排序方式: 共有19条查询结果,搜索用时 15 毫秒
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Schistosoma mansoni and HIV acquisition in fishing communities of Lake Victoria,Uganda: a nested case–control study 下载免费PDF全文
Ali Ssetaala Jessica Nakiyingi‐Miiro Gershim Asiki Nassim Kyakuwa Juliet Mpendo Govert J. Van Dam Paul L. Corstjens Pietro Pala Leslie Nielsen Jan De Bont Giuseppe Pantaleo Noah Kiwanuka Pontiano Kaleebu Anatoli Kamali Alison M. Elliott 《Tropical medicine & international health : TM & IH》2015,20(9):1190-1195
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Pilot study of antibodies against varicella zoster virus and human immunodeficiency virus in relation to the risk of developing stroke,nested within a rural cohort in Uganda 下载免费PDF全文
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Shukri F. Mohamed Tilahun Nigatu Haregu Olalekan A. Uthman Christopher Khayeka-Wandabwa Stella Kagwiria Muthuri Gershim Asiki Catherine Kyobutungi Paramjit Gill 《Global Heart》2021,16(1)
Background:In the era of double burden of infectious and non-communicable diseases in sub-Saharan Africa, the burden of multimorbidity is likely to be common. However, there is limited evidence on the burden and its associated factors in the sub-Saharan African context.Objective:The aim of this study was to determine the levels and identify determinants of multimorbidity from chronic conditions in two urban slums in Nairobi.Methods:Data collected from 2003 study participants aged 40–60 years in two urban slums of the Nairobi Urban Health and Demographic Surveillance System in 2015 were used. Using self-report, anthropometry and key biomarkers, data on 16 conditions including chronic diseases, behavioral disorders and metabolic abnormalities were gathered. Lifetime multimorbidity defined by the occurrence of at least two chronic conditions in an individual at any time during their life course was computed. Factors associated with lifetime multimorbidity were identified using multiple logistic regression.Findings:A total of 2,081 chronic conditions were identified among 1,302 individuals. While 701 (35.0%) had no chronic condition, single morbidity was reported in 726 (36.2%) of the study population. The overall prevalence of lifetime multimorbidity was 28.7%. The prevalence of dyads and triads of simultaneous occurrences of conditions (episodic multimorbidity) was 20.8% and 6.1%, respectively. Single morbidity was positively associated with gender and alcohol consumption; and negatively associated with employment. Women, older people, the unemployed, current smokers and current alcohol consumers had higher levels of lifetime multimorbidity in the study population.Interpretation:The findings of this study indicate that a considerable proportion of adults living in urban slums experience multimorbidity from chronic conditions. Further studies with a better rigor to establish temporal associations between socio-demographic factors and the occurrence of chronic conditions are needed to explore the impacts and implications on health status and health system. 相似文献
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Sylvia Kusemererwa Andrew Abaasa Martin Onyango Annalene M. Nel Michelle Isaacs Gershim Asiki 《AIDS and behavior》2018,22(1):131-138
Contraceptive preferences of women at risk for HIV acquisition are not well documented. We report on contraceptive choices among women residing in small townships in southwestern Uganda. This was part of preparatory efforts for recruitment into the Ring Study, a phase 3 microbicide trial, between July 2013 and October 2014. Clinicians provided contraceptives per a woman’s choice. HIV testing and screening for other sexually transmitted infections were done at first contact and at screening for the trial. Contraceptive choice was summarized by demographics and regression analysis to show factors associated with use of the injectable method. Of 6725 women contacted, 489 were prescreened. Of these 489 women, most (306, 63%) were already using contraception. Injectables were most preferred (58.7%), followed by implants (23.9%). Women living with a regular sexual partner preferred the injectable method (61.0%, P?=?0.06), compared with other methods. Women at risk for HIV infection are willing to initiate use of modern contraceptives, which may reduce study dropout during intervention trials due to unintended pregnancy. Registration no: NCT01539226. 相似文献
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Richard E. Sanya Erin Stewart Johnston Peter Kibe Mahmoud Werfalli Sloan Mahone Naomi S. Levitt Kerstin Klipstein-Grobusch Gershim Asiki 《Tropical medicine & international health : TM & IH》2023,28(2):80-89
Objective
There is insufficient evidence on the role of self-financing patient support groups in the control of blood pressure (BP) and/or diabetes in low- and middle-income countries (LMICs). We conducted a systematic review to investigate the effectiveness of these groups in BP and glycaemic control.Methods
We searched PubMed, Embase, SCOPUS, Web of Science, Global Health, African Journals Online, CINAHL and African Index Medicus for published peer-reviewed articles from inception up to November 2021. Grey literature was obtained from OpenGrey. Studies on patient support groups for hypertension and/or diabetes with a component of pooling financial resources, conducted in LMICs, were included. Narrative reviews, commentaries, editorials and articles published in languages other than English and French were excluded. Study quality and risk of bias were assessed using the National Institutes of Health Quality assessment tool and the revised Cochrane risk-of-bias tool. Results are reported according to PRISMA guidelines.Results
Of 724 records screened, three studies met the criteria: two trials conducted in Kenya and a retrospective cohort study conducted in Cambodia. All studies reported improvement in BP control after 12 months follow-up with reductions in systolic BP of 23, 14.8, and 16.9 mmHg, respectively. Two studies reported diabetes parameters. The first reported improvement in HbA1c (reduction from baseline 10.8%, to 10.6% at 6 months) and random blood sugar (baseline 8.9 mmol/L, to 8.5 mmol/L at 6 months) but these changes did not achieve statistical significance. The second reported a reduction in fasting blood glucose (baseline—216 mg/dl, 12 months—159 mg/dl) in diabetic patients on medication.Conclusion
Self-financing patient support groups for diabetes and hypertension are potentially effective in the control of BP and diabetes in LMICs. More studies are needed to add to the scarce evidence base on the role of self-financing patient support groups. 相似文献10.
Pneumonic plague cluster, Uganda, 2004 总被引:1,自引:0,他引:1
Begier EM Asiki G Anywaine Z Yockey B Schriefer ME Aleti P Ogden-Odoi A Staples JE Sexton C Bearden SW Kool JL 《Emerging infectious diseases》2006,12(3):460-467
The public and clinicians have long-held beliefs that pneumonic plague is highly contagious; inappropriate alarm and panic have occurred during outbreaks. We investigated communicability in a naturally occurring pneumonic plague cluster. We defined a probable pneumonic plague case as an acute-onset respiratory illness with bloody sputum during December 2004 in Kango Subcounty, Uganda. A definite case was a probable case with laboratory evidence of Yersinia pestis infection. The cluster (1 definite and 3 probable cases) consisted of 2 concurrent index patient-caregiver pairs. Direct fluorescent antibody microscopy and polymerase chain reaction testing on the only surviving patient's sputum verified plague infection. Both index patients transmitted pneumonic plague to only 1 caregiver each, despite 23 additional untreated close contacts (attack rate 8%). Person-to-person transmission was compatible with transmission by respiratory droplets, rather than aerosols, and only a few close contacts, all within droplet range, became ill. 相似文献