
may indicate the diagnosis and a subsequent UGS, is confirmatory. The present study found the aparotomya good approach for
repair of the wide hiatus. A gastropexy and a floppy fundoplication were added to prevent reherniation and post operative
reflux though given the small numbers it is not possible to determine the place of either of these procedures. CPEH may be
frequently associated with other congenital problems which may impact survival. 相似文献
10.