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Treatment outcomes and validation of the stopping rule for response to peginterferon in chronic hepatitis B: A Thai nationwide cohort study
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Phunchai Charatcharoenwitthaya Wattana Sukeepaisarnjaroen Teerha Piratvisuth Satawat Thongsawat Theeranun Sanpajit Soonthorn Chonprasertsuk Woramon Jeamsripong Ekawee Sripariwuth Piyawat Komolmit Tanisa Patcharatrakul Rattana Boonsirichan Chalermrat Bunchorntavakul Supoj Tuntipanichteerakul Tawesak Tanwandee for the Thai Association for the Study of the Liver on Chronic Hepatitis B 《Journal of gastroenterology and hepatology》2016,31(11):1874-1881
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Sararak Choosakul Kamin Harinwan Sakkarin Chirapongsathorn Krit Opuchar Theeranun Sanpajit Wanich Piyanirun Chaipichit Puttapitakpong 《Pancreatology》2018,18(5):507-512
Background/Objectives
Aggressive fluid resuscitation is recommended for initial management of acute pancreatitis. However, there are few studies which focus on types of fluid therapy.Methods
We performed a randomized controlled trial in patients with acute pancreatitis. The patients were randomized into two groups. Each group received Normal Saline solution (NSS) or Lactated Ringer's solution (LRS) through a goal-directed fluid resuscitation protocol. Systemic inflammatory response syndrome (SIRS) at 24 and 48?h, mortality, presence of local complications and inflammatory markers were measured.Results
Forty-seven patients were included. Twenty-four patients (51%) received NSS and 23 patients received LRS. There was significant reduction in SIRS after 24?h among subjects who resuscitated with LRS compared with NSS (4.2% in NSS, 26.1% in LRS, P?=?0.02). However, SIRS reduction at 48?h was not different between groups (33.4% in NSS, 26.1% in LRS, P?=?0.88). Mortality was not different between NSS and LRS (4.2% in NSS, 0% in LRS, P?=?1.00). CRP, ESR and procalcitonin increased at 24?h and 48?h after admission with no difference between the two groups. Local complications were 29.2% in NSS and 21.7% in LRS (P?=?0.74). The median length of hospital stay was not significantly different in the two groups (5.5 days in NSS, 6 days in LRS, P?=?0.915).Conclusions
Lactated Ringer's solution was superior to NSS in SIRS reduction in acute pancreatitis only in the first 24?h. But SIRS at 48?h and mortality were not different between LRS and NSS. 相似文献3.
Praeploy Chomkhuntod Arreerat Jiamprasertboon Anurak Waehayee Teera Butburee Narong Chanlek Nararat Yong Theeranun Siritanon 《RSC advances》2019,9(33):19079
A facile molten salt technique is an interesting preparation method as it enables mass production of materials. With the use of CsNO3 salt, Cs-intercalated MnO2 hollow microflowers are obtained in this work. δ-MnO2 with a layered structure, instead of other allotropes with smaller structural cavities, is formed and stabilized by large Cs+ ions. Formation of the hollow microflowers is explained based on the Ostwald ripening process. The salt to starting agent ratio has little effect on the crystal structure and morphologies of the products but does influence the crystallinity, the interlayer distance, and the intercalating Cs+ content. The capacity of Cs+ in the structure and the interlayer distance are maximized when the weight ratio of CsNO3 : MnSO4 is 7 : 1. Cs–MnO2 obtained from this optimum ratio has most suitable crystallinity and interlayer distance, and consequently shows a highest specific capacitance of 155 F g−1 with excellent cycling performance. The obtained specific capacitance is comparable to that of other alkaline-intercalated MnO2, suggesting that Cs–MnO2 could be another interesting candidate for supercapacitor electrodes.Hollow microflowers of Cs intercalated MnO2 binessite are prepared by a facile molten salt method and tested for supercapacitor electrodes. 相似文献
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