全文获取类型
收费全文 | 1050篇 |
免费 | 67篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 83篇 |
妇产科学 | 6篇 |
基础医学 | 133篇 |
口腔科学 | 35篇 |
临床医学 | 136篇 |
内科学 | 198篇 |
皮肤病学 | 13篇 |
神经病学 | 62篇 |
特种医学 | 120篇 |
外科学 | 86篇 |
综合类 | 20篇 |
一般理论 | 2篇 |
预防医学 | 95篇 |
眼科学 | 3篇 |
药学 | 90篇 |
中国医学 | 1篇 |
肿瘤学 | 32篇 |
出版年
2021年 | 9篇 |
2019年 | 9篇 |
2018年 | 12篇 |
2017年 | 7篇 |
2016年 | 9篇 |
2015年 | 15篇 |
2014年 | 24篇 |
2013年 | 35篇 |
2012年 | 39篇 |
2011年 | 43篇 |
2010年 | 46篇 |
2009年 | 31篇 |
2008年 | 35篇 |
2007年 | 54篇 |
2006年 | 31篇 |
2005年 | 24篇 |
2004年 | 12篇 |
2003年 | 21篇 |
2002年 | 23篇 |
2001年 | 24篇 |
2000年 | 13篇 |
1999年 | 25篇 |
1998年 | 48篇 |
1997年 | 52篇 |
1996年 | 43篇 |
1995年 | 20篇 |
1994年 | 31篇 |
1993年 | 22篇 |
1992年 | 31篇 |
1991年 | 22篇 |
1990年 | 19篇 |
1989年 | 25篇 |
1988年 | 41篇 |
1987年 | 21篇 |
1986年 | 23篇 |
1985年 | 14篇 |
1984年 | 19篇 |
1983年 | 15篇 |
1982年 | 17篇 |
1981年 | 17篇 |
1980年 | 9篇 |
1979年 | 8篇 |
1978年 | 12篇 |
1977年 | 7篇 |
1976年 | 11篇 |
1975年 | 7篇 |
1974年 | 9篇 |
1972年 | 4篇 |
1967年 | 7篇 |
1960年 | 3篇 |
排序方式: 共有1140条查询结果,搜索用时 15 毫秒
1.
S. Moss H. Prosser B. Ibbotson D. Goldberg 《Journal of intellectual disability research : JIDR》1996,40(5):457-465
This paper investigates differences in the nature and frequency of psychiatric symptoms reported by patients with learning disability and by key informants. The study involved psychiatric assessment of 100 patients with learning disabilities and key informants using the Psychiatric Assessment Schedule for Adults with a Developmental Disability (PAS-ADD), a semi-structured psychiatric interview developed specifically for people who have a learning disability. There was considerable disagreement between respondent and informant interviews; only 40.7% of cases were detected by both interviews. Respondents were more likely to report on autonomic symptoms and certain psychotic phenomena. Other anxiety and depression symptoms were more frequently reported by infcrnnants. The results indicate that it is crucial for sensitive case detection to complete both interviews where possible. If the respondent cannot be interviewed, panic disorder or phobias may be particularly difficult to detect. 相似文献
2.
3.
Rupture of the distal biceps tendon: evaluation with MR imaging 总被引:2,自引:0,他引:2
4.
Androgen receptor YAC transgenic mice carrying CAG 45 alleles show trinucleotide repeat instability 总被引:1,自引:15,他引:1
La Spada AR; Peterson KR; Meadows SA; McClain ME; Jeng G; Chmelar RS; Haugen HA; Chen K; Singer MJ; Moore D; Trask BJ; Fischbeck KH; Clegg CH; McKnight GS 《Human molecular genetics》1998,7(6):959-967
X-linked spinal and bulbar muscular atrophy (SBMA) is caused by a CAG
repeat expansion in the first exon of the androgen receptor (AR) gene.
Disease-associated alleles (37-66 CAGs) change in length when transmitted
from parents to offspring, with a significantly greater tendency to shift
size when inherited paternally. As transgenic mice carrying human AR cDNAs
with 45 and 66 CAG repeats do not display repeat instability, we attempted
to model trinucleotide repeat instability by generating transgenic mice
with yeast artificial chromosomes (YACs) carrying AR CAG repeat expansions
in their genomic context. Studies of independent lines of AR YAC transgenic
mice with CAG 45 alleles reveal intergenerational instability at an overall
rate of approximately 10%. We also find that the 45 CAG repeat tracts are
significantly more unstable with maternal transmission and as the
transmitting mother ages. Of all the CAG/CTG repeat transgenic mice
produced to date the AR YAC CAG 45 mice are unstable with the smallest
trinucleotide repeat mutations, suggesting that the length threshold for
repeat instability in the mouse may be lowered by including the appropriate
flanking human DNA sequences. By sequence-tagged site content analysis and
long range mapping we determined that one unstable transgenic line has
integrated an approximately 70 kb segment of the AR locus due to
fragmentation of the AR YAC. Identification of the cis - acting elements
that permit CAG tract instability and the trans -acting factors that
modulate repeat instability in the AR YAC CAG 45 mice may provide insights
into the molecular basis of trinucleotide repeat instability in humans.
相似文献
5.
6.
It is well recognized that the ability to cryopreserve unfertilizedhuman oocytes would make a significant contribution to infertilitytreatment. However, despite considerable interest, very fewsuccessful pregnancies have arisen from cryopreserved oocytesafter thawing, insemination and transfer of the subsequent embryo.The reasons for this lack of progress may well result from adearth of information on how the various biophysical changesduring a cryopreservation regimen affect human oocyte function.Recently, fundamental studies on the effects of cooling, membranepermeability, cryoprotectant addition and ice formation havebeen performed on human oocytes by a number of groups, and theseform the basis of the current review. It is likely that successfulhuman oocyte cryopreservation will only follow once these factorsare fully understood, but the existing base of knowledge shouldprovide a platform for further improvements in the techniquescurrently employed. 相似文献
7.
8.
Functions of neurons in enteric plexuses of cat intestine 总被引:4,自引:0,他引:4
9.
Electrical parameters of smooth muscle cells 总被引:5,自引:0,他引:5
10.
KM Kanal NJ Hangiandreou AM Sykes HE Eklund PA Araoz JA Leon BJ Erickson 《Journal of digital imaging》2002,14(1):30-37
The aims of this work were to measure the accuracy of one continuous speech recognition product and dependence on the speaker's
gender and status as a native or nonnative English speaker, and evaluate the product's potential for routine use in transcribing
radiology reports. IBM MedSpeak/Radiology software, version 1.1 was evaluated by 6 speakers. Two were nonnative English speakers,
and 3 were men. Each speaker dictated a set of 12 reports. The reports included neurologic and body imaging examinations performed
with 6 different modalities. The dictated and original report texts were compared, and error rates for overall, significant,
and subtle significant errors were computed. Error rate dependence on modality, native English speaker status, and gender
were evaluated by performing ttests. The overall error rate was 10.3 +/- 3.3%. No difference in accuracy between men and women
was found; however, significant differences were seen for overall and significant errors when comparing native and nonnative
English speakers (P = .009 and P = .008, respectively). The speech recognition software is approximately 90% accurate, and
while practical implementation issues (rather than accuracy) currently limit routine use of this product throughout a radiology
practice, application in niche areas such as the emergency room currently is being pursued. This methodology provides a convenient
way to compare the initial accuracy of different speech recognition products, and changes in accuracy over time, in a detailed
and sensitive manner. 相似文献