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排序方式: 共有98条查询结果,搜索用时 8 毫秒
1.
Implementing Accreditation Systems (23 May 1994, Treviso, Italy) 总被引:1,自引:0,他引:1
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CLAIRE KERR BRONA C MCDOWELL JACKIE PARKES MIKE STEVENSON AIDAN P COSGROVE 《Developmental medicine and child neurology》2011,53(1):61-67
Aim The aim of this study was to use a prospective longitudinal study to describe age‐related trends in energy efficiency during gait, activity, and participation in ambulatory children with cerebral palsy (CP). Method Gross Motor Function Measure (GMFM), Paediatric Evaluation of Disability Inventory (PEDI), and Lifestyle Assessment Questionnaire‐Cerebral Palsy (LAQ‐CP) scores, and energy efficiency (oxygen cost) during gait were assessed in representative sample of 184 children (112 male; 72 female; mean age 10y 9mo; range 4–16y) with CP. Ninety‐four children had unilateral spastic CP, 84 bilateral spastic CP, and six had other forms of CP. Fifty‐seven were classified as Gross Motor Function Classification System (GMFCS) level I, 91 as level II, 22 as level III, and 14 as level IV). Assessments were carried out on two occasions (visit 1 and visit 2) separated by an interval of 2 years and 7 months. A total of 157 participants returned for reassessment. Results Significant improvements in mean raw scores for GMFM, PEDI, and LAQ‐CP were recorded; however, mean raw oxygen cost deteriorated over time. Age‐related trends revealed gait to be most inefficient at the age of 12 years, but GMFM scores continued to improve until the age of 13 years, and two PEDI subscales to age 14 years, before deteriorating (p<0.05). Baseline score was consistently the single greatest predictor of visit 2 score. Substantial agreement in GMFCS ratings over time was achieved (κlw=0.74–0.76). Interpretation These findings have implications in terms of optimal provision and delivery of services for young people with CP to maximize physical capabilities and maintain functional skills into adulthood. 相似文献
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AZZA TAGELSIR RITA CAUWELS SARA Van AKEN JACKIE VANOBBERGEN LUC C. MARTENS 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2011,21(1):13-22
International Journal of Paediatric Dentistry 2011; 21: 13–22 Introduction. The aim of the study was to investigate caries experience and dental care index in diabetic children and to determine if correlation exists between caries experience and metabolic control, insulin treatment, and the duration of diabetes. Materials and methods. The study group consisted of 52 children and adolescents, 3–16 years of age with type 1 diabetes attending the outpatient diabetic clinic at Ghent University Hospital, Belgium. Fifty healthy subjects recruited from the paediatric dental clinic served as the control group. Caries lesions were assessed using DMF‐index both at cavity and non‐cavity levels. Participants and/or their guardians provided information about oral hygiene habits and dietary habits. Diabetes‐related data (type, duration, insulin regimen) were collected from medical records and completed with the lab data on HbAlc. Conclusion. It became clear that, although children with type 1 diabetes mellitus could be expected to run a potential high caries risk taking into account the diabetes‐associated biological and behavioural alterations, no significant differences were observed regarding caries experience and dental care between diabetic children and healthy controls. The level of untreated dental decay among the diabetic children is, however, considerably high, which was reflected by a significant lower dental attendance. 相似文献
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RAJIV SANKARANARAYANAN M.B.B.S M.R.C.P. MICHAEL A. JAMES M.D. F.R.C.P. BOGDAN NUTA M.R.C.P. MANDIE TOWNSEND M.B.B.Ch. M.R.C.P. SUJATA KESAVAN M.B.B.S. M.R.C.P. STEPHANIE BURTCHAELL B.Sc. R.N. RUSSELL HOLLOWAY 《Pacing and clinical electrophysiology : PACE》2008,31(12):1612-1619
Background: Atrial fibrillation (AF) is associated with increased mortality and a higher complication rate postmyocardial infarction (MI), but the exact mechanisms are unknown. We investigated whether AF predisposes to ventricular arrhythmia in postmyocardial infarct patients, thereby accounting for increased mortality. Methods: Five hundred consecutive patients admitted to our coronary care unit with acute MI were monitored for in‐hospital arrhythmias. Detailed information was also compiled on past history, co‐morbidities, electrolyte disturbances, drug therapies, and ejection fraction. Mortality data were collected for an average of 5.5 years. Results: The results have shown that the incidence of ventricular fibrillation (VF) is much greater in patients presenting with AF (P = 0.03) and multivariate analysis has shown that AF is independently associated with the development of VF. This association occurs principally in patients who are admitted with AF (P = 0.01) rather than those who develop it during their admission, although these patients are also at mildly increased risk. The increased incidence of VF does account for increased mortality in the AF patients but does not explain all of their excess risk. There was no association between AF and ventricular tachycardia (VT); P = 0.50. Conclusions: In conclusion, AF on admission to the hospital with acute MI is associated with an increased risk of VF and subsequent mortality. 相似文献
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We have determined the chromosomal location of the human cardiac/slow skeleletal muscle troponin C gene (TNNC1) to the short arm of chromosome 3 using somatic cell hybrids. PCR-based analysis of a 'monochromosomal' hybrid panel identified the presence of the TNNC1 gene on human chromosome 3 and subsequent analysis of the Genebridge4 radiation hybrid panel located the gene between D3S3118 (7·3cR) and GCT4B10 (4·2cR) with a lod score of >3·0. 相似文献
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The prevalence of taurodontism in Down's syndrome 总被引:1,自引:0,他引:1
J. BELL C. R. CIVIL G. C. TOWNSEND R. H. BROWN 《Journal of intellectual disability research : JIDR》1989,33(6):467-476
ABSTRACT. Taurodontism, a condition in which the pulp chambers of teeth are elongated, was observed in extracted lower molars of 12 out of 33 (36.4%) individuals with Down's syndrome (DS). It is suggested that this high prevalence is associated with a delayed ingrowth and fusion of the epithelial flaps of the developing root sheath and that taurodontism represents one of several characteristic morphological dental features in DS that result from decreased mitotic activity of cells in developing tooth germs. 相似文献
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