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排序方式: 共有195条查询结果,搜索用时 15 毫秒
1.
S Kostianev K Terziyski B Marinov 《The European respiratory journal》2007,30(1):181-2; author reply 182-3
2.
Victor A. Sorokin Vladimir F. Fedorov Victor S. Leontiev Yuri P. Blagoi Vladimir L. Galkin 《Macromolecular chemistry and physics.》1987,188(10):2301-2309
The helix-coil transition in Phage T2 DNA in the presence of 6,4 · 10?3 mol/l Mn2+ is studied using light scattering and UV spectroscopy. The transition range is about 0,5°C. Near the temperature of the end of melting Tf the molecular weight Mw and the radius of gyration Rz of the complex are observed to decrease to about one half. At a temperature 0,1–0,25°C higher than Tf, Mw and Rz pass through a minimum, which implies that aggregation is preceded by unwinding of DNA strands. Thus, rise in temperature rather than Mn2+ -induced aggregation causes DNA + Mn2+ melting. 相似文献
3.
Long saphenous vein (LSV) is considered an optimal plastic material for arterial reconstructions in revascularization of the myocardium and in the femoral-popliteal segment. The authors analyze the results from the investigation of the operation material from 12 patients with obliterating atherosclerosis of the lower limbs in which reversed LSV has been previously used for arterial bypass grafts. Material is taken during the second operation performed between two days and 18 months after the first reconstruction. In the early period after LSV implantation into the arterial blood flow there is a prevalence of destructive alterations which are mainly manifested in the intima and internal layers of the media. In later periods a massive layer is formed growing into the venous vascular lumen designated as "néo-intima". Investigations of its structure and of mechanisms of its formation could enable the regulation of this process by clinicists. 相似文献
4.
The authors make a clinical and pharmacological overview of the possibilities of application in the obstetrician practice of part of the medicines of the company Pfiser. Some of these medicines have no analogue in Bulgaria--i.e. Prostin 15M. The authors outline the advantages of the Pfiser medicines in comparison with other medicines with similar action. 相似文献
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AbstractDespite the voluminous current literature the potential of nimodipine to modify the outcome in experimental cerebral ischaemia remains a controversial matter. The authors have evaluated in controlled double blind experiments the influence of a continuous i.v. infusion of the drug (1 ¼g kg-1 min-1) upon infarct size, histopathology and neurological outcome in rats with permanent middle cerebral artery (MCA) occlusion. The infusion was started 20 min before induction of ischaemia and continued 4 hours thereafter. The nimodipine treated animals were subdivided into hypotensive (MABP lower than 85 mmHg for more than 5 min after arterial occlusion) and normotensive groups. Infarction size, documented by TTC, H&E and Nissl staining was significantly smaller (p < 0.001) in nimodipine normotonic rats than the lesions in placebo and saline treated ratsas well compared with hypotonic nimodipine animals (largest infarction). These differences were found to be entirely at the expense of the cortical (frontoparietal) component of the lesion, suggesting ‘penumbra’ action of the drug. Moreover, nimodipine normotonic rats displayed lower cortical neuronal injury in the periinfarct zone. These findings were corroborated by corresponding better neurological scores. Our results indicate that nimodipine is effective in reducing focal cerebral ischaemia, provided the MABP is maintained higher than 85 mmHg. 相似文献
8.
SG Landt GK Marinov A Kundaje P Kheradpour F Pauli S Batzoglou BE Bernstein P Bickel JB Brown P Cayting Y Chen G Desalvo C Epstein KI Fisher-Aylor G Euskirchen M Gerstein J Gertz AJ Hartemink MM Hoffman VR Iyer YL Jung S Karmakar M Kellis PV Kharchenko Q Li T Liu XS Liu L Ma A Milosavljevic RM Myers PJ Park MJ Pazin MD Perry D Raha TE Reddy J Rozowsky N Shoresh A Sidow M Slattery JA Stamatoyannopoulos MY Tolstorukov KP White S Xi PJ Farnham JD Lieb BJ Wold M Snyder 《Genome research》2012,22(9):1813-1831
9.
Using the pectoralis major myocutaneous flap is a good opportunity for one-stage reconstruction of the removed hypopharynx after total laryngopharyngectomy. The authors share their experience with five patients who underwent this kind of operation for T4 cancer of the hypopharynx and discuss their results. 相似文献
10.
Ivanova R Veselinova T Marinov E Gorchev G Tsetkov Ch Lalov S 《Akusherstvo i ginekologii?a》1999,38(4):35-37
A retrospective morphological research is made on the material of 78 cases from vulva for a three years period of time. They are identified 35 cases with invasive carcinoma, 2 c. with noninvasive carcinoma, 19 c. with vulvar dystrophia and squamous intraepithelial neoplasia (VIN). The invasive carcinomas are divided: keratinizing squamous cell carcinoma--31 c.; nonkeratinizing squamous cell carcinoma--3 c; adenoid squamous cell carcinoma--1. In all operated patients are examined the changes in the tissues surrounding the tumor and in the underlying tissue. They are divided in: lichen sclerosus, squamous cell hyperplasia, mixed dystrophia and squamous intraepithelial neoplasia. The morphological variants of squamous carcinoma, the epithelial changes and the patient's age are paralleled. 相似文献