全文获取类型
收费全文 | 82117篇 |
免费 | 41126篇 |
国内免费 | 32篇 |
专业分类
耳鼻咽喉 | 1556篇 |
儿科学 | 4305篇 |
妇产科学 | 700篇 |
基础医学 | 16121篇 |
口腔科学 | 5201篇 |
临床医学 | 12680篇 |
内科学 | 24229篇 |
皮肤病学 | 7569篇 |
神经病学 | 13688篇 |
特种医学 | 2357篇 |
外国民族医学 | 1篇 |
外科学 | 14523篇 |
综合类 | 64篇 |
一般理论 | 22篇 |
预防医学 | 4612篇 |
眼科学 | 1450篇 |
药学 | 5699篇 |
中国医学 | 1020篇 |
肿瘤学 | 7478篇 |
出版年
2023年 | 63篇 |
2022年 | 130篇 |
2021年 | 1427篇 |
2020年 | 5126篇 |
2019年 | 10920篇 |
2018年 | 10181篇 |
2017年 | 11516篇 |
2016年 | 12155篇 |
2015年 | 12043篇 |
2014年 | 11979篇 |
2013年 | 12460篇 |
2012年 | 4354篇 |
2011年 | 4287篇 |
2010年 | 9052篇 |
2009年 | 5370篇 |
2008年 | 2296篇 |
2007年 | 1163篇 |
2006年 | 1216篇 |
2005年 | 938篇 |
2004年 | 956篇 |
2003年 | 939篇 |
2002年 | 996篇 |
2001年 | 911篇 |
2000年 | 849篇 |
1999年 | 400篇 |
1998年 | 106篇 |
1997年 | 66篇 |
1996年 | 57篇 |
1995年 | 46篇 |
1994年 | 49篇 |
1993年 | 40篇 |
1992年 | 111篇 |
1991年 | 98篇 |
1990年 | 94篇 |
1989年 | 75篇 |
1988年 | 77篇 |
1987年 | 55篇 |
1986年 | 59篇 |
1985年 | 53篇 |
1984年 | 48篇 |
1983年 | 34篇 |
1982年 | 53篇 |
1981年 | 36篇 |
1979年 | 33篇 |
1978年 | 23篇 |
1977年 | 31篇 |
1974年 | 29篇 |
1973年 | 36篇 |
1972年 | 31篇 |
1969年 | 32篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Mette Nissen Tiina‐Mari Ikheimo Jukka Huttunen Ville Leinonen Henna‐Kaisa Jyrkknen Mikael von und zu Fraunberg 《Neuromodulation》2021,24(1):102-111
ObjectiveSpinal cord stimulation (SCS) is an effective treatment in failed back surgery syndrome (FBSS). We studied the effect of preimplantation opioid use on SCS outcome and the effect of SCS on opioid use during a two-year follow-up period.Materials and methodsThe study cohort included 211 consecutive FBSS patients who underwent an SCS trial from January 1997 to March 2014. Participants were divided into groups, which were as follows: 1) SCS trial only (n = 47), 2) successful SCS (implanted and in use throughout the two-year follow-up period, n = 131), and 3) unsuccessful SCS (implanted but later explanted or revised due to inadequate pain relief, n = 29). Patients who underwent explantation for other reasons (n = 4) were excluded. Opioid purchase data from January 1995 to March 2016 were retrieved from national registries.ResultsHigher preimplantation opioid doses associated with unsuccessful SCS (ROC: AUC = 0.66, p = 0.009), with 35 morphine milligram equivalents (MME)/day as the optimal cutoff value. All opioids were discontinued in 23% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.004). Strong opioids were discontinued in 39% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.04). Mean opioid dose escalated from 18 ± 4 MME/day to 36 ± 6 MME/day with successful SCS and from 22 ± 8 MME/day to 82 ± 21 MME/day with unsuccessful SCS (p < 0.001).ConclusionsHigher preimplantation opioid doses were associated with SCS failure, suggesting the need for opioid tapering before implantation. With continuous SCS therapy and no explantation or revision due to inadequate pain relief, 39% of FBSS patients discontinued strong opioids, and 23% discontinued all opioids. This indicates that SCS should be considered before detrimental dose escalation. 相似文献
2.
3.
Deitelzweig Steve Luo Xuemei Nguyen Jennifer L. Malhotra Deepa Emir Birol Russ Cristina Li Xiaoyan Lee Theodore C. Ferri Mauricio Wiederkehr Danny Reimbaeva Maya Barnes Geoffrey D. Piazza Gregory 《Journal of thrombosis and thrombolysis》2022,54(4):696-696
Journal of Thrombosis and Thrombolysis - 相似文献
4.
5.
6.
7.
Hyun Jong Choi Jong Ho Moon Yun Nah Lee Hyun Su Kim Ji Su Ha Tae Hoon Lee Sang‐Woo Cha Young Deok Cho Sang‐Heum Park 《Digestive endoscopy》2015,27(7):772-775
Direct peroral cholangioscopy (POC) using an ultra‐slim upper endoscope is one modality of POC for intraductal endoscopic evaluation and treatment of the bile duct. Choledochoduodenostomy (CDS) is one modality of biliary bypass surgery that provides a new route to the bile duct. We carried out direct POC using an ultra‐slim upper endoscope without the use of accessories in 10 patients (four sump syndromes, three bile duct strictures and three intrahepatic duct stones) previously undergoing surgical CDS. Direct POC was successful in all patients. The use of an intraductal balloon catheter was required in one patient for advancement of the endoscope into the bile duct. Distal bile ducts with sump syndromes were cleared using baskets and water irrigation under direct POC. Cholangiocarcinoma was diagnosed in one patient with hilar bile duct stricture after cholangioscopic evaluation and a targeting forceps biopsy under direct POC. Intrahepatic duct stones were successfully extracted after intraductal fragmentation under direct POC. Oozing bleeding occurred during intraductal lithotripsy but stopped spontaneously. Direct POC using an ultra‐slim upper endoscope without the assistance of accessories can easily be carried out in patients undergoing CDS. 相似文献
8.
9.
Well‐being,health and fitness of children who use wheelchairs: Feasibility study protocol to develop child‐centred ‘keep‐fit’ exercise interventions 下载免费PDF全文
10.
Interprofessional collaboration and communication in nursing homes: a qualitative exploration of problems in medical care for nursing home residents – study protocol 下载免费PDF全文